Results 21 to 30 of about 1,206 (141)
On the two forms of bacteriorhodopsin
In our previous work [(1993) FEBS Lett. 313, 248‐250; (1993) Biochem. Int. 30,461‐469] M‐intermediate formation of wild‐type bacteriorhodopsin was shown to involve two components differing in time constants (τ1 = 60–70 μs and τ2 = 220–250 μs), which were suggested to reflect two independent pathways of M‐intermediate formation.
Komrakov, Andrey Yu., Kaulen, Andrey D.
openaire +2 more sources
Let There be Light! Light as an Engine and Regulator in Synthetic Cells
Cells are out‐of‐equilibrium systems that regulate their spatiotemporal features. In biomimetic synthetic cells, light offers a unique way for energizing and regulating events in space and time. This review explores the implementation of light‐responsive tools in synthetic cells to replicate biological functions and enable new bioinspired behaviors ...
Matthew E. Allen +5 more
wiley +1 more source
This review surveys eukaryotic cilia as putative quantum‐enabled sensory and regulatory centers. It highlights their multifaceted roles in the cell, focuses on the nontrivial roles of quantum mechanics in their membrane and cytoskeletal proteins, and introduces the essential building blocks enabling quantum properties to survive in the warm, wet, and ...
Daniel L. Bilezikian +5 more
wiley +1 more source
Photoisomerization detected in a fully wavelength‐tunable rhodopsin mimic system
The mechanism of retinal photoswitching is illuminated in a designed rhodopsin mimic. Two mechanisms, a conventional cis–trans isomerization and an unprecedented `photodehydration', are observed at atomic resolution in single crystals.We describe the photoisomerization of the retinylidene protonated Schiff base in human retinol‐binding protein II ...
Nona Ehyaei +10 more
wiley +1 more source
GRKs and arrestins: Nomenclature and functions in GPCR‐dependent and ‐independent signalling
G protein‐coupled receptor (GPCR) kinases (GRKs) and arrestins play a critical role in the regulation of GPCR signalling. Historic names of mammalian GRKs were replaced by systematic ones in the 1990s; however, both kinds of names are currently in use for mammalian arrestins.
Vsevolod V. Gurevich
wiley +1 more source
Chromophore equilibria in bacteriorhodopsin
An investigation of the dark equilibria between different chromophores of bacteriorhodopsin (BR) and studies of the kinetics of their interconversion and photochemical activity have led to the following conclusions. (a) A component of the 605-nm chromophore of BR decays in the millisecond range and is likely to be identical to the intermediate O of the
Fischer, U., Oesterhelt, D.
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ABSTRACT Coronaviruses, among other membrane‐enveloped viruses, can remain infectious on surfaces in ambient air for days. Many bacteria and fungi also expose their plasma membranes to air environments. Key survival strategies in air include hydrophobic coatings to prevent water loss and waxy or silica‐based resistant cell walls.
Suyambulingam Subramanian +3 more
wiley +1 more source
Engineering of soluble bacteriorhodopsin
Analogues of membrane protein bacteriorhodopsin are reported that are soluble and stable, bind retinal and exhibit photocycles under illumination, highlighting the power of modern protein engineering approaches.
Andrey Nikolaev +14 more
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Electrons and X‐rays for diffraction and imaging
The use of X‐rays and electrons for diffraction and imaging of soft biological samples is compared.A comparison is provided between the use of electrons and X‐rays for collecting diffraction data from small protein crystals and imaging data from cells and tissues.
Colin Nave +2 more
wiley +1 more source
Damage‐limited resolution for X‐ray and electron microscopy of organic specimens
Analytical expressions for the damage‐limited resolution are developed and applied to X‐ray and electron imaging of beam‐sensitive specimens. The findings will guide future microscopy and instrument design.Analytical expressions for the damage‐limited resolution (DLR) are developed and applied to X‐ray and electron imaging of beam‐sensitive specimens ...
Ray F. Egerton, Colin Nave
wiley +1 more source

