Results 81 to 90 of about 149,851 (301)

Extraction and Evaluation of Outer Membrane Vesicles from Two Important Gut Microbiota Members, Bacteroides fragilis and Bacteroides thetaiotaomicron

Cell Journal, 2020
Objective: The gastrointestinal tract (GI) is colonized by a complex microbial community of gut microbiota. Bacteroides spp. have significant roles in gut microbiota and they host interactions by various mechanisms, including outer membrane vesicle ...
Sara Ahmadi Badi, Arfa Moshiri, Fatemeh Ettehad Marvasti, Mojtaba Mojtahedzadeh, Vida Kazemi, Seyed Davar Siadat   +5 more
doaj   +1 more source

Hadza Prevotella require diet-derived microbiota-accessible carbohydrates to persist in mice

Cell Reports, 2023
Summary: Industrialization has transformed the gut microbiota, reducing the prevalence of Prevotella relative to Bacteroides. Here, we isolate Bacteroides and Prevotella strains from the microbiota of Hadza hunter-gatherers in Tanzania, a population with
Rebecca H. Gellman, Matthew R. Olm, Nicolas Terrapon, Fatima Enam, Steven K. Higginbottom, Justin L. Sonnenburg, Erica D. Sonnenburg   +6 more
doaj   +1 more source

Empyema necessitans and a persistent air leak associated with rupture of an anaerobic lung abscess due to bacteroides [PDF]

, 2017
No abstract ...
Blyth, Kevin G., Sharma, Varun
core   +1 more source

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

Advanced Science, EarlyView.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu, Hongjie Dai, Xiaocui Zhong, Qibin Li, Hui Yuan, Yang Yang, Daiyong Huang, Lei Zhang, Rui Ran, Tian He, Yuanzhi Huang, Silas Villas‐Boas, Sergey Tumanov, Richard D. Cannon, Boris Novakovic, Richard Saffery, Yuhao Zhang, Xiaojing Dong, Ting‐Li Han   +18 more
wiley   +1 more source

Optimal Algorithm for Gut Microbiota Differentiation: A Pilot Study of Adolescents with Different Body Weights

Frontiers in Bioscience-Scholar
Background: The enterotype concept allows the differentiation of gut microbiota in relation to individual characteristics and is determined by the genetics and external stressors of the host.
Natalia Belkova, Elizaveta Klimenko, Natalya Semenova, Anna Pogodina, Lyubov Rychkova, Olga Bugun, Lubov Kolesnikova, Marina Darenskaya   +7 more
doaj   +1 more source

The impact of sequence database choice on metaproteomic results in gut microbiota studies [PDF]

, 2016
Background: Elucidating the role of gut microbiota in physiological and pathological processes has recently emerged as a key research aim in life sciences.
Addis, Maria Filippa, Deligios, Massimo, Fraumene, Cristina, Manghina, Valeria, Martens, Lennart, Muth, Thilo, Pagnozzi, Daniela, Palomba, Antonio, Rapp, Erdmann, Tanca, Alessandro, Uzzau, Sergio   +10 more
core   +4 more sources

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

Advanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey, Sudhir Kumar Rai, Li Ma, Lauren Higa, Vedbar Khadka, Hua Yang, Youping Deng   +6 more
wiley   +1 more source

Fluorogenic Coupled Assays Reveal Catalytic Properties, Inhibition Constants and Cellular Location of Mucin‐Active Carbohydrate Sulfatases

Angewandte Chemie, EarlyView.
We report plate‐based coupled assays to rapidly and quantitatively determine the activity and selectivity of mucin‐active carbohydrate sulfatases. This fluorogenic assay further enables inhibitor identification and allows determination of (sub‐)cellular location. ABSTRACT Sulfated glycans play a central role in human health and influence cell signaling,
Charles W. E. Tomlinson, Madouc D. Bergers, David N. Bolam, Ana S. Luis, Alan Cartmell, Zachary Armstrong   +5 more
wiley   +2 more sources

Bacteroides ovatus ATCC 8483 monotherapy is superior to traditional fecal transplant and multi-strain bacteriotherapy in a murine colitis model

Gut Microbes, 2019
Background and aims Bacteriotherapy aimed at addressing dysbiosis may be therapeutic for Inflammatory Bowel Diseases (IBDs). We sought to determine if defined Bacteroides-based bacteriotherapy could be an effective and consistent alternative to fecal ...
Faith D. Ihekweazu, Tatiana Y. Fofanova, Karen Queliza, Dorottya Nagy-Szakal, Christopher J. Stewart, Melinda A. Engevik, Kristina G. Hulten, Nina Tatevian, David Y. Graham, James Versalovic, Joseph F. Petrosino, Richard Kellermayer   +11 more
doaj   +1 more source

Icariin Enhances the Enzymatic Activity of N‐acetylgalactosaminidase to Augment Akkermansia Abundance in Gut Microbiota for Improved PD‐1 Blockade Efficacy in Tumor Suppression

Advanced Science, EarlyView.
Icariin promoted the growth of Akk by enhancing the activity of N‐acetylgalactosaminidase (Amuc_0920), which enhanced mucin utilization and provided a favorable nutrient environment for bacterial growth. This icariin‐mediated enrichment of Akk further reshaped the tumor microenvironment and promoted CD8+ T cell infiltration, ultimately synergizing with
Shuangying Qiao, Liu Yang, Haibang Hao, Qiuxia Ding, Feng Ding, Zheng Chen, Jinfang Zhang, Yun He, Meng Li, Jun Xu, Chao Wang, Aiping Lu, Fangfei Li   +12 more
wiley   +1 more source