Solid Lipid Nanoparticles: A Potential Approach for Dermal Drug Delivery [PDF]
, 2014 Solid lipid nanoparticles (SLNs) have attracted increasing attention during recent years. Due to their unique size dependent properties, lipid nanoparticles offer possibilities to develop new therapeutics.
Conway, Barbara R, Kakadia, Pratibha G.
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Pharmaceutics, 2021 The exponentially mounting cases of herpes simplex virus infection or cold sores have become a serious global concern. Acyclovir (ACV) and garlic oil (GO)-loaded lipid nanocarrier could be a promising therapeutic approach in alleviating cold sores, as ...
Alshaimaa M. Almehmady, Sarah A. Ali
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N-Alkylmorpholines: Potent Dermal and Transdermal Skin Permeation Enhancers [PDF]
Pharmaceutics, 2021 Transdermal drug delivery is an attractive non-invasive method offering numerous advantages over the conventional routes of administration. The main obstacle to drug transport is, however, the powerful skin barrier that needs to be modulated, for example, by transdermal permeation enhancers.
Kristýna Dvořáková +3 more
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Predicting Skin Permeability by means of Computational Approaches : Reliability and Caveats in Pharmaceutical Studies [PDF]
, 2019 © 2019 American Chemical Society.The skin is the main barrier between the internal body environment and the external one. The characteristics of this barrier and its properties are able to modify and affect drug delivery and chemical toxicity parameters.
Almerico, Anna Maria +5 more
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Investigation of transdermal permeation of atorvastatinloaded microemulsions
Tropical Journal of Pharmaceutical Research, 2022 Purpose: To develop microemulsions containing atorvastatin for transdermal application, which will improve the bioavailability and reduce the side effects associated with the oral administration of atorvastatin.Methods: Atorvastatin-loaded microemulsions (MEs) were developed using tween 80 as a nonionic surfactant, isopropyl myristate, polyethylene ...
Alkrad, Jamal Alyoussef +3 more
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Influence of the Component Excipients on the Quality and Functionality of a Transdermal Film Formulation [PDF]
, 2015 The influence of formulation variables, i.e., a hydrophilic polymer (Methocel® E15) and a film-forming polymer (Eudragit® RL 100 and Eudragit® RS 100), on the physicochemical and functional properties of a transdermal film formulation was assessed ...
Atram, Sandip C. +5 more
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Optimization and Characterization of Chitosan Films for Transdermal Delivery of Ondansetron
Molecules, 2013 The aim of this study was to develop novel transdermal films of ondansetron HCl with high molecular weight chitosan as matrix polymer and 2-(2-ethoxy-ethoxy) ethanol (Transcutol®) as plasticizer. In this context, firstly the physicochemical properties of
Yıldız Özsoy +3 more
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The Relationship between Solubility and Transdermal Absorption of Tadalafil [PDF]
Advanced Pharmaceutical Bulletin, 2015 Purpose: The aim of this study was to find a relationship between drug solubility and its transdermal permeation and find the best vehicle composition to improve transdermal permeation of Tadalafil.
Hamed Hamishehkar +3 more
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The use of heat and chemical penetration enhancers to increase the follicular delivery of erythromycin to the skin [PDF]
, 2019 Copyright © 2019. Published by Elsevier B.V.The effect of heat on the follicular absorption of drugs into the skin has not previously been investigated.
Akomeah +42 more
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Accelerating topical anaesthesia using microneedles [PDF]
, 2017 Background/Aims: Topical anaesthetics reduce pain during venous access procedures in children. However, clinical use is hindered by a significant anaesthetic onset time.
Birchall, James +4 more
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