Results 91 to 100 of about 33,886 (209)

Depletion of p75NTR in Schwann Cells Driven by Inflammation Mediates Cutaneous Pain in Psoriasis

Advanced Science, EarlyView.
Psoriasis‐like inflammation induces proliferation and molecular remodeling of cutaneous Schwann cells, marked by reduced p75NTR and increased NGF expression. IL‐17A promotes this process, whereas Schwann cell‐specific p75NTR overexpression alleviates cutaneous pain in vivo.
Yibo Wang, Linlin Xu, Chenglong Pan, Ruonan Cao, Piao Zeng, Xinxing Lyu, Qingxia Hu, Zhenzhen Yan, Shuhong Huang, Ningning Dang   +9 more
wiley   +1 more source

The role of sonography in early diagnosis of biliary complications in orthotopic liver transplantation

Трансплантология (Москва), 2018
The results of multiple complex ultrasound examinations performed in 180 patients after the OLT in early and late postoperative period are analyzed.
L. V. Donova, A. O. Chugunov, K. R. Dzhagraev   +2 more
doaj   +1 more source

Inactivating mutations in genes encoding for components of the BAF/PBAF complex and immune-checkpoint inhibitor outcome

Biomarker Research, 2020
Alterations of genes encoding subunits of the BAF/PBAF complexes are among the most frequent gene aberrations in human cancer. Such alterations have been shown to have an impact on tumor microenvironnement and on the capacity of tumors to respond to ...
Kevin Courtet, Yec’han Laizet, Carlo Lucchesi, Alban Bessede, Antoine Italiano   +4 more
doaj   +1 more source

Non-canonical role for the BAF complex subunit DPF3 in mitosis and ciliogenesis.

J Cell Sci
ABSTRACT DPF3, along with other subunits, is a well-known component of the BAF chromatin remodeling complex, which plays a key role in regulating chromatin remodeling activity and gene expression. Here, we elucidated a non-canonical localization and role for DPF3.
Verrillo G, Obeid AM, Genco A, Scrofani J, Orange F, Hanache S, Mignon J, Leyder T, Michaux C, Kempeneers C, Bricmont N, Herkenne S, Vernos I, Martin M, Mottet D.   +14 more
europepmc   +5 more sources

Electronic and Magnetic Structures of Chain Structured Iron Selenide Compounds

, 2012
Electronic and magnetic structures of iron selenide compounds Ce2O2FeSe2 (2212\ast) and BaFe2Se3(123\ast) are studied by the first-principles calculations.
A Krzton-Maziopa, A Krzton-Maziopa, B Saparov, C Cao, C Cao, E E McCabe, G Kresse, H Lei, I A Nebrasov, I R Shein, J Guo, J M Caron, J M Caron, J P Hu, J P Hu, J P Perdew, L Pourovskii, M A McCarron III, M Fang, M Wang, O J Lipscombe, P E Blöchl, P Zavalij, R H Liu, T Nakano, T Qian, T Siegrist, V Yu Pomjakushin, W Bao, W Li, X W Yan, X W Yan, Y Zhang, Z G Chen, Z Wang   +34 more
core   +1 more source

Sono‐Mechanogenetics: Linking Ultrasound Physics With Cellular Mechanobiology

Advanced Science, EarlyView.
Sono‐mechanogenetics links ultrasound physics with cellular mechanotransduction to enable noninvasive control of engineered biological systems. Acoustic forces generate distinct deformation modes that activate intracellular signaling pathways, which can be coupled to synthetic gene circuits to regulate diverse cellular functions, including gene ...
Yunjia Qu, Fan Wei, Chi Woo Yoon, Qifa Zhou, Yingxiao Wang   +4 more
wiley   +1 more source

SNF5 is an essential executor of epigenetic regulation during differentiation. [PDF]

PLoS Genetics, 2013
Nucleosome occupancy controls the accessibility of the transcription machinery to DNA regulatory regions and serves an instructive role for gene expression.
Jueng Soo You, Daniel D De Carvalho, Daniel D De Carvalho, Chao Dai, Minmin Liu, Kurinji Pandiyan, Xianghong J Zhou, Gangning Liang, Peter A Jones   +8 more
doaj   +1 more source

High‐Performance X‐Band Electromagnetic Interference Shielding in Flexible Barium Hexaferrite/Cobalt‐Based Microwires/Silicone Rubber Ternary Composites via Magnetic–Conductive Synergy

Advanced Electronic Materials, EarlyView.
A flexible ternary composite combining barium hexaferrite (BHF), Co–Microwires, and silicone rubber exploits magnetic–conductive synergy to deliver tunable X‐band EMI shielding, reaching a 16.9 dB at 9.8 GHz (surpassing the 10 dB industrial benchmark). Shielding behavior shifts between reflection and absorption with BHF loading and Co–Microwires counts
Moustafa A. Darwish, Marwa Karim, Azim Uddin, Sherif G. Elsharkawy, Mohamed M. Salem   +4 more
wiley   +1 more source

Comprehensive synergy mapping links a BAF- and NSL-containing “supercomplex” to the transcriptional silencing of HIV-1

Cell Reports, 2023
Summary: Host repressors mediate HIV latency, but how they interactively silence the virus remains unclear. Here, we develop “reiterative enrichment and authentication of CRISPRi targets for synergies (REACTS)” to probe the genome for synergies between ...
Zichong Li, Steven G. Deeks, Melanie Ott, Warner C. Greene   +3 more
doaj   +1 more source

De Novo Complex Genomic Rearrangement Spanning 2q31.1 in a Proband With Congenital Malformations: Genotype–Phenotype Correlation and Development of a CGR Detection Pipeline

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The 2q31 region is commonly associated with pathogenic alleles of the HOXD cluster leading to various clinical phenotypes related to skeletal development. We present a proband with tetralogy of Fallot and multiple congenital anomalies. Genomic variant screening including an in‐house CGR detection pipeline pairing genome sequencing (GS ...
Katherine Helle, Jesse D. Bengtsson, Mira Gandhi, Christopher M. Grochowski, Ming Yin Lun, Neha Sudhir, Shalini N. Jhangiani, Fritz J. Sedlazeck, Seema R. Lalani, Neil A. Hanchard, Claudia M. B. Carvalho   +10 more
wiley   +1 more source