Mathematical Modeling of CRISPR-CAS system effects on biofilm formation [PDF]
arXiv, 2016 Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR), linked with CRISPR associated (CAS) genes, play a profound role in the interactions between phage and their bacterial hosts. It is now well understood that CRISPR-CAS systems can confer adaptive immunity against bacteriophage infections.
arxiv
Animal Research and One Health, EarlyView.The AMP‐induced mutant Staphylococcus aureus strain nzR showed increased resistance, five gene mutations, and decreased surface anion levels. AMPs affect the NDH‐2 protein encoded by ndh gene inhibiting the growth of S. aureus. The deletion of the ndh gene promotes the development of AMPs resistance.
Lingyu Xiao +12 more
wiley +1 more source
The Promising Viral Threat to Bacterial Resistance: The Uncertain Patentability of Phage Therapeutics and the Necessity of Alternative Incentives [PDF]
, 2014 Bacteriophages, or “phages,” are a category of highly adept and adaptable viruses that can infect and kill bacteria. With concerns over the burgeoning antibiotic-resistance crisis looming in recent years, scientists and policymakers have expressed a ...
Todd, Kelly
core +2 more sources
Using ChatGPT as a tool for training nonprogrammers to generate genomic sequence analysis code
Biochemistry and Molecular Biology Education, EarlyView.Abstract Today, due to the size of many genomes and the increasingly large sizes of sequencing files, independently analyzing sequencing data is largely impossible for a biologist with little to no programming expertise. As such, biologists are typically faced with the dilemma of either having to spend a significant amount of time and effort to learn ...
Haley A. Delcher +16 more
wiley +1 more source
Brief overview on Bacteriophage therapy; Alternative to Antibiotics [PDF]
arXivThe term bacteriophage means killer or eater of bacteria. They were initially discovered by F.W. Twort and later on, Felix d'Herelle unveiled them to the world in 1910. Phage therapy has arisen as a favorable option to conventional antibiotics by reducing the multinational problem of increasing antibacterial resistance.
arxiv
Effects of Specific Antisera on the Growth of Bacterial Viruses (Bacteriophages) [PDF]
, 1945 M. Delbrück
openalex +1 more source
The contribution of extracellular RNA and its derived biomaterials in disease management
BMEMat, EarlyView.The implications of exRNA's biological function and the structural uniqueness of RNA help establish a close connection between RNA, material, and modern medicine. Abstract The RNA found in the circular system is known as extracellular RNA (exRNA). This kind of RNA has been found to play a biological role similar to that of a messenger. They can be used
Yu Wei +8 more
wiley +1 more source
A rapid and simple protocol for the isolation of bacteriophages from coastal organisms
MethodsX, 2019 This work details a protocol for recovering bacteriophages from intertidal sessile mussels and testing their lytic activity against pathogenic bacteria.
Alex Echeverría-Vega +4 more
doaj
The Protective Action of Dysentery Bacteriophage in Experimental Infections in Mice [PDF]
, 1945 Harry E. Morton, Frank B. Engley
openalex +1 more source