Results 11 to 20 of about 93,495 (232)

Transdermal Permeation of Drugs in Various Animal Species [PDF]

open access: yesPharmaceutics, 2017
Excised human skin is utilized for in vitro permeation experiments to evaluate the safety and effect of topically-applied drugs by measuring its skin permeation and concentration. However, ethical considerations are the major problem for using human skin to evaluate percutaneous absorption.
Hiroaki Todo
exaly   +7 more sources

Permeation-Enhancing Strategies for Transdermal Delivery of Cannabinoids

open access: yesCannabis & Cannabinoid Research, 2023
Introduction: This review aims to provide an overview of the advancements and status of clinical studies and potential permeation-enhancing strategies in the transdermal delivery of cannabinoids.
Skov, Anne Ladegaard   +2 more
core   +3 more sources

Fabrication, appraisal, and transdermal permeation of sildenafil citrate-loaded nanostructured lipid carriers versus solid lipid nanoparticles

open access: yesInternational Journal of Nanomedicine, 2011
Yosra SR Elnaggar1, Magda A El-Massik2, Ossama Y Abdallah11Department of Pharmaceutics, Faculty of Pharmacy, Alexandria University, 2Department of Pharmaceutics, Faculty of Pharmacy and Drug Manufacturing, Pharos University, Alexandria, EgyptAbstract ...
Elnaggar YS, El-Massik MA, Abdallah OY
doaj   +1 more source

Development of Novel Formulations to Enhance in Vivo Transdermal Permeation of Tocopherol

open access: yesActa Pharmaceutica, 2014
Tocopherol represents a big challenge for transdermal permeation owing to its extreme hydrophobicity and large molecular mass. The aim of the present study was to develop alpha-tocopherol (T) topical formulations and evaluate their ex vivo and in vivo ...
Nada Aly H.   +3 more
doaj   +3 more sources

Mechanism of transdermal permeation promotion of lipophilic drugs by ethosomes

open access: yesInternational Journal of Nanomedicine, 2017
Li Yang,1,* Lifang Wu,1,* Dongze Wu,2 Deshun Shi,3 Tai Wang,4 Xiaoliang Zhu4 1Department of Dermatology, Nanfang Hospital, Southern Medical University, Guangzhou, 2Department of Medicine and Therapeutics, The Prince of Wales Hospital, The Chinese ...
Wu L, Yang L, Wang T, Shi D, Zhu X, Wu D
core   +6 more sources

Mechanism investigation of ethosomes transdermal permeation. [PDF]

open access: yesInt J Pharm X, 2019
Ethosomes are widely used to promote transdermal permeation of both lipophilic and hydrophilic drugs, but the mechanism of interaction between the ethosomes and the skin remains unclear. In this work, it was exploded with several technologies and facilities.
Niu XQ   +10 more
europepmc   +4 more sources

Enhancement of transdermal permeation of cannabinoids and their pharmacodynamic evaluation in rats. [PDF]

open access: yesInt J Pharm, 2022
The objective of the present study was to enhance the transdermal permeation of cannabinoids: cannabidiol (CBD), cannabigerol (CBG) and tetrahydrocannabivarin (THCV) using chemical permeation enhancer approach and evaluate them for their anti-inflammatory effect in vivo in a paw edema model in rats.
Salau O, Bagde A, Kalvala A, Singh M.
europepmc   +3 more sources

Development of an optimised application protocol for sonophoretic transdermal delivery of a model hydrophilic drug [PDF]

open access: yes, 2011
It has now been known for over a decade that low frequency ultrasound can be used to effectively enhance transdermal drug penetration - an approach termed sonophoresis.
Abdul, Rasool   +2 more
core   +4 more sources

Jojoba oil-based microemulsion for transdermal drug delivery

open access: yesResearch in Pharmaceutical Sciences, 2021
Background and purpose: Microemulsions are gaining an increased interest in transdermal drug delivery. Microemulsions are stable, easy to prepare, and provide high solubilizing capacity for various drugs.
Shereen Mashhour Assaf   +4 more
doaj   +1 more source

A comprehensive review on invasomal carriers incorporating natural terpenes for augmented transdermal delivery

open access: yesFuture Journal of Pharmaceutical Sciences, 2022
Background Transdermal drug delivery is one of the most widely used drug administration routes, which offer several advantages over other routes of drug delivery.
Bhumika Kumar   +3 more
doaj   +1 more source

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