Results 61 to 70 of about 88,006 (229)

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

PREPARATION AND CHARACTERIZATION OF TOPICAL FORMULATIONS CONTAINING 6-O-ALKYL DERIVATIVES OF ASCORBIC ACID [PDF]

, 2009
Alkyl vitamin C derivatives (ASCn) are amphiphilic molecules having physicochemical properties that depend on the alkyl chain length. The derivatives with low molecular weight (n < 11) have enough aqueous solubility to produce self-assemblies at room ...
SAINO, VERONICA
core   +1 more source

Assessment of Finite and Infinite Dose In Vitro Experiments in Transdermal Drug Delivery

Pharmaceutics, 2021
Penetration, usually with finite dosing, provides data about the total active amount in the skin and permeation, being the most used methodology, usually with infinite dosing, leads to data about pharmacokinetic parameters.
Luisa Coderch, Ilaria Collini, Victor Carrer, Clara Barba, Cristina Alonso   +4 more
doaj   +1 more source

Penetration of Chlorhexidine into Human Skin [PDF]

, 2008
This study evaluated a model of skin permeation to determine the depth of delivery of chlorhexidine into full-thickness excised human skin following topical application of 2% (wt/vol) aqueous chlorhexidine digluconate.
Karpanen, T. J., Conway, Barbara R, Karpanen, Tarja J., Worthington, Tony, Hilton, Anthony C., Elliott, Tom S.J., Worthington, T., Elliott, T. S. J., Lambert, Peter A., Conway, Barbara R., Lambert, P. A., Hilton, A. C.   +11 more
core   +1 more source

Patterned Screen‐Printing Process for Substrate‐Free and Scalable Hyaluronic Acid Microneedle Arrays

Advanced Materials Technologies, EarlyView.
A substrate‐free microneedle array comprising a hybrid hyaluronic acid ink was fabricated via a scalable screen‐printing process for flexible transdermal drug delivery. Defect‐free mold filling was achieved using a vacuum‐assisted jig and a delayed drying system, and the use of this versatile platform for multi‐drug patterning and ex vivo skin ...
Sanghyun Ahn, Jaeho Kim, SeungHyun Park, WonHyoung Ryu   +3 more
wiley   +1 more source

Effect of Ultrasound on Transdermal Permeation of Diclofenac

European Journal of Inflammation, 2006
During the last two decades the effects of ultrasound on the transdermal permeability to a wide variety of drugs have been extensively investigated. There is still some uncertainty regarding the mechanisms involved in ultrasonic permeation enhancement, thus we investigated the effect of ultrasonic treatment on the transdermal permeation of the NSAID ...
Van der Bijl P, Basson E, Van Eyk AD, Seifart HI   +3 more
openaire   +2 more sources

Intelligent Micro/Nanorobots for Targeted Interventional Therapy: From Bench to Clinic

Advanced Robotics Research, EarlyView.
Zirui Zhang et al. reviewed the application and challenges of mobile nanomachines in interventional therapy. By converting exogenous energy, including chemical, magnetic, optical, and ultrasonic sources, into mechanical forces, micro/nanorobots (MNRs) enable precise actuation at unprecedented scales. Evolving far beyond traditional drug delivery, these
Zirui Zhang, Yu Dong, Yongsheng Du, Rui Gao, Lin Zhang, Fei Tong   +5 more
wiley   +1 more source

Permeability Enhancement of Methotrexate Transdermal Gel using Eucalyptus oil, Peppermint Oil and Olive Oil(Conference Paper )#

Iraqi Journal of Pharmaceutical Sciences, 2022
Objective: the idea of this study to improve transdermal permeability of Methotrexate using eucalyptus oil, olive oil and peppermint oil as enhancers. Method: eucalyptus oil (2% and 4%), peppermint oil (2% and 4%) and olive oil (2% and 4%) all used as ...
Jamal Ali Ashoor, Jinan M. Mohsin, Hussein Mohammed Mohsin, Basam W. Mahde, Mowafaq M. Gareeb   +4 more
doaj   +1 more source

Making Sweat Measurable: Induction, Sampling, and Refreshment in Wearable Biofluid Sensing

Advanced Science, EarlyView.
Wearable sweat sensing relies not only on chemical detection but also on controlled biofluid management. This Review integrates sweat physiology, induction strategies, and microfluidic sampling architectures, demonstrating how flux, transport, and refreshment shape measurement reliability.
Soyoung Shin, Wei Gao
wiley   +1 more source

Ionic liquid-iontophoresis mediates transdermal delivery of sparingly soluble drugs

Drug Delivery
Low solubility restricted transdermal penetration of drugs. We aimed to develop a novel ionic liquid-iontophoresis (IL-IS) technology and assess their efficacy and primary factors in facilitating transdermal drug delivery.
Wenyan Gao, Wenmin Xing, Zhan Tang, Qiao Wang, Wenying Yu, Qi Zhang   +5 more
doaj   +1 more source