Results 31 to 40 of about 1,182 (121)

Uncovering the Lipid Interface in Neurotransmission: Single Molecule Measurements of Neurotransmitters Interacting with Membranes Reveal Species Dependent Membrane Binding

open access: yesAdvanced Science, Volume 13, Issue 11, 23 February 2026.
Using single‐molecule whispering gallery mode sensors, neurotransmitter‐specific membrane binding signatures are measured that reveal intrinsically distinct interaction kinetics and orientations on a lipid membrane. Abstract Neurotransmitters (NTs) have traditionally been understood to act via aqueous‐phase receptor binding, but growing evidence ...
Thomas L. Derrien   +4 more
wiley   +1 more source

Chromophore equilibria in bacteriorhodopsin

open access: yesBiophysical Journal, 1979
An investigation of the dark equilibria between different chromophores of bacteriorhodopsin (BR) and studies of the kinetics of their interconversion and photochemical activity have led to the following conclusions. (a) A component of the 605-nm chromophore of BR decays in the millisecond range and is likely to be identical to the intermediate O of the
Fischer, U., Oesterhelt, D.
openaire   +2 more sources

Recent Advances in Vesicular Systems for Applications in Artificial Photosynthesis and Photocatalysis

open access: yesSmall Structures, Volume 7, Issue 2, February 2026.
Bioinspired vesicles are emerging as programmable nanoreactors for photocatalytic applications. This review covers the recent advances in artificial vesicles, including liposomes, polymersomes, proteinosomes, and hybrid vesicles, for compartmentalized photocatalysis, comparing their properties and assembly routes, showing how their properties affect ...
Edelman José Espinoza‐Suárez   +4 more
wiley   +1 more source

Stimuli‐Responsive Chemical Systems That Mimic Biological Dynamics

open access: yesChemistry – A European Journal, Volume 32, Issue 1, 2 January 2026.
Chemists are designing synthetic systems that mimic life's dynamic behaviors, such as motion, sensing, adaptation, and compartmentalization, by integrating reaction networks with stimuli like light, pH, and chemical fuels. This mini‐review surveys molecular machines, responsive materials, nucleic acid networks, and artificial cells, highlighting how ...
Antonio Aguanell   +3 more
wiley   +1 more source

Bi‐Functional Topospecific Nanoparticles to Promote Immune‐Tumor Cell Engagement as A New Immunotherapeutic Strategy

open access: yesAdvanced Materials, Volume 38, Issue 2, 8 January 2026.
A Janus‐engineered nanoplatform (J‐pHLIP‐PD1), featuring separate tumor‐ and immune‐targeting faces, bridges melanoma cells and cytotoxic T lymphocytes using toposelective pHLIP and anti‐PD‐1 presentation. This strategy elicits robust antitumor responses, promotes immunogenic tumor cell death, suppresses lung metastasis in vivo, and provides a modular,
Alba Ortuño‐Bernal   +9 more
wiley   +1 more source

Stabilized Ion Selectivity Corrects Activation Drift in Kalium Channelrhodopsins

open access: yesAdvanced Science, Volume 13, Issue 6, 30 January 2026.
As newly emerged optogenetic tools, potassium channelrhodopsins (KCRs) can drift from inhibition to activation during illumination as K⁺ selectivity declines. It is shown that both the absolute K⁺/Na⁺ permeability ratio and its stability over time govern this drift, identify KCR1‐C29D as a reliably inhibitory variant, and outline design principles for ...
Xiao Duan   +14 more
wiley   +1 more source

Strategies for mitigating radiation damage and improving data completeness in 3D electron diffraction of protein crystals

open access: yesActa Crystallographica Section D, Volume 82, Issue 1, Page 11-22, January 2026.
This work demonstrates that multi‐position data acquisition mitigates radiation damage in electron diffraction of three‐dimensional protein crystals and that merging data from selected crystals in distinct orientations enhances completeness. Application of the two approaches enables high‐quality structural models to be obtained from limited or ...
Alaa Shaikhqasem   +8 more
wiley   +1 more source

Entwicklung künstlicher Mitochondrien mit selbstverstärkender Protonenerzeugung für die autonome Energieversorgung und metabolische Kopplung in künstlichen Zellen

open access: yesAngewandte Chemie, Volume 137, Issue 48, November 24, 2025.
Ein ATP‐Generator, der Mitochondrien nachahmt, verbessert die Enzyminstabilität von enzymbasierten künstlichen Mitochondrien und beseitigt die Toxizität von H2O2 durch quantitative Enzym‐Co‐Kompartimentierung. Die resultierenden künstlichen Mitochondrien können einen nachhaltigen Protonengradienten für die ATP‐Synthese aufbauen.
Fangqin Fu   +7 more
wiley   +1 more source

Engineering Artificial Mitochondria with Self‐Amplifying Proton Generation for Autonomous Energy Supply and Metabolic Coupling in Artificial Cells

open access: yesAngewandte Chemie International Edition, Volume 64, Issue 48, November 24, 2025.
A mitochondria‐mimicking ATP generator improves the enzyme instability of enzyme‐based artificial mitochondria and eliminates the toxicity of H2O2 via quantitative enzyme co‐compartmentalization. The resulting artificial mitochondria can establish a sustained proton gradient for ATP synthesis.
Fangqin Fu   +7 more
wiley   +1 more source

One Dimensional Metal Oxide Semiconductor Nanotransistors

open access: yesAdvanced Materials Technologies, Volume 10, Issue 21, November 6, 2025.
This review assesses one dimensional metal oxide NW‐FETs as promising alternatives to conventional transistors. It explores how advances in architecture, material composition, and fabrication processes expand device capabilities. Emphasis is placed on novel gate configurations, different metal oxide nanowires, and post‐treatment methods, which ...
Mariana D. Cortinhal   +2 more
wiley   +1 more source

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