The CD47–SIRPα axis has emerged as a critical innate immune checkpoint that suppresses macrophage‐mediated phagocytosis through a canonical “don't eat me” signal and enables tumor immune evasion. We comprehensively summarize the structural and biological features of CD47 and the molecular mechanisms underlying CD47‐mediated regulation of phagocytosis ...
Ruimei Zhou +4 more
wiley +1 more source
Combined treatment with bacteriophages and sodium hypochlorite against <i>E. faecalis</i> biofilm in an <i>in vitro</i> root canal model with evaluation of bacterial resistance. [PDF]
Steffen K +4 more
europepmc +1 more source
DOM: Dual Optical Mapping Integrating Sequence‐Specific Barcodes and A/T Density Profiles
Dual Optical Mapping (DOM) combines sequence‐specific barcodes and an A/T profile to generate complementary genomic signatures along single DNA molecules. The integration of sparse and dense mapping information enables accurate and confident genome mapping, facilitating reliable localization of long DNA molecules in complex genomes, including the ...
Jaeyoung Bae +10 more
wiley +1 more source
Complete genome sequence of MP2445, a mycobacteriophage that can infect <i>Mycobacterium bovis</i> BCG and <i>Mycobacterium fortuitum</i>. [PDF]
Zhu X +8 more
europepmc +1 more source
Recent Advances in Photocatalyst‐Driven Protein Labeling and Proximity Mapping
Photocatalyst‐driven protein labeling and proximity mapping have rapidly advanced as powerful strategies for spatiotemporal control in complex biological environments. This review integrates recent developments across single‐electron transfer and energy transfer‐based mechanisms and highlights how catalyst design, reactive intermediates, and diffusion ...
Shinichi Sato +3 more
wiley +1 more source
Isolation of Bacteriophages with Lytic Activity from Biological Samples of Left Ventricular Assist Device Patients: An In Vitro Study. [PDF]
Sax B +10 more
europepmc +1 more source
This study systematically organizes the evolution of diagnostic antibodies from discovery platforms to design‐oriented engineering and analyzes the strengths and limitations of each approach. Meanwhile, it provides a critical, literature‐driven synthesis of current challenges, proposing integrated strategies for assay‐aware and function‐driven antibody
Qitao Song +14 more
wiley +1 more source
Genome sequence of lytic phage phi1_164023 targeting ST23 KL1-type carbapenem-resistant <i>Klebsiella pneumoniae</i>. [PDF]
Kuang H, Fang Q, Feng Y, Zong Z.
europepmc +1 more source

