Results 41 to 50 of about 88,006 (229)
Modelling the effect of mixture components on permeation through skin [PDF]
, 2010 A vehicle influences the concentration of penetrant within the membrane, affecting its diffusivity in the skin and rate of transport. Despite the huge amount of effort made for the understanding and modelling of the skin absorption of chemicals, a ...
E.G. Samaras +11 more
core +1 more source
Pharmaceutics, 2021 The exponentially mounting cases of herpes simplex virus infection or cold sores have become a serious global concern. Acyclovir (ACV) and garlic oil (GO)-loaded lipid nanocarrier could be a promising therapeutic approach in alleviating cold sores, as ...
Alshaimaa M. Almehmady, Sarah A. Ali
doaj +1 more source
Optimization and Characterization of Chitosan Films for Transdermal Delivery of Ondansetron
Molecules, 2013 The aim of this study was to develop novel transdermal films of ondansetron HCl with high molecular weight chitosan as matrix polymer and 2-(2-ethoxy-ethoxy) ethanol (Transcutol®) as plasticizer. In this context, firstly the physicochemical properties of
Yıldız Özsoy +3 more
doaj +1 more source
The Relationship between Solubility and Transdermal Absorption of Tadalafil [PDF]
Advanced Pharmaceutical Bulletin, 2015 Purpose: The aim of this study was to find a relationship between drug solubility and its transdermal permeation and find the best vehicle composition to improve transdermal permeation of Tadalafil.
Hamed Hamishehkar +3 more
doaj +1 more source
NATURAL PERMEATION ENHANCER FOR TRANSDERMAL DRUG DELIVERY SYSTEM AND PERMEATION EVALUATION: A REVIEW [PDF]
, 2017 The transdermal drug delivery route is evolving as a potential route due to its advantages of bypassing the hepatic first pass metabolism, decreased side effects and gastrointestinal effects, improve patience compliance as it is a pain-free self ...
Asha Das, Abdul Baquee Ahmed
core +3 more sources
International Brazilian Journal of Urology, 2009 Purpose: The main objective of the investigation was to develop a transdermal therapeutic system for alfuzosin hydrochloride and to study the effects of polymeric system and loading dose on the in vitro skin permeation pattern.
Satyanarayan Pattnaik +4 more
doaj +1 more source
The Needle-Free Frontier: Redefining the Limits of Transdermal Insulin Delivery. [PDF]
Exploration (Beijing)Wei and colleagues reported a pH‐responsive, charge‐switchable polyzwitterionic polymer carrier that achieves non‐invasive transdermal insulin delivery without external energy input. The approach leverages adaptive compatibility with the cutaneous microenvironment to shuttle functional macromolecules across intact skin and achieve definitive systemic ...
Chen J +4 more
europepmc +2 more sources
Permeation enhancer strategies in transdermal drug delivery
Drug Delivery, 2014 Today, ∼74% of drugs are taken orally and are not found to be as effective as desired. To improve such characteristics, transdermal drug delivery was brought to existence. This delivery system is capable of transporting the drug or macromolecules painlessly through skin into the blood circulation at fixed rate.
Harneet, Marwah +3 more
openaire +2 more sources
Iraqi Journal of Pharmaceutical Sciences, 2020 This study designed to prepare ultrafine apixaban (APX) o/w nanoemulsion (NE) based gel with droplet size below 50 nm as a good method for transdermal APX delivery without using permeation enhancer, alternatively, the formulation components itself act as
Mustafa R. Abdulbaqi, Nawal A.Rajab
doaj +1 more source
In vitro evaluation of transdermal nicotine delivery systems commercially available in Brazil
Brazilian Journal of Pharmaceutical Sciences, 2013 The aim of this study was to develop and validate a method for evaluating the release and skin permeation from transdermal nicotine patches using the vertical diffusion cell (VDC).
André Luís Morais Ruela +5 more
doaj +1 more source