Results 101 to 110 of about 93,476 (270)

Low multiplicity of infection in vivo results in purifying selection against baculovirus deletion mutants [PDF]

open access: yes
The in vivo fate of Autographa californica multiple nucleopolyhedrovirus deletion mutants originating from serial passage in cell culture was investigated by passaging a population enriched in these mutants in insect larvae.
Erro, E.   +4 more
core   +2 more sources

Characterization of a Baculovirus Alkaline Nuclease [PDF]

open access: yesJournal of Virology, 2000
ABSTRACT All baculovirus genomes sequenced to date encode a homolog of an alkaline nuclease that has been characterized in the Herpesviridae . In this report we describe the characterization of the alkaline nuclease (AN) homolog of the Autographa californica multinucleocapsid ...
L, Li, G F, Rohrmann
openaire   +2 more sources

Design, Synthesis, and Evaluation of Coumarin‐Rasagiline Hybrids as Multifunctional Neuroprotective Agents

open access: yesChemMedChem, Volume 21, Issue 10, 27 May 2026.
Novel coumarin‐rasagiline hybrid molecules were designed and synthesized as multifunctional agents targeting key pathological mechanisms of neurodegenerative diseases. These compounds exhibited hMAO‐B inhibitory activity, antioxidant and neuroprotective effects, supported by ADMET profiling and molecular modeling studies. The design of hybrid molecules
Aitor Carneiro   +8 more
wiley   +1 more source

Identification of a novel motif in DNA ligases exemplified by DNA ligase IV [PDF]

open access: yes, 2006
DNA ligase IV is an essential protein that functions in DNA non-homologous end-joining, the major mechanism that rejoins DNA double-strand breaks in mammalian cells. LIG4 syndrome represents a human disorder caused by mutations in DNA ligase IV that lead
Doherty, Aidan J   +5 more
core   +1 more source

A novel baculovirus-derived promoter with high activity in the baculovirus expression system

open access: yesPeerJ, 2016
The baculovirus expression vector system (BEVS) has been widely used to produce a large number of recombinant proteins, and is becoming one of the most powerful, robust, and cost-effective systems for the production of eukaryotic proteins.
Martínez-Solís, M.   +4 more
openaire   +5 more sources

Cell Cycle‐Specific Regulation of Centrosome Clustering Dynamics in Cancer Cells by the Multifunctional Kinesin HSET

open access: yesAdvanced Science, Volume 13, Issue 26, 8 May 2026.
CDK5RAP2 associates with the kinesin HSET and forms co‐condensates. HSET motors drive the directional transport of CDK5RAP2 condensates toward microtubule minus ends. During mitosis, HSET self‐assembly further stabilizes clustered centrosomes, thereby enabling pseudo‐bipolar spindle formation in cancer cells with supernumerary centrosomes. Upon mitotic
Po‐Pang Chen   +11 more
wiley   +1 more source

Genome analysis of a Glossina pallidipes salivary gland hypertrophy virus reveals a novel, large, double-stranded circular DNA virus [PDF]

open access: yes, 2008
Several species of tsetse flies can be infected by the Glossina pallidipes salivary gland hypertrophy virus (GpSGHV). Infection causes salivary gland hypertrophy and also significantly reduces the fecundity of the infected flies. To better understand the
Abd-Alla, A.M.M.   +7 more
core   +3 more sources

Engineering the transposition-based baculovirus expression vector system for higher efficiency protein production from insect cells

open access: yesJournal of Biotechnology, 2016
One of the most common methods for producing recombinant baculovirus for insect cell protein production involves a transposition mediated system invented over 2 decades ago.
Jennifer L. Mehalko, D. Esposito
semanticscholar   +1 more source

The Structure of the Chemotype Determining Locus in Cannabis sativa

open access: yesPlant Direct, Volume 10, Issue 5, May 2026.
ABSTRACT The chemical phenotype (chemotype) of Cannabis sativa is defined by the ratio of cannabidiolic acid (CBDA) to Δ9‐tetrahydrocannabinolic acid (THCA). Although the Mendelian segregation of these traits suggests a single‐locus biallelic system, recent sequencing and phylogenetic evidence indicate they are encoded by two distinct, tightly linked ...
Keith Allen   +2 more
wiley   +1 more source

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