Results 61 to 70 of about 17,365 (234)

Ionic liquid-iontophoresis mediates transdermal delivery of sparingly soluble drugs

Drug Delivery
Low solubility restricted transdermal penetration of drugs. We aimed to develop a novel ionic liquid-iontophoresis (IL-IS) technology and assess their efficacy and primary factors in facilitating transdermal drug delivery.
Wenyan Gao, Wenmin Xing, Zhan Tang, Qiao Wang, Wenying Yu, Qi Zhang   +5 more
doaj   +1 more source

Experimental Design Based Optimization and Ex Vivo Permeation of Desmopressin Acetate Loaded Elastic Liposomes Using Rat Skin

Pharmaceutics, 2021
The study aimed to develop elastic-liposome-based transdermal delivery of desmopressin acetate for enhanced permeation to control enuresis, central diabetes insipidus, and traumatic injury. Elastic liposomes (ELs)-loaded desmopressin acetate was prepared,
Mohammad A. Altamimi, Afzal Hussain, Sultan Alshehri, Syed Sarim Imam   +3 more
doaj   +1 more source

N-alkylamides : from plant to brain [PDF]

, 2014
Background: Plant N-alkylamides (NAAs) are bio-active compounds with a broad functional spectrum. In order to reach their pharmacodynamic targets, they have to overcome several barriers of the body in the absorption phase.
De Spiegeleer, Bart, Joshi, Tanmayee, Taevernier, Lien, Tatke, Pratima, Verbeke, Frederick, Veryser, Lieselotte, Wynendaele, Evelien   +6 more
core  

Multi‐Functional Adaptive Interfaces for Next‐Generation Wearable and Implantable Bioelectronics

Advanced Science, EarlyView.
Adaptive Biointerfaces: A comprehensive overview of next‐generation bioelectronics is presented, highlighting mechano‐adaptive and biophysiologically adaptive interfaces that enable stable, long‐term integration with living tissues. As illustrated in the image, adaptive interface strategies, including mechano‐adaptivity (e.g., injectability, shape ...
Jinhong Park, Junyoung Ha, Do Gyun Kim, Soo‐Hong Lee, Hyun‐Do Jung, Ja Hoon Koo, Gi Doo Cha, Dong Chan Kim   +7 more
wiley   +1 more source

Development of Novel Formulations to Enhance in Vivo Transdermal Permeation of Tocopherol

Acta Pharmaceutica, 2014
Tocopherol represents a big challenge for transdermal permeation owing to its extreme hydrophobicity and large molecular mass. The aim of the present study was to develop alpha-tocopherol (T) topical formulations and evaluate their ex vivo and in vivo ...
Nada Aly H., Zaghloul Abdelazim A., Hedaya Mohsen M., Khattab Ibrahim S.   +3 more
doaj   +1 more source

Chronic Disease Monitoring Using Advanced Compliant Materials for Bioelectronics

Advanced Electronic Materials, EarlyView.
Compliant bioelectronic systems enable continuous monitoring of chronic disease through soft, stretchable materials and tissue‐conformal designs that support stable electrophysiological, mechanical, and biochemical sensing. Integration of diverse sensing modalities with thoughtful material selection, device architectures, and advanced fabrication ...
Han Kim, Mabel Bartlett, Liyang Wang, Karl Bates, Mengdi He, Myungbo Kim, Carmel Majidi, Tzahi Cohen‐Karni   +7 more
wiley   +1 more source

Nanoformulation mediated transdermal delivery of anti-diabetic drugs: an updated review

Intelligent Pharmacy, 2023
Diabetes mellitus is a concern of disorder globally and which is increasing continuously. Diabetic complications lead to physical, mental and societal issues to patients. Oral medications are being prescribed but these have problems like frequent dosing,
Mohd Hussain, Abdul Hafeez, Shom Prakash Kushwaha   +2 more
doaj   +1 more source

Penetration enhancing effect of phytoceramides [PDF]

, 2012
Ceramides are essential components in the stratum corneum barrier function. Different classes of ceramides are present in human skin, differing in the nature of sphingosine and acyl moieties with respect to chain length, degree of saturation and the ...
Boonen, Jente, De Spiegeleer, Bart, Guillaume, Joren, Risseeuw, Martijn, Van Calenbergh, Serge, Veryser, Lieselotte   +5 more
core   +1 more source

Topical formulations of miltefosine for cutaneous leishmaniasis in a BALB/c mouse model. [PDF]

, 2016
UNLABELLED: Cutaneous leishmaniasis (CL) is caused by several species of the protozoan parasite Leishmania and affects approximately 10 million people worldwide.
Croft, Simon L, Murdan, Sudaxshina, Van Bocxlaer, Katrien, Yardley, Vanessa   +3 more
core   +2 more sources

Autonomous AI‐Driven Design for Skin Product Formulations

Advanced Intelligent Discovery, EarlyView.
This review presents a comprehensive closed‐loop framework for autonomous skin product formulation design. By integrating artificial intelligence‐driven experiment selection with automated multi‐tiered assays, the approach shifts development from trial‐and‐error to intelligent optimisation.
Yu Zhang, Yongrui Xiao, Chunlin Chen, Dimitrios Tsaoulidis, Kai Yang, Tao Chen   +5 more
wiley   +1 more source