Results 21 to 30 of about 93,495 (232)
Drug Delivery, 2023 In transdermal drug delivery systems, the physicochemical properties of the drug affect its percutaneous permeability. However, whether the physicochemical properties of drugs change their transdermal permeability in the presence of pores in the presence
Huahua Li +10 more
doaj +1 more source
The Development of Transdermal Piroxicam Using HPMC Matrices With PVP K-30 as a Penetration Enhancer [PDF]
, 2006 The physicochemical properties such as solubility, partition coefficient, and membrane permeability of a drug are required for formulating and estimating drugs absorption that pass through biological membranes.
Aryani, Ni Luh Dewi
core +2 more sources
Temperature influencing permeation pattern of alfuzosin: An investigation using DoE
Medicina, 2015 Background and objective: There has been relatively little investigation of the effect of temperature on skin permeation compared to other methods of penetration enhancement.
Satyanarayan Pattnaik +4 more
doaj +1 more source
Effect of microneedles on transdermal permeation enhancement of amlodipine [PDF]
Drug Delivery and Translational Research, 2017 The present study aimed to investigate the effect of microneedle (MN) geometry parameters like length, density, shape and type on transdermal permeation enhancement of amlodipine (AMLO). Two types of MN devices viz. AdminPatch® arrays (ADM) (0.6, 1.2 and 1.5 mm lengths) and laboratory-fabricated polymeric MNs (PM) of 0.6 mm length were employed. In the
Buchi N, Nalluri +6 more
openaire +2 more sources
Strategies To Enhance Transdermal Drug delivery [PDF]
المجلة العراقية للصيدلة, 2021 Background: Transdermal drug delivery system (TDDS) is a promising delivery system that provides controlled drug release at a predetermined time. It has many advantages such as bypassing first-pass effect, increase patient convenience by providing single
Mais Saadallah, Omar Hamid
doaj +1 more source
Effect of continuous phase drug concentration, evaporation and partitioning on transdermal drug permeation kinetics with lipophilic vehicles [PDF]
, 2008 In this work the dependence of transdermal drug permeation kinetics on continuous phase drug concentration, partitioning between formulation phases, partitioning between stratum corneum and continuous oil phase and evaporation of volatile formulation ...
Reiser, Miriam Regina Luise
core +1 more source
Pharmaceutics, 2023 Retinoid-based drugs, while effective, are associated with systemic toxicity. Topical alternatives offer a safer option, and tazarotene, a third-generation synthetic retinoid, holds promise.
Helena Hamzehpour +5 more
doaj +1 more source
Effect of Microneedle Type on Transdermal Permeation of Rizatriptan [PDF]
AAPS PharmSciTech, 2017 The present study was aimed to investigate the effect of salient microneedle (MN) geometry parameters like length, density, shape and type on transdermal permeation of rizatriptan (RIZ). Studies were carried out using two types of MN devices viz. AdminPatch® arrays (ADM) (0.6, 0.9, 1.2 and 1.5 mm lengths) and laboratory-fabricated polymeric MNs (PMs ...
Chandrateja, Uppuluri +7 more
openaire +2 more sources
Non-invasive Transdermal Delivery of Human Insulin Using Ionic Liquids: In vitro Studies
Frontiers in Pharmacology, 2020 In this research project, synthesis and characterization of ionic liquids and their subsequent utilization as facilitators of transdermal delivery of human insulin was pursued.
Ludmilla R. Jorge +11 more
doaj +1 more source
Electret Enhances Transdermal Drug Permeation
Biological and Pharmaceutical Bulletin, 2008 Electrets are polymeric discs that carry semi permanent electrostatic charge. These provide electrostatic potentials in the range of 500 to 3,000 V. In the current work, the effect of electret exposure on the skin permeability was investigated. Transdermal transport studies were carried out across porcine epidermis in Franz diffusion cells.
Narasimha Sathyanarayana Murthy, Narasimha Sathyanarayana +2 more
openaire +2 more sources