Results 51 to 60 of about 7,205 (188)
Autonomous AI‐Driven Design for Skin Product Formulations
Advanced Intelligent Discovery, EarlyView.This review presents a comprehensive closed‐loop framework for autonomous skin product formulation design. By integrating artificial intelligence‐driven experiment selection with automated multi‐tiered assays, the approach shifts development from trial‐and‐error to intelligent optimisation.
Yu Zhang +5 more
wiley +1 more source
Transdermal Delivery of Nicardipine: An Approach to In Vitro Permeation Enhancement [PDF]
Drug Delivery, 2002 Nicardipine hydrochloride (NC-HCl), a calcium channel blocker for the treatment of chronic stable angina and hypertension, seems to be a potential therapeutic transdermal system candidate, mainly due to its low dose, short half-life, and high first-pass metabolism.
Reza, Aboofazeli +2 more
openaire +2 more sources
Advanced NanoBiomed Research, EarlyView.Beyond the green solvent paradigm, this review redefines Deep Eutectic Systems (DES) as programmable supramolecular nanoassemblies. We survey their biomedical convergence: stabilizing thermolabile mRNA to enable cold chain‐free logistics, reshaping transdermal microneedle delivery, enabling long‐term wearables via eutectogels, and utilizing Generative ...
Jeesu Moon, Min Seo Kim, Jae‐Seung Lee
wiley +1 more source
International Journal of Nanomedicine, 2011 Yosra SR Elnaggar1, Magda A El-Massik2, Ossama Y Abdallah11Department of Pharmaceutics, Faculty of Pharmacy, Alexandria University, 2Department of Pharmaceutics, Faculty of Pharmacy and Drug Manufacturing, Pharos University, Alexandria, EgyptAbstract ...
Elnaggar YS, El-Massik MA, Abdallah OY
doaj
Development of Novel Formulations to Enhance in Vivo Transdermal Permeation of Tocopherol
Acta Pharmaceutica, 2014 Tocopherol represents a big challenge for transdermal permeation owing to its extreme hydrophobicity and large molecular mass. The aim of the present study was to develop alpha-tocopherol (T) topical formulations and evaluate their ex vivo and in vivo ...
Nada Aly H. +3 more
doaj +1 more source
Effect of Ultrasound on Transdermal Permeation of Diclofenac
European Journal of Inflammation, 2006 During the last two decades the effects of ultrasound on the transdermal permeability to a wide variety of drugs have been extensively investigated. There is still some uncertainty regarding the mechanisms involved in ultrasonic permeation enhancement, thus we investigated the effect of ultrasonic treatment on the transdermal permeation of the NSAID ...
Van der Bijl P +3 more
openaire +2 more sources
Design Considerations for Polymer–Deep Eutectic Solvent Hybrid Systems for Transdermal Drug Delivery
Journal of Applied Polymer Science, EarlyView.Deep eutectic solvents (DESs) act as tunable, green excipients that modulate polymer structure–property relationships to enhance drug solubility, skin permeation, stability, and controlled release. Through hydrogen‐bond interactions, DES–polymer hybrid systems enable improved transdermal performance, offering a rational, design‐driven platform for ...
Madhavi Kailas Kapale +3 more
wiley +1 more source
Microemulsion as a vehicle for transdermal permeation of nimesulide
Indian Journal of Pharmaceutical Sciences, 2006 Topical microemulsions of nimesulide, a poorly water-soluble nonsteroidal antiinflammatory drug, using olive oil as oil phase and Tween 80/iso-octanol as surfactant/co-surfactant were designed. Various concentrations of surfactant: co-surfactant (2:1, 3:1, 4:1) were used in constructing a pseudoternary phase diagram.
DV Derle, BSH Sagar, Sagar Pimpale
openaire +1 more source
Bulletin of the Korean Chemical Society, EarlyView.PLGA‐based sustained‐release microneedles were developed for the delivery of desogestrel and ethinyl estradiol. The system enabled coordinated release of both drugs, suggesting its potential to improve dosing convenience as a long‐acting contraceptive platform.
Young‐Jin Kim +5 more
wiley +1 more source
Scientia PharmaceuticaThis study aimed to evaluate Zn/Ag-electrode-printed patches for the transdermal delivery of small molecules through iontophoresis. The Zn/Ag-electrode-printed patches interact with biological liquid electrolytes and generate suitable microcurrents for ...
Cheng-Liang Peng +3 more
doaj +1 more source