International Journal of Nanomedicine, 2011 Ji-Hui Zhao, Li Ji, Hui Wang, Zhi-Qiang Chen, Yong-Tai Zhang, Ying Liu, Nian-Ping FengSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, People's Republic of ChinaObjective: To deliver 2,3,5,6-tetramethylpyrazine ...
Zhao JH +6 more
doaj
A comparative study of the in vitro permeation of ibuprofen in mammalian skin, the PAMPA model and silicone membrane [PDF]
, 2016 Human skin remains the membrane of choice when conducting in vitro studies to determine dermal penetration of active pharmaceutical ingredients or xenobiotics. However there are ethical and safety issues associated with obtaining human tissue.
Avnish Patel +6 more
core +1 more source
Microneedles for the treatment of migraine and orofacial pain: A narrative review
Headache: The Journal of Head and Face Pain, EarlyView.Abstract Background Migraine is a common neurological disorder and a primary headache condition. Despite its central origin, migraine pain may be referred to the orofacial region via trigeminal pathways, resulting in phenotypic overlap with other orofacial pain (OFP) conditions.
Baicheng Cao +6 more
wiley +1 more source
Iontophoretic Permeation of Lisinopril at Different Current Densities and Drug Concentrations [PDF]
Advanced Pharmaceutical Bulletin, 2012 Purpose: The purpose of the present work was to assess iontophoretic permeation of Lisinopril at different current densities and concentrations for development of patient-controlled active transdermal system.
Ashish Jain, Satish Nayak, Vandana Soni
doaj
Ginger Extract-Loaded Transethosomes for Effective Transdermal Permeation and Anti-Inflammation in Rat Model. [PDF]
Int J Nanomedicine, 2023 Hassan AS +3 more
europepmc +1 more source
An investigation of some factors affecting transdermal permeation
, 1985 Factors affecting transdermal permeation were investigated using Differential Thermal Anlaysis (DTA) and in vitro penetration studies of neonatal rat stratum corneum (s.c.), with radiolabelled propanol and hexanol as penetrants. Thermogravimetric Analysis, Thin-Layer Chromatography (TLC) and Infrared Spectroscopy were used to provide additional ...
openaire +2 more sources
Penetration enhancement effects of topically applied crosslinked hyaluronic acid
International Journal of Cosmetic Science, EarlyView.Cross‐linked hyaluronic acid (HA) was demonstrated to enhance the topical delivery of a variety of hydrophilic actives into the skin. This phenomenon was observed for both small molecules and macromolecules, the latter of which was analysed with MALDI mass spectrometry imaging (MALDI‐MSI).
Aaron Cohen +7 more
wiley +1 more source
Enhancement of transdermal permeation of cannabinoids and their pharmacodynamic evaluation in rats. [PDF]
Int J Pharm, 2022 Salau O, Bagde A, Kalvala A, Singh M.
europepmc +1 more source
Rationalising polymer selection for supersaturated film forming systems produced by an aerosol spray for the transdermal delivery of methylphenidate [PDF]
, 2017 Film forming systems offer a number of advantages for topical and transdermal drug delivery, in particular enabling production of a supersaturated state which can greatly improve drug absorption and bioavailability.
Brown, Marc B. +4 more
core +3 more sources
Pharmacokinetics of Topical Administration of Altrenogest in Mares and Implications for Human Health
Journal of Veterinary Pharmacology and Therapeutics, EarlyView.ABSTRACT Altrenogest is a synthetic progestogen widely used in equine reproductive management. Adverse effects to altrenogest have been reported in people with cutaneous exposure reported as the highest exposure pathway. Despite these reports, there has been no quantitative research to determine the capacity for altrenogest to be absorbed through skin.
Jaymie Loy +5 more
wiley +1 more source