Transdermal delivery of testosterone [PDF]
, 2015 Male hypogonadism has been treated with exogenous testosterone since the 1930s. The early transdermal patches of testosterone became available in the 1980s with gel and solution preparations following subsequent decades.
Hadgraft, J, Lane, ME
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SERS‐Based Nano‐ and Microsystems Toward Biomedical Applications
Small, EarlyView.This review provides a current overview of nano‐ and microscale SERS‐based devices, encompassing all aspects from material design to practical applications. We highlight controlled SERS‐active architectures, including patterned substrates, nanorods, microspheres, micromotors, and microneedles, as well as combinations of these microfluidic systems.
Gohar Soufi +14 more
wiley +1 more source
The Development of Transdermal Piroxicam Using HPMC Matrices With PVP K-30 as a Penetration Enhancer [PDF]
, 2006 The physicochemical properties such as solubility, partition coefficient, and membrane permeability of a drug are required for formulating and estimating drugs absorption that pass through biological membranes.
Aryani, Ni Luh Dewi
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Application of the Aqueous Porous Pathway Model to Quantify the Effect of Sodium Lauryl Sulfate on Ultrasound-Induced Skin Structural Perturbation [PDF]
, 2010 This study investigated the effect of sodium lauryl sulfate (SLS) on skin structural perturbation when utilized simultaneously with low-frequency sonophoresis (LFS).
Baris E. Polat +35 more
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Artificial Organs, EarlyView.eOGO is an uncommon adverse event in patients on long‐term LVAD support. Thirty‐one eOGO patients were identified in a single‐centre HM3 implantation program. Twenty patients underwent percutaneous stenting. This treatment resulted in immediate LVAD flow improvement and yielded satisfactory quality‐of‐life results, with 62.5% patients assigned a fair ...
Anna Huang +14 more
wiley +1 more source
Pengaruh Kombinasi Asam Oleat dan Minyak Atsiri Bunga Kamboja Cendana (Plumeria Alba) sebagai Permeation Enhancer terhadap Karakter Fisik dan Pelepasan Ketoprofen dari Matriks Patch Transdermal [PDF]
, 2015 Ketoprofen adalah obat antiinflamasi non-steroid yang dapat menimbulkan iritasi pada saluran gastrointestinal, sehingga diperlukan jalur pemberian alternatif yaitu dengan patch transdermal.
Budiputra, D. K. (D) +2 more
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Enhancing the transdermal delivery of rigid nanoparticles using the simultaneous application of ultrasound and sodium lauryl sulfate [PDF]
, 2010 The potential of rigid nanoparticles to serve as transdermal drug carriers can be greatly enhanced by improving their skin penetration. Therefore, the simultaneous application of ultrasound and sodium lauryl sulfate (referred to as US/SLS) was evaluated ...
Blankschtein, Daniel +3 more
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Cancer pain: current practice and emerging targets
British Journal of Pharmacology, EarlyView.Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye +5 more
wiley +1 more source
Effect of Drug Loading Method and Drug Physicochemical Properties on the Material and Drug Release Properties of Poly (Ethylene Oxide) Hydrogels for Transdermal Delivery [PDF]
, 2017 Novel poly (ethylene oxide) (PEO) hydrogel films were synthesized via UV cross-linking with pentaerythritol tetra-acrylate (PETRA) as cross-linking agent. The purpose of this work was to develop a novel hydrogel film suitable for passive transdermal drug
Dodou, Kalliopi, Wong, Rachel Shet Hui
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Physiological Basis of Sex Differences in Human Performance and Exercise‐Associated Pathology
Clinical Endocrinology, EarlyView.ABSTRACT The presence of sex differences in human physical performance is well‐established and shaped by distinct endocrine, anatomical and physiological mechanisms. Despite sustained advances, our understanding of how inherent biological factors drive variations in exercise capacity and related pathologies is still developing.
David A. Holdsworth +7 more
wiley +1 more source