Results 91 to 100 of about 74,690 (303)

In Vivo Emergence of Podovirus Resistance via tarS Mutation During Phage-Antibiotic Treatment of Experimental MSSA Endocarditis

Viruses
Phage therapy shows promise as an adjunct to antibiotics for treating Staphylococcus aureus infections. We previously reported a combined flucloxacillin/two-phage cocktail treatment selected for resistance to podovirus phage 66 in a rodent model of ...
Jérémy Cherbuin, Jonathan Save, Emma Osswald, Grégory Resch   +3 more
doaj   +1 more source

A rapid and simple protocol for the isolation of bacteriophages from coastal organisms

MethodsX, 2019
This work details a protocol for recovering bacteriophages from intertidal sessile mussels and testing their lytic activity against pathogenic bacteria.
Alex Echeverría-Vega, Pablo Morales-Vicencio, Camila Saez-Saavedra, Felipe Gordillo-Fuenzalida, Rubén Araya   +4 more
doaj   +1 more source

Two novel bacteriophage genera from a groundwater reservoir highlight subsurface environments as underexplored biotopes in bacteriophage ecology

Scientific Reports, 2020
Although bacteriophages are central entities in bacterial ecology and population dynamics, there is currently no literature on the genomes of bacteriophages isolated from groundwater.
Ole Hylling, Alexander B. Carstens, Witold Kot, Martin Hansen, Horst Neve, Charles M. A. P. Franz, Anders Johansen, Lea Ellegaard-Jensen, Lars H. Hansen   +8 more
doaj   +1 more source

Transcription Factor Promiscuity Drives Regulatory Rewiring and Evolvability in Gene Networks in Bacteria

Advanced Science, EarlyView.
When a master transcription factor (TF) is lost, bacteria can rapidly rewire gene regulatory networks by co‐opting related regulators. Using experimental evolution in Pseudomonas fluorescens, we show that TF promiscuity (low‐level, non‐cognate binding) provides the raw material for rewiring. Successful co‐option follows a predictable hierarchy governed
Tiffany B. Taylor, Alan M. Rice
wiley   +1 more source

A Phage-Guided Route to Discovery of Bioactive Rare Actinomycetes [PDF]

, 2012
Bacteriophages have received attention as biological control agents since their discovery and recently their value as tools has been further emphasized in many different fields of microbiology. Particularly, in drug design and development programs, phage
Kurtboke, D I, D.I. Kurtböke, D.I. Kurtbke   +2 more
core   +1 more source

Presence of stx-encoding bacteriophages.

, 2021
Presence of stx-encoding bacteriophages.
Robin King (4026194), Carlos Adam Conte-Junior (4109803), Vinicius Silva Castro (11383949), Emmanuel Wihkochombom Bumunange (11383955), Tim McAllister (151974), Kim Stanford (171298), Rodrigo Ortega Polo (11383952), Eduardo Eustáquio de Souza Figueiredo (3122319)   +7 more
core   +1 more source

Study of the Activity of the Staphylococcus aureus Phage vB_SaS_GE1 Against MRSA Clinical Isolates and Its Impact on the Formation of Dual-Species Biofilms with P. aeruginosa

Viruses
Bacteriophage therapy is regarded as a promising alternative for treating and preventing antibiotic-resistant bacterial infections. Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most prevalent and difficult-to-treat pathogens.
Nino Grdzelishvili, Davit Lazviashvili, Aleksandra Kurowska, Krzysztof Jakub Pawlik, Łukasz Łaczmanski, Elene Kakabadze, Elene Zhuravliova, Nina Chanishvili, Nata Bakuradze   +8 more
doaj   +1 more source

Biofilm‐Binding Phages Enhance Biofilm Eradication by Synergistic Photothermal and Photodynamic Therapy

Advanced Science, EarlyView.
Engineered phage‐based trifunctional nanofibers are developed for synergistic biofilm eradication. Biofilm‐binding phages, armed with AuNPs and TCPP, serve as both warheads and scaffolds, endowing the phototherapy agents with biofilm‐anchoring ability. Upon light irradiation, AuNPs induce photothermal therapy, while TCPP generates 1O2 for photodynamic ...
Ying Cao, Tao Yang, Rui Wang, Hui‐Da Li, Xiao‐Yu Zhang, Feng Cheng, Ying Liu, Jian‐Hua Wang, Ting Yang, Chuanbin Mao   +9 more
wiley   +1 more source

THE USE OF BACTERIOPHAGES IN THE TREATMENT OF STAPHYLOCOCCAL INFECTION

Aim of study. The current rate of increase in the number of antimicrobial-resistant infections is poised to become the leading global cause of loss of human life.
Dmitri IUNAC, Lucia GALBEN, Greta BALAN, Alina FERDOHLEB, Elena CIOBANU   +4 more
core   +1 more source

Utilizing Bacteriophages to Manage Biofilm Infections on Medical Devices: A Systematic Review [PDF]

Medical device-related infections are deep-seated infections that are complex to treat owing to the emergence of antibiotic-resistant organisms. Bacteriophages are non-antibiotic tools that act as either an alternative or complementary option to ...
Pushkal Sinduvadi Ramesh, Nisha K. Rai, Veena A. Shetty   +2 more
core   +1 more source