Results 31 to 40 of about 1,182 (121)
Using single‐molecule whispering gallery mode sensors, neurotransmitter‐specific membrane binding signatures are measured that reveal intrinsically distinct interaction kinetics and orientations on a lipid membrane. Abstract Neurotransmitters (NTs) have traditionally been understood to act via aqueous‐phase receptor binding, but growing evidence ...
Thomas L. Derrien +4 more
wiley +1 more source
Chromophore equilibria in bacteriorhodopsin
An investigation of the dark equilibria between different chromophores of bacteriorhodopsin (BR) and studies of the kinetics of their interconversion and photochemical activity have led to the following conclusions. (a) A component of the 605-nm chromophore of BR decays in the millisecond range and is likely to be identical to the intermediate O of the
Fischer, U., Oesterhelt, D.
openaire +2 more sources
Bioinspired vesicles are emerging as programmable nanoreactors for photocatalytic applications. This review covers the recent advances in artificial vesicles, including liposomes, polymersomes, proteinosomes, and hybrid vesicles, for compartmentalized photocatalysis, comparing their properties and assembly routes, showing how their properties affect ...
Edelman José Espinoza‐Suárez +4 more
wiley +1 more source
Stimuli‐Responsive Chemical Systems That Mimic Biological Dynamics
Chemists are designing synthetic systems that mimic life's dynamic behaviors, such as motion, sensing, adaptation, and compartmentalization, by integrating reaction networks with stimuli like light, pH, and chemical fuels. This mini‐review surveys molecular machines, responsive materials, nucleic acid networks, and artificial cells, highlighting how ...
Antonio Aguanell +3 more
wiley +1 more source
A Janus‐engineered nanoplatform (J‐pHLIP‐PD1), featuring separate tumor‐ and immune‐targeting faces, bridges melanoma cells and cytotoxic T lymphocytes using toposelective pHLIP and anti‐PD‐1 presentation. This strategy elicits robust antitumor responses, promotes immunogenic tumor cell death, suppresses lung metastasis in vivo, and provides a modular,
Alba Ortuño‐Bernal +9 more
wiley +1 more source
Stabilized Ion Selectivity Corrects Activation Drift in Kalium Channelrhodopsins
As newly emerged optogenetic tools, potassium channelrhodopsins (KCRs) can drift from inhibition to activation during illumination as K⁺ selectivity declines. It is shown that both the absolute K⁺/Na⁺ permeability ratio and its stability over time govern this drift, identify KCR1‐C29D as a reliably inhibitory variant, and outline design principles for ...
Xiao Duan +14 more
wiley +1 more source
This work demonstrates that multi‐position data acquisition mitigates radiation damage in electron diffraction of three‐dimensional protein crystals and that merging data from selected crystals in distinct orientations enhances completeness. Application of the two approaches enables high‐quality structural models to be obtained from limited or ...
Alaa Shaikhqasem +8 more
wiley +1 more source
Ein ATP‐Generator, der Mitochondrien nachahmt, verbessert die Enzyminstabilität von enzymbasierten künstlichen Mitochondrien und beseitigt die Toxizität von H2O2 durch quantitative Enzym‐Co‐Kompartimentierung. Die resultierenden künstlichen Mitochondrien können einen nachhaltigen Protonengradienten für die ATP‐Synthese aufbauen.
Fangqin Fu +7 more
wiley +1 more source
A mitochondria‐mimicking ATP generator improves the enzyme instability of enzyme‐based artificial mitochondria and eliminates the toxicity of H2O2 via quantitative enzyme co‐compartmentalization. The resulting artificial mitochondria can establish a sustained proton gradient for ATP synthesis.
Fangqin Fu +7 more
wiley +1 more source
One Dimensional Metal Oxide Semiconductor Nanotransistors
This review assesses one dimensional metal oxide NW‐FETs as promising alternatives to conventional transistors. It explores how advances in architecture, material composition, and fabrication processes expand device capabilities. Emphasis is placed on novel gate configurations, different metal oxide nanowires, and post‐treatment methods, which ...
Mariana D. Cortinhal +2 more
wiley +1 more source

