Evaluation of in vitro transdermal permeation, mass spectrometric imaging, and in vivo analgesic effects of pregabalin using a pluronic lecithin organogel formulation in mice. [PDF]
Nagao M +9 more
europepmc +1 more source
Design Considerations for Polymer–Deep Eutectic Solvent Hybrid Systems for Transdermal Drug Delivery
Deep eutectic solvents (DESs) act as tunable, green excipients that modulate polymer structure–property relationships to enhance drug solubility, skin permeation, stability, and controlled release. Through hydrogen‐bond interactions, DES–polymer hybrid systems enable improved transdermal performance, offering a rational, design‐driven platform for ...
Madhavi Kailas Kapale +3 more
wiley +1 more source
Abstract BACKGROUND Curcumin is a naturally derived polyphenol known for its potent biological properties. Its therapeutic potential, however, is hindered by low bioavailability. Nanostructured lipid carriers (NLCs) have emerged as advanced delivery systems to overcome such limitations. Natural deep eutectic solvents (NADESs) have garnered attention as
Kyriaki Safari +5 more
wiley +1 more source
Overview of pharmaceutical nanocarriers in diabetes, illustrating applications of nanotechnology including enhanced drug and targeted drug delivery and nanosensors for glucose monitoring and diagnosis. ABSTRACT Pediatric type 2 diabetes mellitus (T2DM) is rapidly emerging as a critical global health concern, driven largely by rising childhood obesity ...
Nnamdi Ikemefuna Okafor +2 more
wiley +1 more source
Optimizing and Evaluating the Transdermal Permeation of Hydrocortisone Transfersomes Formulation Based on Digital Analysis of the In Vitro Drug Release and Ex Vivo Studies. [PDF]
Abdelwahd A, Abdul Rasool BK.
europepmc +1 more source
Piezo‐Coupling Effects in Smart Polymers: Toward Ultrasensitive Sensing and Biomedical Applications
Piezo‐coupling effects are the foundational factors for the development of multifunctional and self‐powered platforms. Central to this advancement is the use of stimuli‐responsive smart polymers, which offer mechanical flexibility, biocompatibility, and simplified structural complexity with improved sensitivity and energy efficiency.
Duc Khanh Tran +6 more
wiley +1 more source
Transkarbam 12 and caffeine transdermal permeation from oleocreams. 2. [PDF]
In theoretical part of this work, the skin barrier function and transdermal permeation enhancers (with focus on Transkarbam 12, T12) were reviewed. In following experimental part, the acceleration effect of various concentrations of Transkarbam 12 (T12 ...
Dvořáková, Pavla
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Transdermal Permeation in Vitro Study of Creams Containing Transkarbam 12 [PDF]
Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department of Department of Pharmaceutical Technology Candidate Mgr. Pavla Dvořáková Consultant Doc. RNDr. Pavel Doležal, CSc.
Dvořáková, Pavla
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Fish Scales: A Multifunctional Biomaterial from Nature
Fish scales demonstrate nature's solution to impact protection through overlapping multilayered architecture. This biological design combines mineralized surfaces with collagen networks to achieve both flexibility and fracture resistance. The structural principles inspire advanced protective materials and biomedical implants, where damage tolerance ...
Liyao Dong, Xiaojie Sun, Xiguang Chen
wiley +1 more source
Synthesis and evaluation of transdermal permeation enhancers based on terpenes [PDF]
Monika Kopečná Synthesis and evaluation of transdermal permeation enhancers based on terpenes Transdermal drug delivery has many advantages over the conventional routes of administration.
Kopečná, Monika
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