Results 41 to 50 of about 17,598 (208)

Discovery of two novel Flavobacterium species with potential for complex polysaccharide degradation

Scientific Reports
Polysaccharides are recognized for their extensive biological functions, holding significant promise for applications in both medicine and food industries.
Xu-Dong Lian, Yong Guan, Yue Jiang, Dong-Heui Kwak, Mi-Kyung Lee, Zhun Li   +5 more
doaj   +1 more source

Microalgae Hybrid Biosystem for Enhanced Oral Delivery of Rifaximin in Hepatic Encephalopathy Treatment

Advanced Science, EarlyView.
The microalgae‐nanoparticle hybrid system with antibacterial activity can improve the oral delivery and therapeutic efficiency for hepatic encephalopathy treatment. Oral administration of the system can reduced systemic ammonia levels, enhanced intestinal barrier function, attenuated systemic and neuroinflammation, ameliorated cognitive impairments ...
Kaiyue Wang, Xueting Huang, Lingxiao Yang, Jin Liu, Lei Lei, Shaomin Zou, Kai Wang, Min Zhou, Zhe Tang   +8 more
wiley   +1 more source

LolA and LolB are conserved in Bacteroidota and are crucial for gliding motility and Type IX secretion

Communications Biology
Lipoproteins are key outer membrane (OM) components in Gram-negative bacteria, essential for functions like membrane biogenesis and virulence. Bacteroidota, a diverse and widespread phylum, produce numerous OM lipoproteins that play vital roles in ...
Tom De Smet, Elisabeth Baland, Fabio Giovannercole, Julien Mignon, Laura Lizen, Rémy Dugauquier, Frédéric Lauber, Marc Dieu, Gipsi Lima-Mendez, Catherine Michaux, Damien Devos, Francesco Renzi   +11 more
doaj   +1 more source

Analysis of the tripartite interactions between two bacterial symbionts, a novel Solitalea-like bacterium (Bacteroidota) and Cardinium, and the stored product mite Tyrophagus putrescentiae based on gene expression data

Microbiology Spectrum
The intracellular parasite Cardinium influences the bacterial microbiome composition of arthropod hosts; however, the mechanisms involved remain poorly understood.
Jan Hubert, Qing Xiong, Eliza Glowska-Patyniak, Elizabeth V. Furtak, Pavel B. Klimov   +4 more
doaj   +1 more source

Structure of a distinct β-barrel assembly machinery complex in the Bacteroidota

Nature Microbiology
Abstract The Gram-negative β-barrel assembly machinery (BAM) complex catalyses the folding and membrane insertion of newly synthesized β-barrel outer membrane proteins. The BAM is structurally conserved, but most studies have focused on Gammaproteobacteria. Here, using single-particle cryogenic electron microscopy,
Augustinas Silale, Mariusz Madej, Katarzyna Mikruta, Andrew M. Frey, Adam J. Hart, Arnaud Baslé, Carsten Scavenius, Jan J. Enghild, Matthias Trost, Robert P. Hirt, Bert van den Berg   +10 more
openaire   +6 more sources

Disrupting Helicobacter pylori Iron Homeostasis With Bismuth Nanodrug‐Mediated Nutritional Trap for Targeted Gastric Infection Therapy

Advanced Science, EarlyView.
A “nutritional trap” strategy centered on disrupting bacterial iron homeostasis is proposed. The synthesized Bi‐TP@FU (TBF) can target Helicobacter pylori, interfere with the bacterial iron uptake and utilization processes to disrupt its iron homeostasis, induce bacterial death, and meanwhile preserve the balance of the intestinal flora.
Tianye Fang, Jinzhe Tong, Feng Feng, Cong Liu, Chang Shu, Jiaying Zhu, Shibo Zhang, Shuyue Deng, Wanchao Zuo, Yuhan Song, Jun Yang, Yanmin Ju, Yingying Xing, Jianjun Dai   +13 more
wiley   +1 more source

Oral Delivery Systems for Food‐Derived Bioactive Peptides: Enhancing Stability, Bioavailability, and Health Benefits

Advanced Science, EarlyView.
Advanced delivery systems—including nanoparticles, nanoemulsions, liposomes, and hydrogels—protect food‐derived bioactive peptides from gastrointestinal degradation and bitterness. These systems enable pH‐responsive release, enhance intestinal absorption, and improve therapeutic efficacy against oxidative stress, metabolic disorders, cancer, and ...
Yu Xu, Fan Li, Runan Zhao, Tao Shu, Weihong Min, Bei‐Wei Zhu   +5 more
wiley   +1 more source

Metagenome-derived SusD-homologs affiliated with Bacteroidota bind to synthetic polymers

Applied and Environmental Microbiology
ABSTRACT S tarch u tilization s ystem (Sus)D-homologs are well known for their carbohydrate-binding capabilities and are part of the sus operon in microorganisms affiliated with the phylum Bacteroidota ...
Myllena Pereira Silverio, Tabea Neumann, Kirsten Schaubruch, Ralf Heermann, Pablo Pérez-García, Jennifer Chow, Wolfgang R. Streit   +6 more
openaire   +2 more sources

Innovative Test Strip‐Based Colorimetric Sensors Integrated With Affinity Chromatography: Acetylcholinesterase Inhibitor Screening Breakthrough in Lycium Barbarum Leaves

Advanced Science, EarlyView.
Schematic diagrams illustrating the breakthrough in the screening of AChE inhibitors from LBL, and the research process of the pharmacodynamics of the NCP are presented. ABSTRACT Current Alzheimer's drugs exhibit limited effectiveness, highlighting the necessity for multi‐target treatments.
Yuping Sa, Hui Yuan, Jingui Ma, Zhigang Yang, Mei Wang, Weibiao Wang, Lingling Yang, Fen Ma, Weiman Zhang, Gidion Wilson Mening'oo, Guoning Chen, Xueqin Ma   +11 more
wiley   +1 more source

Arylsulfamates inhibit colonic Bacteroidota growth through a sulfatase-independent mechanism

Proceedings of the National Academy of Sciences
Excessive degradation of the colonic mucin layer by Bacteroides within the human gut microbiota drives inflammatory bowel disease (IBD) in mice. Bacterial carbohydrate sulfatases are key enzymes in gut colonization, and they are elevated in human IBD and correlate with disease severity ...
Conor J. Crawford, Charles W. E. Tomlinson, Christian Gunawan, Zongjia Chen, Dominic P. Byrne, Cosette Darby, Martina L. G. Conti, Tony Larson, Ana S. Luis, Stefano Elli, Edwin A. Yates, David N. Bolam, Sjoerd van der Post, Spencer J. Williams, Alan Cartmell   +14 more
openaire   +4 more sources