Drug‐coated balloons: From conventional designs to next‐generation innovations in vascular therapy
BMEMat, EarlyView.This review traces the evolution of drug‐coated balloons (DCBs) from conventional designs to next‐generation platforms. We highlight innovations in balloon engineering, coating technologies, and therapeutic agents that enhance localized drug delivery while addressing challenges in efficiency, safety, and biocompatibility for vascular and emerging non ...
Lu Zhang +5 more
wiley +1 more source
Drug Design, Development and Therapy, 2018 Muhammad Rouf Akram,1 Mahmood Ahmad,1 Asad Abrar,1 Rai Muhammad Sarfraz,2 Asif Mahmood3 1Faculty of Pharmacy & Alternative Medicine, The Islamia University of Bahawalpur, Bahawalpur, Pakistan; 2Faculty of Pharmacy, University of Sargodha, Sargodha ...
Akram MR +4 more
doaj
Učinci adheziva osjetljivih na tlak i kemijskih promotora na permeaciju fentanila kroz kožu štakora [PDF]
, 2006 Drug-in-adhesive patches (DIAPs) of fentanyl were formulated using various pressure sensitive adhesives (PSAs) and various chemical permeation enhancers (CPEs).
AMIR MEHDIZADEH +3 more
core +1 more source
Topical delivery of hexamidine [PDF]
, 2016 Hexamidine diisethionate (HEX D) has been used for its biocidal actions in topical preparations since the 1950s. Recent data also suggest that it plays a beneficial role in skin homeostasis.
Hadgraft, J +5 more
core +1 more source
BMEMat, EarlyView.TCPL, a transfersome with Tween 80 and PEI, enables efficient transdermal siNF‐κB delivery, resolving PEI's toxicity issue. It promotes lysosomal escape and effective transfection, silences NF‐κB, modulates immunity, and inhibits angiogenesis, alleviating psoriasis. With good biocompatibility, TCPL holds strong clinical translation potential. Schematic
Hui Xing +6 more
wiley +1 more source
Current and evolving approaches for improving the oral permeability of BCS Class III or analogous molecules [PDF]
, 2016 The Biopharmaceutics Classification System (BCS) classifies pharmaceutical compounds based on their aqueous solubility and intestinal permeability. The BCS Class III compounds are hydrophilic molecules (high aqueous solubility) with low permeability ...
Dave, Vivek S +4 more
core +2 more sources
Fish Scales: A Multifunctional Biomaterial from Nature
ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.Fish scales demonstrate nature's solution to impact protection through overlapping multilayered architecture. This biological design combines mineralized surfaces with collagen networks to achieve both flexibility and fracture resistance. The structural principles inspire advanced protective materials and biomedical implants, where damage tolerance ...
Liyao Dong, Xiaojie Sun, Xiguang Chen
wiley +1 more source
Enhanced delivery of hydrophilic peptides in vitro by transdermal microneedle pretreatment
Acta Pharmaceutica Sinica B, 2014 The aims of this study were to investigate the utility of solid microneedle arrays (150 µm in length) in enhancing transdermal delivery of peptides and to examine the relationship between peptide permeation rates and D2O flux.
Suohui Zhang, Yuqin Qiu, Yunhua Gao
doaj +1 more source
Pengaruh Kombinasi Asam Oleat Dan Minyak Atsiri Daun Cengkeh (Syzygium Aromaticum L.) Sebagai Permeation Enhancer Terhadap Karakter Fisik Dan Pelepasan Ketoprofen Dari Matriks Patch Transdermal [PDF]
, 2015 Ketoprofen adalah obat antiinflamasi non-steroid yang dapat menimbulkan iritasi pada saluran gastrointestinal, sehingga diperlukan jalur pemberian alternatif yaitu dengan patch transdermal.
I, S. E. (Setyawan) +2 more
core
Fucoxanthin-Containing Cream Prevents Epidermal Hyperplasia and UVB-Induced Skin Erythema in Mice [PDF]
, 2018 Microalgae represent a source of bio-active compounds such as carotenoids with potent anti-inflammatory and antioxidant properties. We aimed to investigate the effects of fucoxanthin (FX) in both in vitro and in vivo skin models.
Cózar Bernal, María José +6 more
core +1 more source