Results 71 to 80 of about 7,154 (195)

Enhanced delivery of hydrophilic peptides in vitro by transdermal microneedle pretreatment

open access: yesActa Pharmaceutica Sinica B, 2014
The aims of this study were to investigate the utility of solid microneedle arrays (150 µm in length) in enhancing transdermal delivery of peptides and to examine the relationship between peptide permeation rates and D2O flux.
Suohui Zhang, Yuqin Qiu, Yunhua Gao
doaj   +1 more source

The Association Between Stress‐Induced Hyperglycemia Ratio and Increased Urinary Albumin Excretion in Patients With Hypertension: A Population‐Based Study

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT The stress hyperglycemia ratio (SHR), a novel marker reflecting relative hyperglycemia, has been increasingly recognized for its prognostic value in cardiovascular and metabolic diseases. However, its association with early renal damage in hypertensive patients remains underexplored.
Kai‐Jun Zhang   +5 more
wiley   +1 more source

Development, characterization & invivo evaluation of proniosomal based transdermal delivery system of Atenolol

open access: yesFuture Journal of Pharmaceutical Sciences, 2018
The potential of proniosomes as a transdermal drug delivery system for Atenolol was investigated by encapsulating the drug in various formulations of proniosomal gel composed of various ratios of sorbitan fatty acid esters, cholesterol, lecithin prepared
S. Ramkanth   +5 more
doaj   +1 more source

The Application of Telemedicine in Surgery

open access: yesMed Research, EarlyView.
This figure provides an overview of the content presented in this article. Telemedicine is integrated throughout the entire surgical workflow, with distinct applications across the preoperative, intraoperative, and postoperative phases. These applications are enabled by a suite of supporting technologies, while the associated implementation challenges ...
Yufan Yang   +8 more
wiley   +1 more source

Recent Trends in Metabolomics by NMR Spectroscopy

open access: yesAngewandte Chemie, Volume 138, Issue 24, 8 June 2026.
AI tools were applied to analyze more than 5 000 publications indexed in Scopus (2018–2025), identifying key trends and research directions in NMR‐based metabolomics. The artificial intelligence‐assisted workflow classified papers into six main fields of application, human health, food and nutrition, veterinary science, plants, environment, and ...
Giorgio Di Paco   +6 more
wiley   +2 more sources

Vesicular Emulgel Based System for Transdermal Delivery of Insulin: Factorial Design and in Vivo Evaluation

open access: yesApplied Sciences, 2020
Transdermal delivery of insulin is a great challenge due to its poor permeability through the skin. The aim of the current investigation was to evaluate the prospective of insulin loaded niosome emulgel as a noninvasive delivery system for its ...
Tamer M. Shehata   +8 more
doaj   +1 more source

Printing to Fight Antimicrobial Resistance Through Nano/Microstructured Platforms

open access: yesThe Chemical Record, EarlyView.
Additive manufacturing enables the rational design of structured antimicrobial platforms across multiple length scales, from nanofibrous scaffolds and droplet microreactors to 3D and 4D printed constructs. By engineering confinement, interfacial chemistry, and stimuli‐responsive release, these systems exert localized action through complementary ...
Giorgia Puleo   +11 more
wiley   +1 more source

Preparation and characterization of a metered dose transdermal spray for testosterone

open access: yesActa Pharmaceutica Sinica B, 2013
The objective of the present work was to develop a metered dose transdermal spray (MDTS) formulation for transdermal delivery of testosterone and to characterize its efficacy. Testosterone release from a series of formulations was assessed in vitro. Skin
Wangding Lu   +4 more
doaj   +1 more source

Microplastics and the Endocrine–Metabolic Interface: Novel Diagnostic Tools Targeting Thyroid–Adipose Axis

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Microplastics (MPs) have been identified as major environmental contaminants that can affect organisms directly and act as carriers of particles and chemical additives, thereby aggravating endocrine networks that coordinate metabolic homeostasis.
Sunday Amos Onikanni   +10 more
wiley   +1 more source

Synergistic effect of iontophoresis and chemical enhancers on transdermal permeation of tolterodine tartrate for the treatment of overactive bladder

open access: yesInternational Brazilian Journal of Urology, 2013
Purpose The objective of the study was to evaluate the synergistic transdermal permeation effect of chemical enhancers and iontophoresis technique on tolterodine tartrate (TT) transdermal gel and to evaluate its pharmacokinetic properties.
D. Prasanthi, P. K. Lakshmi
doaj   +1 more source

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