Results 21 to 30 of about 1,206 (141)

On the two forms of bacteriorhodopsin

open access: yesFEBS Letters, 1994
In our previous work [(1993) FEBS Lett. 313, 248‐250; (1993) Biochem. Int. 30,461‐469] M‐intermediate formation of wild‐type bacteriorhodopsin was shown to involve two components differing in time constants (τ1 = 60–70 μs and τ2 = 220–250 μs), which were suggested to reflect two independent pathways of M‐intermediate formation.
Komrakov, Andrey Yu., Kaulen, Andrey D.
openaire   +2 more sources

Let There be Light! Light as an Engine and Regulator in Synthetic Cells

open access: yesAngewandte Chemie International Edition, Volume 65, Issue 24, 8 June 2026.
Cells are out‐of‐equilibrium systems that regulate their spatiotemporal features. In biomimetic synthetic cells, light offers a unique way for energizing and regulating events in space and time. This review explores the implementation of light‐responsive tools in synthetic cells to replicate biological functions and enable new bioinspired behaviors ...
Matthew E. Allen   +5 more
wiley   +1 more source

Wave Mechanics of Ciliary Proteins: Quantum‐Enabled Sensing and Energy Transfer in the “Cellular Antenna”

open access: yesAggregate, Volume 7, Issue 6, June 2026.
This review surveys eukaryotic cilia as putative quantum‐enabled sensory and regulatory centers. It highlights their multifaceted roles in the cell, focuses on the nontrivial roles of quantum mechanics in their membrane and cytoskeletal proteins, and introduces the essential building blocks enabling quantum properties to survive in the warm, wet, and ...
Daniel L. Bilezikian   +5 more
wiley   +1 more source

Photoisomerization detected in a fully wavelength‐tunable rhodopsin mimic system

open access: yesActa Crystallographica Section D, Volume 82, Issue 6, Page 664-671, June 2026.
The mechanism of retinal photoswitching is illuminated in a designed rhodopsin mimic. Two mechanisms, a conventional cis–trans isomerization and an unprecedented `photodehydration', are observed at atomic resolution in single crystals.We describe the photoisomerization of the retinylidene protonated Schiff base in human retinol‐binding protein II ...
Nona Ehyaei   +10 more
wiley   +1 more source

GRKs and arrestins: Nomenclature and functions in GPCR‐dependent and ‐independent signalling

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 11, Page 2619-2633, June 2026.
G protein‐coupled receptor (GPCR) kinases (GRKs) and arrestins play a critical role in the regulation of GPCR signalling. Historic names of mammalian GRKs were replaced by systematic ones in the 1990s; however, both kinds of names are currently in use for mammalian arrestins.
Vsevolod V. Gurevich
wiley   +1 more source

Chromophore equilibria in bacteriorhodopsin

open access: yesBiophysical Journal, 1979
An investigation of the dark equilibria between different chromophores of bacteriorhodopsin (BR) and studies of the kinetics of their interconversion and photochemical activity have led to the following conclusions. (a) A component of the 605-nm chromophore of BR decays in the millisecond range and is likely to be identical to the intermediate O of the
Fischer, U., Oesterhelt, D.
openaire   +2 more sources

Meniscus‐Mediated Imaging of Soft Biological Membranes Using 200 kN/m Ultra‐Stiff 15 MHz MEMS AFM Probes

open access: yesJournal of Molecular Recognition, Volume 39, Issue 3, May 2026.
ABSTRACT Coronaviruses, among other membrane‐enveloped viruses, can remain infectious on surfaces in ambient air for days. Many bacteria and fungi also expose their plasma membranes to air environments. Key survival strategies in air include hydrophobic coatings to prevent water loss and waxy or silica‐based resistant cell walls.
Suyambulingam Subramanian   +3 more
wiley   +1 more source

Engineering of soluble bacteriorhodopsin

open access: yesChemical Science
Analogues of membrane protein bacteriorhodopsin are reported that are soluble and stable, bind retinal and exhibit photocycles under illumination, highlighting the power of modern protein engineering approaches.
Andrey Nikolaev   +14 more
openaire   +2 more sources

Electrons and X‐rays for diffraction and imaging

open access: yesActa Crystallographica Section D, Volume 82, Issue 5, Page 446-456, May 2026.
The use of X‐rays and electrons for diffraction and imaging of soft biological samples is compared.A comparison is provided between the use of electrons and X‐rays for collecting diffraction data from small protein crystals and imaging data from cells and tissues.
Colin Nave   +2 more
wiley   +1 more source

Damage‐limited resolution for X‐ray and electron microscopy of organic specimens

open access: yesActa Crystallographica Section D, Volume 82, Issue 5, Page 471-483, May 2026.
Analytical expressions for the damage‐limited resolution are developed and applied to X‐ray and electron imaging of beam‐sensitive specimens. The findings will guide future microscopy and instrument design.Analytical expressions for the damage‐limited resolution (DLR) are developed and applied to X‐ray and electron imaging of beam‐sensitive specimens ...
Ray F. Egerton, Colin Nave
wiley   +1 more source

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