Results 11 to 20 of about 7,154 (195)

Mechanism of transdermal permeation promotion of lipophilic drugs by ethosomes. [PDF]

open access: yesInt J Nanomedicine, 2017
Ethosomes can promote the penetration of lipophilic drugs into the skin, but the underlying mechanism is still unknown. The purpose of this study was to investigate the mechanism of transdermal permeation promotion of lipophilic drugs by ethosomes. The formulation of ethosomes was optimized using the Box-Behnken experimental design, in which Rhodamine ...
Yang L   +5 more
europepmc   +6 more sources

EFFECT OF ESSENTIAL OILS ON TRANSDERMAL PERMEATION OF METOPROLOL SUCCINATE [PDF]

open access: yesBulletin of Pharmaceutical Sciences. Assiut University, 2021
The objective of the present study was to prepare a matrix-type transdermal drug delivery system containing metoprolol succinate and to evaluate the effect of essential oils on transdermal permeation of drug.
B. N. Suhagia   +5 more
doaj   +1 more source

The enantioselective enhancing effect and mechanistic insights of chiral enhancers in transdermal drug delivery

open access: yesAsian Journal of Pharmaceutical Sciences, 2023
Overlook of chiral consideration in transdermal drug delivery increases administrated dose and risk of side effects, decreasing therapeutical effects. To improve the transdermal delivery efficiency of eutomer, this work focused on investigating the law ...
Yang Zhang   +9 more
doaj   +1 more source

Enhanced Transdermal Delivery of Bisoprolol Hemifumarate via Combined Effect of Iontophoresis and Chemical Enhancers: Ex Vivo Permeation/In Vivo Pharmacokinetic Studies

open access: yesPharmaceutics, 2021
Bisoprolol hemifumarate (BH) is an antihypertensive drug that is used as first-line treatment for chronic hypertension and angina pectoris. Our study was performed to enhance the transdermal delivery of BH, a hydrophilic drug active with high molecular ...
Mahmoud H. Teaima   +5 more
doaj   +1 more source

Jojoba oil-based microemulsion for transdermal drug delivery

open access: yesResearch in Pharmaceutical Sciences, 2021
Background and purpose: Microemulsions are gaining an increased interest in transdermal drug delivery. Microemulsions are stable, easy to prepare, and provide high solubilizing capacity for various drugs.
Shereen Mashhour Assaf   +4 more
doaj   +1 more source

Study of the permeation-promoting effect and mechanism of solid microneedles on different properties of drugs

open access: yesDrug Delivery, 2023
In transdermal drug delivery systems, the physicochemical properties of the drug affect its percutaneous permeability. However, whether the physicochemical properties of drugs change their transdermal permeability in the presence of pores in the presence
Huahua Li   +10 more
doaj   +1 more source

A comprehensive review on invasomal carriers incorporating natural terpenes for augmented transdermal delivery

open access: yesFuture Journal of Pharmaceutical Sciences, 2022
Background Transdermal drug delivery is one of the most widely used drug administration routes, which offer several advantages over other routes of drug delivery.
Bhumika Kumar   +3 more
doaj   +1 more source

Temperature influencing permeation pattern of alfuzosin: An investigation using DoE

open access: yesMedicina, 2015
Background and objective: There has been relatively little investigation of the effect of temperature on skin permeation compared to other methods of penetration enhancement.
Satyanarayan Pattnaik   +4 more
doaj   +1 more source

Effect of microneedles on transdermal permeation enhancement of amlodipine [PDF]

open access: yesDrug Delivery and Translational Research, 2017
The present study aimed to investigate the effect of microneedle (MN) geometry parameters like length, density, shape and type on transdermal permeation enhancement of amlodipine (AMLO). Two types of MN devices viz. AdminPatch® arrays (ADM) (0.6, 1.2 and 1.5 mm lengths) and laboratory-fabricated polymeric MNs (PM) of 0.6 mm length were employed. In the
Buchi N, Nalluri   +6 more
openaire   +2 more sources

Transdermal Drug Delivery of Tazarotene: Determining Tazarotene’s Potential in Local Transdermal Therapy

open access: yesPharmaceutics, 2023
Retinoid-based drugs, while effective, are associated with systemic toxicity. Topical alternatives offer a safer option, and tazarotene, a third-generation synthetic retinoid, holds promise.
Helena Hamzehpour   +5 more
doaj   +1 more source

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