Results 71 to 80 of about 88,006 (229)
Alternatives to Biological Skin in Permeation Studies: Current Trends and Possibilities
Pharmaceutics, 2020 The transdermal route of drugs has received increased attention in recent years due to numerous advantages over the oral and injectable routes, such as avoidance of the hepatic metabolism, protection of drugs from the gastrointestinal tract, sustained ...
Rabin Neupane +4 more
doaj +1 more source
Advanced Science, EarlyView.This work develops a soft hybrid electronic system with printed thermoresponsive hydrogel electrodes, which enables high‐fidelity neural signal acquisition and stimulation. The system precisely assesses median and ulnar nerve injuries in clinical cases, realizing accurate diagnosis of neural impairment while ensuring customized adhesion regulation ...
Bo Pang +13 more
wiley +1 more source
Advanced Science, EarlyView.Sustained delivery of a shingles subunit vaccine from an injectable polymer–nanoparticle hydrogel enhanced the potency, durability, and breadth of immune responses in aged mice while minimizing inflammatory cytokine production and reactogenicity. This strategy decouples immunogenicity from reactogenicity and offers a promising approach to improve ...
Ye Eun Song +5 more
wiley +1 more source
Development of Novel Formulations to Enhance in Vivo Transdermal Permeation of Tocopherol
Acta Pharmaceutica, 2014 Tocopherol represents a big challenge for transdermal permeation owing to its extreme hydrophobicity and large molecular mass. The aim of the present study was to develop alpha-tocopherol (T) topical formulations and evaluate their ex vivo and in vivo ...
Nada Aly H. +3 more
doaj +1 more source
In vitro transdermal permeation of fenoterol hydrobromide
Journal of Advanced Research, 2012 AbstractThe aim of this study was to determine if transdermal penetration of fenoterol, a β-agonist drug, could be enhanced and controlled by formulation modification and formulation of transdermal patches. Pre-formulation studies were performed to determine the feasibility of a transdermal dosage form of fenoterol.
Elshafeey, Ahmed H. +3 more
openaire +3 more sources
Transkarbam 12 and caffeine transdermal permeation from oleocreams. 1. [PDF]
, 2009 The transdermal application of active substances and the related topic - skin barrier permeability were reviewed in theoretical part of this work.
Štiková, Jana
core +1 more source
Advanced Science, EarlyView.A disulfide‐sticker strategy, coupled with Ca2+ coordination, drives the hierarchical self‐assembly of a recombinant scallop adhesive protein into fishnet‐like nanostructures, affording a coating with versatile wet adhesion and intrinsic antioxidant activity. This biocompatible coating markedly promotes hair regeneration by activating follicular niches,
Lulu Wang +7 more
wiley +1 more source
Advanced Science, EarlyView.This work identified CPD3a as a potent, stable C‐nucleoside cordycepin derivative. When formulated into microneedle array for topical treatment, it ameliorated psoriasis by rebalancing immunity and enhancing antioxidant defenses. ABSTRACT Psoriasis is a chronic inflammatory disorder characterized by immune dysregulation and epidermal hyperplasia ...
Wenfang Pan +7 more
wiley +1 more source
Transdermal Delivery of Nicardipine: An Approach to In Vitro Permeation Enhancement [PDF]
Drug Delivery, 2002 Nicardipine hydrochloride (NC-HCl), a calcium channel blocker for the treatment of chronic stable angina and hypertension, seems to be a potential therapeutic transdermal system candidate, mainly due to its low dose, short half-life, and high first-pass metabolism.
Reza, Aboofazeli +2 more
openaire +2 more sources
Scientia PharmaceuticaThis study aimed to evaluate Zn/Ag-electrode-printed patches for the transdermal delivery of small molecules through iontophoresis. The Zn/Ag-electrode-printed patches interact with biological liquid electrolytes and generate suitable microcurrents for ...
Cheng-Liang Peng +3 more
doaj +1 more source