Results 111 to 120 of about 68,162 (268)

Media‐dependent performance of rabies virus‐like particle production under low oxygen tension in baculovirus‐infected Sf9 cells

open access: yesJournal of Chemical Technology &Biotechnology, Volume 101, Issue 6, Page 1273-1282, June 2026.
Abstract BACKGROUND Rabies continues to pose a major public health threat, causing approximately 59 000 deaths each year, especially in regions with limited resources where high costs restrict vaccine access. Safer and scalable vaccine platforms, such as virus‐like particles, are promising alternatives, but their production is highly sensitive to ...
Júlia Públio Rabello   +8 more
wiley   +1 more source

The MultiBac Baculovirus/Insect Cell Expression Vector System for Producing Complex Protein Biologics

open access: yesAdvances in Experimental Medicine and Biology, 2015
Multiprotein complexes regulate most if not all cellular functions. Elucidating the structure and function of these complex cellular machines is essential for understanding biology.
Duygu Sari   +7 more
semanticscholar   +1 more source

Applying Distinct CDMS Strategies to Observe Nonclassical Virus Capsid Assembly

open access: yesJournal of Mass Spectrometry, Volume 61, Issue 6, June 2026.
ABSTRACT In conventional native mass spectrometry (MS), one faces severe limitations when challenged with heterogeneous, high‐mass samples, commonly failing to resolve clear peak distributions, and thus mass determination. Charge detection MS (CDMS) has emerged as a premier method to analyze these samples by determining mass‐to‐charge ratio (m/z) and ...
Lars Thiede   +14 more
wiley   +1 more source

Ultra Deep Sequencing of a Baculovirus Population Reveals Widespread Genomic Variations

open access: yesViruses, 2015
Viruses rely on widespread genetic variation and large population size for adaptation. Large DNA virus populations are thought to harbor little variation though natural populations may be polymorphic.
A. Chateigner   +5 more
semanticscholar   +1 more source

Development of a replication-defective baculovirus platform

open access: yes, 2022
Baculovirus expression vector systems are used for the production of an increasing number of licensed commercial subunit vaccines. Though baculoviruses are incapable of replicating outside a narrow host range of lepidopteran insects, a replication ...
Ackerman, Scott Ryan
core  

Biological Pesticides as Viable Alternative to Synthetic Pesticides for Sustainable Agriculture and Nutrition: A Systematic Review

open access: yesJournal of Sustainable Agriculture and Environment, Volume 5, Issue 2, June 2026.
ABSTRACT The overuse of synthetic pesticides in agriculture has raised significant environmental and health concerns. Biopesticides have emerged as viable, environmentally compatible alternatives. However, recent comprehensive reviews integrating all biopesticide categories and emphasizing their contribution to synthetic‐pesticide‐free and health‐safe ...
Molalign Assefa   +5 more
wiley   +1 more source

Baculovirus vector-mediated transfer of sodium iodide symporter and plasminogen kringle 5 genes for tumor radioiodide therapy.

open access: yesPLoS ONE, 2014
BackgroundBoth tumor cells and their supporting endothelial cells should be considered for targeted cell killing when designing cancer treatments.
Min Zhang   +5 more
doaj   +1 more source

The evolving role of structural biology in pharma: integration of X‐ray crystallography, cryo‐electron microscopy and beyond

open access: yesActa Crystallographica Section D, Volume 82, Issue 6, Page 587-602, June 2026.
This review describes how an integrated structural biology platform at Merck Sharp & Dohme LLC, Rahway, New Jersey, USA, combining X‐ray crystallography, cryo‐EM, MicroED and cryo‐ET, enables seamless three‐dimensional insights from molecular to cellular length scales.
Jill E. Chrencik   +44 more
wiley   +1 more source

Applying Baculovirus Surface Display Technology for Influenza Cytokine Profiling, Serological Detection and Antiviral Screening

open access: yesMicrobial Biotechnology, Volume 19, Issue 6, June 2026.
By displaying the hemagglutinin (HA) or neuraminidase (NA) proteins of influenza viruses on the surface of baculoviruses and infected insect cells, a safe and flexible pseudovirus system capable of performing cytokine analysis, serological detection and antiviral drug screening is established.
Li‐Yun Cheng   +7 more
wiley   +1 more source

Development of a baculovirus vector carrying a small hairpin RNA for suppression of sf-caspase-1 expression and improvement of recombinant protein production

open access: yesBMC Biotechnology, 2018
Background The Baculovirus expression vector system (BEVS) is a transient expression platform for recombinant protein production in insect cells. Baculovirus infection of insect cells will shutoff host translation and induce apoptosis and lead to the ...
Xiaoyue Zhang   +4 more
doaj   +1 more source

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