The baculovirus expression vector system (BEVS) platform has become an established manufacturing platform for the production of viral vaccines and gene therapy vectors.
R. Felberbaum
semanticscholar +1 more source
Helicoverpa armigera nucleopolyhedrovirus occlusion-derived virus-associated protein, HA100, affects oral infectivity in vivo but not virus replication in vitro [PDF]
ORF100 (ha100) of Helicoverpa armigera nucleopolyhedrovirus (HearNPV) has been reported as one of the unique genes of group II alphabaculoviruses encoding a protein located in the occlusion-derived virus (ODV) envelope and nucleocapsid.
Deng, F. +7 more
core +3 more sources
Protease‐mediated maturation of M‐PMV reverse transcriptase into a functional heterodimer
Abstract Reverse transcriptase (RT) of retroviruses orchestrates viral replication, yet its structural diversity remains poorly understood. Well‐studied RTs, such as those from HIV‐1, murine leukemia virus, and avian myeloblastosis virus, were characterized decades ago, but less prominent retroviruses have escaped detailed analysis.
Marina Kapisheva +6 more
wiley +1 more source
A pathway of signals regulating effector and initiator caspases in the developing Drosophila eye [PDF]
Regulated cell death and survival play important roles in neural development. Extracellular signals are presumed to regulate seven apparent caspases to determine the final structure of the nervous system.
Baker, Nicholas E. +6 more
core
A new baculovirus isolate that does not cause the liquefaction of the integument in Spodoptera frugiperda dead larvae. [PDF]
The large-scale production of Baculovirus to control fall armyworm, Spodoptera frugiperda, presents many limitations. The most important limiting factor is that the baculovirus, which infects fall armyworm, causes liquefaction of the integument ...
GUIMARÃES, M. R. F. +5 more
core +1 more source
Efficient and rapid isolation of native AMPA receptor complexes for cryo‐EM
Abstract Isolating native ion channels for structural characterization is routinely achieved by extraction from membrane fractions of tissue with prolonged mild detergent treatment. AMPA receptors (AMPARs), glutamatergic receptors that mediate fast excitatory transmission and synaptic plasticity, are coassembled with diverse auxiliary subunits and ...
Jumi Park, Eric Gouaux
wiley +1 more source
BWCFF, a severe disease with neurological symptoms, is caused by mutations in the cytoskeletal actin genes. Patient‐derived fibroblasts carrying the R196H β‐actin mutation were compared to wild type cells. The mutant cells displayed slower proliferation and migration and a lower F‐actin content, which correlated with reduced cell stiffness ...
Éva Gráczer +12 more
wiley +1 more source
Baculovirus Late Expression Factors
<i>Autographa californica</i> nuclear polyhedrosis virus, or AcMNPV, is the type member of the baculoviruses, a family of double-stranded DNA viruses with large circular genomes. The successive and concomitant expression of an assortment of early, late and very late genes is instrumental for successful baculovirus infection, and requires a ...
openaire +2 more sources
A step further in our commitment to support early career researchers (ECRs)
As a not‐for‐profit open access journal, FEBS Open Bio is proud to support the scientific community not only through the publication of open access articles available to all but also through the charitable activities of FEBS. In this editorial, we look back at some of the highlights of the past year and look forward to the new initiatives planned for ...
Sara Fuentes, Miguel A. De la Rosa
wiley +1 more source
Vesivirus 2117 capsids more closely resemble sapovirus and lagovirus particles than other known vesivirus structures [PDF]
Vesivirus 2117 is an adventitious agent that in 2009, was identified as a contaminant of CHO cells propagated in bioreactors at a pharmaceutical manufacturing plant belonging to Genzyme.
Bhella, David +8 more
core +1 more source

