Results 131 to 140 of about 93,476 (270)
SIC1 is ubiquitinated in vitro by a pathway that requires CDC4, CDC34, and cyclin/CDK activities [PDF]
, 1997 Traversal from G1 to S-phase in cycling cells of budding yeast is dependent on the destruction of the S-phase cyclin/CDK inhibitor SIC1. Genetic data suggest that SIC1 proteolysis is mediated by the ubiquitin pathway and requires the action of CDC34 ...
Deshaies, Raymond J. +2 more
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The development and potential of the biological insecticide granulovirus on codling moth [PDF]
, 2006 Cydia pomonella granulovirus is being developed for the UK market and offers opportunities for orchard growers to develop reduced pesticide residue programmes when targeting codling moth ...
Horgan, A R
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High-levelexpression of functional recombinant human coagulation factor VII in insect cells [PDF]
: Recombinant coagulation factor VII (FVII) is used as a potential therapeutic intervention in hemophilia patients who produce antibodies against the coagulation factors.
AD Shapiro +30 more
core +1 more source
Cell cycle regulation of a Xenopus Wee1-like kinase [PDF]
, 1995 Using a polymerase chain reaction-based strategy, we have isolated a gene encoding a Wee1-like kinase from Xenopus eggs. The recombinant Xenopus Wee1 protein efficiently phosphorylates Cdc2 exclusively on Tyr- 15 in a cyclin-dependent manner.
Coleman, Thomas R. +2 more
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Subunit interactions within the Saccharomyces cerevisiae DNA polymerase ε (pol ε) complex - Demonstration of a dimeric pol ε [PDF]
, 2000 Saccharomyces cerevisiae DNA polymerase epsilon (pol ε) is essential for chromosomal replication. A major form of pol ε purified from yeast consists of at least four subunits: Pol2p, Dpb2p, Dpb3p, and Dpb4p.
Campbell, Judith L. +3 more
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Frontiers in MedicineIntroductionRecombinant adeno-associated virus (rAAV) vectors provide a safe and efficient means for in vivo gene delivery, although its large-scale production remains challenging. Featuring high manufacturing speed, flexible product design, and inherent
Ningguang Luo +6 more
doaj +1 more source
A viral expression factor behaves as a prion
Nature Communications, 2019 Prion-forming proteins have been found in animals, plants, fungi, and bacteria. Here, Nan et al. report that a baculovirus-encoded protein behaves as prion in a yeast system and forms aggregates at high multiplicity of infection in insect cells that ...
Hao Nan +3 more
doaj +1 more source
PLoS ONE, 2023 Due to its outstanding suitability to produce complex biopharmaceutical products including virus-like particles and subunit vaccines, the baculovirus/insect cell expression system has developed into a highly popular production platform in the ...
Christina Sophie Hausjell +4 more
doaj
A reporter for amyloid precursor protein γ-secretase activity in Drosophila [PDF]
, 2003 A key event in the pathogenesis of Alzheimer's disease (AD) is the deposition of senile plaques consisting largely of a peptide known as β-amyloid (Aβ) that is derived from the amyloid precursor protein (APP).
Fernandes, Jolene +4 more
core +1 more source