Results 51 to 60 of about 7,154 (195)
Ionic liquid-iontophoresis mediates transdermal delivery of sparingly soluble drugs
Drug DeliveryLow solubility restricted transdermal penetration of drugs. We aimed to develop a novel ionic liquid-iontophoresis (IL-IS) technology and assess their efficacy and primary factors in facilitating transdermal drug delivery.
Wenyan Gao +5 more
doaj +1 more source
Pharmaceutics, 2021 The study aimed to develop elastic-liposome-based transdermal delivery of desmopressin acetate for enhanced permeation to control enuresis, central diabetes insipidus, and traumatic injury. Elastic liposomes (ELs)-loaded desmopressin acetate was prepared,
Mohammad A. Altamimi +3 more
doaj +1 more source
Drug‐coated balloons: From conventional designs to next‐generation innovations in vascular therapy
BMEMat, EarlyView.This review traces the evolution of drug‐coated balloons (DCBs) from conventional designs to next‐generation platforms. We highlight innovations in balloon engineering, coating technologies, and therapeutic agents that enhance localized drug delivery while addressing challenges in efficiency, safety, and biocompatibility for vascular and emerging non ...
Lu Zhang +5 more
wiley +1 more source
Development of Novel Formulations to Enhance in Vivo Transdermal Permeation of Tocopherol
Acta Pharmaceutica, 2014 Tocopherol represents a big challenge for transdermal permeation owing to its extreme hydrophobicity and large molecular mass. The aim of the present study was to develop alpha-tocopherol (T) topical formulations and evaluate their ex vivo and in vivo ...
Nada Aly H. +3 more
doaj +1 more source
Effect of Ultrasound on Transdermal Permeation of Diclofenac
European Journal of Inflammation, 2006 During the last two decades the effects of ultrasound on the transdermal permeability to a wide variety of drugs have been extensively investigated. There is still some uncertainty regarding the mechanisms involved in ultrasonic permeation enhancement, thus we investigated the effect of ultrasonic treatment on the transdermal permeation of the NSAID ...
Van der Bijl P +3 more
openaire +2 more sources
BMEMat, EarlyView.TCPL, a transfersome with Tween 80 and PEI, enables efficient transdermal siNF‐κB delivery, resolving PEI's toxicity issue. It promotes lysosomal escape and effective transfection, silences NF‐κB, modulates immunity, and inhibits angiogenesis, alleviating psoriasis. With good biocompatibility, TCPL holds strong clinical translation potential. Schematic
Hui Xing +6 more
wiley +1 more source
International Journal of Nanomedicine, 2011 Yosra SR Elnaggar1, Magda A El-Massik2, Ossama Y Abdallah11Department of Pharmaceutics, Faculty of Pharmacy, Alexandria University, 2Department of Pharmaceutics, Faculty of Pharmacy and Drug Manufacturing, Pharos University, Alexandria, EgyptAbstract ...
Elnaggar YS, El-Massik MA, Abdallah OY
doaj
Microemulsion as a vehicle for transdermal permeation of nimesulide
Indian Journal of Pharmaceutical Sciences, 2006 Topical microemulsions of nimesulide, a poorly water-soluble nonsteroidal antiinflammatory drug, using olive oil as oil phase and Tween 80/iso-octanol as surfactant/co-surfactant were designed. Various concentrations of surfactant: co-surfactant (2:1, 3:1, 4:1) were used in constructing a pseudoternary phase diagram.
DV Derle, BSH Sagar, Sagar Pimpale
openaire +1 more source
Fish Scales: A Multifunctional Biomaterial from Nature
ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.Fish scales demonstrate nature's solution to impact protection through overlapping multilayered architecture. This biological design combines mineralized surfaces with collagen networks to achieve both flexibility and fracture resistance. The structural principles inspire advanced protective materials and biomedical implants, where damage tolerance ...
Liyao Dong, Xiaojie Sun, Xiguang Chen
wiley +1 more source
Scientia PharmaceuticaThis study aimed to evaluate Zn/Ag-electrode-printed patches for the transdermal delivery of small molecules through iontophoresis. The Zn/Ag-electrode-printed patches interact with biological liquid electrolytes and generate suitable microcurrents for ...
Cheng-Liang Peng +3 more
doaj +1 more source