Results 41 to 50 of about 232,449 (132)

Novel Germline RUNX1 Mutation Associated with Familial Thrombocytopenia as well as B-Acute Lymphoblastic Leukemia: A Case Report and Review of the Literature

Case Reports in Oncology, 2021
Germline RUNX1 mutations lead to a rare form of autosomal-dominant familial thrombocytopenia with a predisposition for myeloid malignancies and are classified as distinct entities by the WHO.
Nabin Karki, Natasha Savage, Abdullah Kutlar   +2 more
doaj   +1 more source

23rd Congress of the European Hematology Association Stockholm, Sweden, June 14‐17, 2018

, 2018
HemaSphere, Volume 2, Issue S1, Page 1-1113, June 2018.
wiley   +1 more source

Accurate automated diagnosis of B-acute lymphoblastic leukemia using deep learning and flow cytometry

Haematologica
Not available.
Sulov Chalise, Mikhail Roshal, Sophia Roshal, Jeeyeon Baik, Qi Gao, Anyi Li, Ahmet Dogan, Harini Veeraraghavan, Meng-Lei Zhu   +8 more
doaj   +1 more source

A novel spliced fusion of MLL with CT45A2 in a pediatric biphenotypic acute leukemia [PDF]

, 2010
Background: Abnormalities of 11q23 involving the MLL gene are found in approximately 10% of human leukemias. To date, nearly 100 different chromosome bands have been described in rearrangements involving 11q23 and 64 fusion genes have been cloned and ...
Meyer, Claus, Santos Joana, Claus Meyer, Lucília Norton, Susana Bizarro, Lisboa, Susana, Joana Santos, Cecília Correia, Lisboa Susana, Susana Lisboa, Meyer Claus, Teixeira Manuel R, Nuno Cerveira, Torres, Lurdes, Marschalek Rolf, Torres Lurdes, Norton Lucília, Correia, Cecilia, Pinheiro Manuela, Santos, Joana, Bizarro, Susana, Correia Cecília, Teixeira, Manuel R., Manuel R Teixeira, Pinheiro, Manuela, Cerveira Nuno, Marschalek, Rolf (Prof. Dr.), Rolf Marschalek, Lurdes Torres, Manuela Pinheiro, Cerveira, Nuno, Norton, Lucilia, Bizarro Susana   +32 more
core   +2 more sources

Funkcionális genomikai rendszer kidolgozása gyermekkori acut lymphoid leukémiában DNS és cDNS chip analízis valamint immunfenotipizálás alapján = Development of a novel functional genomic system in pediatric acute lymphoid leukemia based on DNA and cDNA chip analysis as well as immunophenotyping [PDF]

, 2007
Olyan molekuláris markerek genomikai identifikálását tűztük ki célul, melyek a gyermekkori akut limfoid leukémia (ALL) patomechanizmusának felderítésében, osztályzásának pontosításában és a kezelésre adott válasz predikciójában szerepet játszhatnak.
Falus, András, Pállinger, Éva, Kovács, Gábor, Fekete, György, Erdélyi, Dániel   +4 more
core   +1 more source

Unveiling the omics tapestry of B-acute lymphoblastic leukemia: bridging genomics, metabolomics, and immunomics

Scientific Reports
Acute B-lymphoblastic leukemia (B-ALL) is a highly heterogeneous hematologic malignancy, characterized by significant molecular differences among patients as the disease progresses.
Yin Le, Shicong Zhu, Hongling Peng, Zhihua Wang   +3 more
doaj   +1 more source

Post-Induction Remission Status in B-Acute Lymphoblastic Leukemia Patients (B-ALL),  Experience at Tertiary Care Hospital

Pakistan Armed Forces Medical Journal
Objectives: To determine the frequency of post-induction remission status and its association with cytogenetic and molecular abnormalities in patients with B-ALL. Study Design: Cross-sectional Analytical study.
Sumaira Ilyas, Helen Mary Robert, Zahoor Hussain, Intzar Ali, Ayesha Wahid, Zara Zafar   +5 more
doaj   +1 more source

Allosteric inhibition enhances the efficacy of ABL kinase inhibitors to target unmutated BCR-ABL and BCR-ABL-T315I [PDF]

, 2012
Background: Chronic myelogenous leukemia (CML) and Philadelphia chromosome-positive (Ph+) acute lymphatic leukemia (Ph + ALL) are caused by the t(9;22), which fuses BCR to ABL resulting in deregulated ABL-tyrosine kinase activity.
Ruimi, Nili, Martin Ruthardt, Mahajna, Jamal, Khateb, Mamduh, Jamal Mahajna, Ruthardt, Martin, Ottmann, Oliver G., Oliver Gerhard Ottmann, Mian, Afsar Ali, Nili Ruimi, Yousef Najajreh, Afsar Ali Mian, Ottmann, Oliver Gerhard, Susanne Badura, Metodieva, Anna, Najajreh, Yousef, Anna Metodieva, Mamduh Khateb, Badura, Susanne   +18 more
core   +2 more sources

Minimal residual disease detection in Tunisian B-acute lymphoblastic leukemia based on immunoglobulin gene rearrangements

Brazilian Journal of Medical and Biological Research
IGH gene rearrangement and IGK-Kde gene deletion can be used as molecular markers for the assessment of B lineage acute lymphoblastic leukemia (B-ALL).
S. Besbes, W.S. Hamadou, M.L. Boulland, Y.B. Youssef, B. Achour, H. Regaieg, A. Khelif, T. Fest, Z. Soua   +8 more
doaj   +1 more source

MTHFR Polymorphisms In Childhood Acute lymphoblastic Leukemia: Influence On Methotrexate Therapy [PDF]

, 2017
Methotrexate (MTX) is an important component in the therapy used to treat childhood acute lymphoblastic leukemia (ALL). Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme for MTX pharmacokinetics.
Gutiérrez Camino, Ángela, Muñoz Maldonado, Carmen, Umerez, Maitane, Umerez Igartua, Maitane, Martín Guerrero, Idoia, García-Orad Carles, África   +5 more
core   +1 more source