Results 101 to 110 of about 52,750 (225)

An ALKBH3 Inhibitor HUHS199 Suppresses Proliferation of Glioblastoma Cells by Targeting 1‐Methyladenosine on GADD45A mRNA

Chemical Biology &Drug Design, Volume 108, Issue 3, September 2026.
HUHS199, a novel inhibitor of ALKBH3, suppresses glioblastoma cell proliferation, induces G1 cell cycle arrest, and increases RNA m1A levels, with concomitant changes in GADD45A mRNA methylation status, highlighting the pathological relevance of ALKBH3‐mediated RNA demethylation in glioblastoma.
Manami Yamada, Hiroaki Hase, Honoka Kitamura, Toshiya Morie, Shuntaro Aoi, Yuko Ueda, Kaori Kitae, Tatsuhiko Furukawa, Nayuta Higa, Ryosuke Hanaya, Kazutake Tsujikawa   +10 more
wiley   +1 more source

Sustained baculovirus-mediated expression in myogenic cells

, 2014
Background Baculovirus has emerged as a promising gene delivery vector due to its low cytotoxicity and nonreplication nature in mammalian cells. However, baculovirus-mediated expression is transient and generally lasts less than 14 days, which could ...
Shen, H.C., Huang, S.F., Chen, G.Y., Yeh, C.N., Hu, Y.C., Chiu, Y.C., Chen, C.Y.   +6 more
core   +2 more sources

Fusion to green fluorescent protein improves expression levels of Theileria parva sporozoite surface antigen p67 in insect cells [PDF]

, 2002
East Coast fever (ECF) is a fatal disease of cattle caused by the protozoan parasite Theileria parva. The development of a subunit vaccine, based on the sporozoite-specific surface antigen p67, has been hampered by difficulties in achieving high-level ...
Kaba, S.A., Nene, V., Musoke, A.J., Vlak, J.M., Oers, M.M., van   +4 more
core  

Biology of Baculovirus and Use of Baculovirus in Pest Control

, 2012
The University of Nevada, Reno Libraries will promptly respond to removal requests related to content that violates intellectual property laws, data protections, or has been uploaded without creator consent.
Seneviratne, Maryanne N.
core   +1 more source

Evaluation of recombinant baculovirus clearance during rAAV production in Sf9 cells using a newly developed fluorescent-TCID50 assay

Frontiers in Medicine
IntroductionRecombinant adeno-associated virus (rAAV) vectors provide a safe and efficient means for in vivo gene delivery, although its large-scale production remains challenging. Featuring high manufacturing speed, flexible product design, and inherent
Ningguang Luo, Xiangqun Chen, Jinzhong Li, Derrick Huynh, Ying Li, Li Ou, Shengjiang Liu   +6 more
doaj   +1 more source

A viral expression factor behaves as a prion

Nature Communications, 2019
Prion-forming proteins have been found in animals, plants, fungi, and bacteria. Here, Nan et al. report that a baculovirus-encoded protein behaves as prion in a yeast system and forms aggregates at high multiplicity of infection in insect cells that ...
Hao Nan, Hongying Chen, Mick F. Tuite, Xiaodong Xu   +3 more
doaj   +1 more source

Genomic support for speciation and specificity of baculoviruses [PDF]

, 2010
Keywords: baculovirus, insects, speciation, genomics, phylogeny, host specificity The Baculoviridae comprise a large family of double-stranded DNA viruses infecting arthropods.
Jakubowska, A.K.
core  

Expression of recombinant proteins in plants by using baculovirus vectors

, 2011
Baculovirus has been widely used for the production of numerous recombinant proteins in insect cells. Baculovirus vectors have several advantages, including proper post-translational modification, biosafety, and multiple large gene expression ability ...
Young Kug Choo, Y K Kim, Z Lu, Y S Han, Da-Young Park, Young Kwan Kim, Zhe Lu, Yeon Soo Han, Y K Choo, E Y Oh, D Y Park, Eun-Yi Oh, Kisung Ko, Jeong Mee Park, K Ko   +14 more
core   +1 more source

LEF-6 phosphorylation regulates the binding and trafficking of baculovirus late gene transcripts

Journal of Virology
The Autographa californica multiple nucleopolyhedrovirus (AcMNPV) LEF-6 has been shown to accelerate the infection cycle of AcMNPV, but its specific function is yet to be defined.
Xiaoyue Zhang, Zhihui Zhang, Ziqian Cao, Jianchao Li, Shengqiang Jiang, Hongying Chen   +5 more
doaj   +1 more source

Baculovirus dual promoter expression vector

, 1990
This invention relates to specifically designing and genetically engineering recombinant baculovirus for producing, in a compatible insect system, a desired protein, virus, protein hybrid, or virus hybrid. In particular aspects, this invention relates to
Oker-Blom, Christian E. G., Summers, Max D.   +1 more
core   +1 more source