Results 21 to 30 of about 88,006 (229)

Ionic-liquid-facilitated transdermal absorption of lidocaine hydrochloride. [PDF]

open access: yesPLoS ONE
The increasing worldwide need for analgesics, along with patients' aversion to injectable anesthetics and limited compliance, highlights the necessity for noninvasive local anesthesia.
Xiaoting Ma   +3 more
doaj   +2 more sources

EFFECT OF ESSENTIAL OILS ON TRANSDERMAL PERMEATION OF METOPROLOL SUCCINATE [PDF]

open access: yesBulletin of Pharmaceutical Sciences. Assiut University, 2021
The objective of the present study was to prepare a matrix-type transdermal drug delivery system containing metoprolol succinate and to evaluate the effect of essential oils on transdermal permeation of drug.
B. N. Suhagia   +5 more
doaj   +1 more source

Development of an optimised application protocol for sonophoretic transdermal delivery of a model hydrophilic drug [PDF]

open access: yes, 2011
It has now been known for over a decade that low frequency ultrasound can be used to effectively enhance transdermal drug penetration - an approach termed sonophoresis.
Abdul, Rasool   +2 more
core   +4 more sources

The enantioselective enhancing effect and mechanistic insights of chiral enhancers in transdermal drug delivery

open access: yesAsian Journal of Pharmaceutical Sciences, 2023
Overlook of chiral consideration in transdermal drug delivery increases administrated dose and risk of side effects, decreasing therapeutical effects. To improve the transdermal delivery efficiency of eutomer, this work focused on investigating the law ...
Yang Zhang   +9 more
doaj   +1 more source

Enhanced Transdermal Delivery of Bisoprolol Hemifumarate via Combined Effect of Iontophoresis and Chemical Enhancers: Ex Vivo Permeation/In Vivo Pharmacokinetic Studies

open access: yesPharmaceutics, 2021
Bisoprolol hemifumarate (BH) is an antihypertensive drug that is used as first-line treatment for chronic hypertension and angina pectoris. Our study was performed to enhance the transdermal delivery of BH, a hydrophilic drug active with high molecular ...
Mahmoud H. Teaima   +5 more
doaj   +1 more source

Jojoba oil-based microemulsion for transdermal drug delivery

open access: yesResearch in Pharmaceutical Sciences, 2021
Background and purpose: Microemulsions are gaining an increased interest in transdermal drug delivery. Microemulsions are stable, easy to prepare, and provide high solubilizing capacity for various drugs.
Shereen Mashhour Assaf   +4 more
doaj   +1 more source

A comprehensive review on invasomal carriers incorporating natural terpenes for augmented transdermal delivery

open access: yesFuture Journal of Pharmaceutical Sciences, 2022
Background Transdermal drug delivery is one of the most widely used drug administration routes, which offer several advantages over other routes of drug delivery.
Bhumika Kumar   +3 more
doaj   +1 more source

Study of the permeation-promoting effect and mechanism of solid microneedles on different properties of drugs

open access: yesDrug Delivery, 2023
In transdermal drug delivery systems, the physicochemical properties of the drug affect its percutaneous permeability. However, whether the physicochemical properties of drugs change their transdermal permeability in the presence of pores in the presence
Huahua Li   +10 more
doaj   +1 more source

Pharmacokinetic studies for the development of transdermal drug delivery systems [PDF]

open access: yes, 2007
PhDThis thesis mainly describes a series of Phase I pharmacokinetic studies conducted on the TDS®d elivery systemw hich combinedw ith lidocaine,t estosteronea, nd a new drug, Melanotan-I for the transdermal drug delivery.
Chik, Zamri
core   +4 more sources

Effect of Microneedle Type on Transdermal Permeation of Rizatriptan [PDF]

open access: yesAAPS PharmSciTech, 2017
The present study was aimed to investigate the effect of salient microneedle (MN) geometry parameters like length, density, shape and type on transdermal permeation of rizatriptan (RIZ). Studies were carried out using two types of MN devices viz. AdminPatch® arrays (ADM) (0.6, 0.9, 1.2 and 1.5 mm lengths) and laboratory-fabricated polymeric MNs (PMs ...
Chandrateja, Uppuluri   +7 more
openaire   +2 more sources

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