Results 141 to 150 of about 187,845 (400)

Distinct genealogies for plasmids and chromosome [PDF]

, 2014
An earlier perspective on the diversity of conjugative elements in microbes [1] attempted to provide a broad audience with an introductory overview of the arcane biology of mobile genetic elements and their terminologies. It might well have been entitled
Achtman, Mark, Zhou, Zhemin
core   +2 more sources

Salvage Debridement, Antibiotics and Implant Retention (“DAIR”) With Local Injection of a Selected Cocktail of Bacteriophages: Is It an Option for an Elderly Patient With Relapsing Staphylococcus aureus Prosthetic-Joint Infection?

Open Forum Infectious Diseases, 2018
Local injection of a bacteriophages mix during debridement, antibiotics and implant retention (“DAIR”) was performed to treat a relapsing Staphylococcus aureus chronic prosthetic joint infection (PJI).
T. Ferry, G. Leboucher, C. Fèvre, Yannick Herry, A. Conrad, J. Josse, C. Batailler, C. Chidiac, M. Médina, S. Lustig, F. Laurent, Tristan Tristan Florent Thomas André François Patrick Flor Ferry Ferry Valour Perpoint Boibieux Biron Miailhe, T. Ferry, F. Valour, T. Perpoint, A. Boibieux, F. Biron, P. Miailhes, F. Ader, A. Becker, S. Roux, C. Triffault-Fillit, A. Conrad, A. Bosch, F. Daoud, J. Lippman, E. Braun, C. Chidiac, S. Lustig, E. Servien, R. Gaillard, A. Schneider, S. Gunst, C. Batailler, M. Fessy, J. Besse, Yannick Herry, A. Viste, P. Chaudier, C. Courtin, L. Louboutin, S. Martres, F. Trouillet, C. Barrey, E. Jouanneau, T. Jacquesson, A. Mojallal, F. Boucher, H. Shipkov, J. Château, F. Aubrun, Mikhail A. Dziadzko, C. Macabeo, F. Laurent, Laeticia Beraud, J. Josse, C. Kolenda, C. Dupieux, F. Craighero, L. Boussel, J. Pialat, I. Morelec, M. Janier, F. Giammarile, M. Tod, M. Gagnieu, S. Goutelle, Béatrice Grisi, C. Dananché, E. Mabrut   +69 more
semanticscholar   +1 more source

Multimodal Actuation and Environment Adaptive Strategies of Bio‐Inspired Micro/Nanorobots in Precision Medicine

Advanced Robotics Research, EarlyView.
An introduction for multidrive and environment‐adaptive micro/nanorobotics: design and fabrication strategies, intelligent actuation, and their applications. Various intelligent actuation approaches—magnetic, acoustic, optical, chemical, and biological—can be synergistically designed to enhance flexibility and adaptive behavior for precision medicine ...
Aiqing Ma, Han Gong, Jiacheng Ouyang, Liqi Chen, Tianfang Kang, Yiran He, Guojun Huang, Sidi Zheng, Ting Yin, Hong Pan, Lintao Cai   +10 more
wiley   +1 more source

Inhibition of DNA ejection from bacteriophage by Mg+2 counterions

, 2010
The problem of inhibiting viral DNA ejection from bacteriophages by multivalent counterions, specifically Mg$^{+2}$ counterions, is studied. Experimentally, it is known that MgSO$_4$ salt has a strong and non-monotonic effect on the amount of DNA ejected.
Baker T. S., C. V. Tran, Sell Lee, T. T. Nguyen   +3 more
core   +1 more source

The Promising Viral Threat to Bacterial Resistance: The Uncertain Patentability of Phage Therapeutics and the Necessity of Alternative Incentives [PDF]

, 2019
Bacteriophages, or “phages,” are a category of highly adept and adaptable viruses that can infect and kill bacteria. With concerns over the burgeoning antibiotic-resistance crisis looming in recent years, scientists and policymakers have expressed a ...
Todd, Kelly
core   +2 more sources

Digital Bioassays on the Slipchip Microfluidic Devices

Advanced Sensor Research, EarlyView.
This review summarizes recent advances in SlipChip‐based digital bioassays, highlighting their simple “load and slip” operation for fluid partitioning which eliminate the need for sophisticated fluidic systems. Applications include digital nucleic acid analysis, digital protein analysis and single‐cell analysis, demonstrating the platform‘s potential ...
Qingqing Luo, Ziqing Yu, Weiyuan Lyu, Yang Luo, Lei Xu, Feng Shen   +5 more
wiley   +1 more source

Localization of Electronic States in Chain Model Based on Real DNA Sequence

, 2004
We investigate the localization property of an electron in the disordered two-chain system (ladder model) with long-range correlation as a simple model for electronic property in DNA sequence.
Aizawa, Aizawa, Badi, Berlin, Bruinsma, Buldyrev, Carpena, Carpena, Crisanti, Cuniberti, Damle, de Moura, Di Felice, Grosse, Hennig, Hennig, Hiroaki Yamada, Holste, Holste, Iguchi, Iguchi, Iguchi, Iguchi, Isohata, Kats, Kurita, Ladik, Ladik, LeBard, Lewis, Ohno, Paun, Porath, Porath, Roche, Roche, Rodriguez, Shen, Starikov, Tikhonov, Tran, Troisi, Voss, Yamada, Yamada, Yamada, Yamada, Yamada, Yu   +48 more
core   +2 more sources

Molecular bases and role of viruses in the human microbiome. [PDF]

, 2014
Viruses are dependent biological entities that interact with the genetic material of most cells on the planet, including the trillions within the human microbiome.
Abeles, Shira R, Pride, David T
core   +1 more source

Parkinson’s disease and bacteriophages as its overlooked contributors

bioRxiv, 2018
Recent studies suggest that alterations in the gut phagobiota may contribute to pathophysiological processes in mammals; however, the association of bacteriophage community structure with Parkinson’s disease (PD) has not been yet characterized.
G. Tetz, Stuart M. Brown, Y. Hao, V. Tetz   +3 more
semanticscholar   +1 more source

Exploring AAV‐Mediated Gene Therapy for Inner Ear Diseases: from Preclinical Success to Clinical Potential

Advanced Science, EarlyView.
Current preclinical studies of AAV‐mediated gene therapy explore different strategies based on the characteristics of inner ear diseases. For genetic hearing loss, approaches include the replacement of a “good gene,” removal of a “bad gene,” or direct correction of mutations through base editing.
Fan Wu, Wuhui He, Yun Xiao, Qiong Wu, Qing Zhang, Tiesong Zhang, Lei Xu, Xinyi Pang   +7 more
wiley   +1 more source