Results 81 to 90 of about 9,962 (180)

Baicalein inhibits PRRSV through direct binding, targeting EGFR, and enhancing immune response

Veterinary Research
Porcine reproductive and respiratory syndrome virus (PRRSV) presents significant economic challenges to the global pork industry due to its ability to mutate rapidly.
Jing Wu, Qi Lu, Jing Hou, Yueqin Qiu, Min Tian, Li Wang, Kaiguo Gao, Xuefen Yang, Zongyong Jiang   +8 more
doaj   +1 more source

Antibacterial activity of baicalein against Aeromonas hydrophila: in vitro and in vivo evaluation

Frontiers in Microbiology
IntroductionAeromonas hydrophila (AH) is a pathogenic bacterium commonly found in aquatic organisms, particularly in fish products. Baicalein, a bioactive flavonoid derived from traditional Chinese herbal medicine, possesses a wide range of ...
Reng Qiu, Jun Li, Changjun Jiang, Yang Yu, Dandan Li, Xuehan Xie, Yang Lei, Lunguang Yao   +7 more
doaj   +1 more source

The anti-metastatic effect of baicalein on colorectal cancer

Oncology Reports, 2017
Baicalein, a naturally occurring flavonoid isolated from the roots of Scutellaria baicalensis, is historically and widely used as anti-inflammatory and anticancer therapy. Nevertheless, the anti-metastatic effect and underlying molecular mechanisms of baicalein on colorectal carcinoma (CRC) remain unclear.
Yuxia, Chai, Jizhong, Xu, Baojun, Yan
openaire   +3 more sources

Comparison of metabolic pharmacokinetics of baicalin and baicalein in rats

Journal of Pharmacy and Pharmacology, 2003
Abstract Baicalin and baicalein, a flavone glucuronide and its aglycone, are bioactive constituents of Scutellariae Radix with various beneficial activities. We have characterized and compared the metabolic pharmacokinetics of baicalin and baicalein in rats.
Miao-Ying, Lai, Su-Lan, Hsiu, Shang-Yuan, Tsai, Yu-Chi, Hou, Pei-Dawn Lee, Chao   +4 more
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Baicalein suppresses metastasis of breast cancer cells by inhibiting EMT via downregulation of SATB1 and Wnt/β-catenin pathway

Drug Design, Development and Therapy, 2016
Xingcong Ma,1 Wanjun Yan,1 Zhijun Dai,1 Xiaoyan Gao,1 Yinan Ma,1 Quntao Xu,2 Jiantao Jiang,3 Shuqun Zhang11Department of Oncology, the Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, People's Republic of China ...
Ma X, Yan W, Dai Z, Gao X, Ma Y, Xu Q, Jiang J, Zhang S   +7 more
doaj  

Baicalein combined with azoles against fungi in vitro

Frontiers in Microbiology
BackgroundInvasive fungal infections (IFIs) constitute a significant health challenge, particularly among immunocompromised individuals, characterized by a high prevalence and associated mortality rates. The synergistic administration of Baicalein (BE) with azole antifungal agents could potentially herald a novel therapeutic paradigm.Materials and ...
Mengmin Liang, Qingwen Hu, Junhao Yu, Heng Zhang, Sijie Liu, Jiangrong Huang, Yi Sun   +6 more
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Baicalein Sensitizes Triple Negative Breast Cancer Cells to Cisplatin by Activating Apoptosis

Natural Product Communications
Objective/background The potential for natural products to work synergistically with chemotherapy to reduce side effects and enhance its effectiveness has garnered significant attention.
Aya Y. Al-Kabariti, Manal A. Abbas, Moath Alqaraleh, Razan Madi, Steven D. Shnyder   +4 more
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Baicalein induces apoptosis and autophagy of breast cancer cells via inhibiting PI3K/AKT pathway in vivo and vitro

Drug Design, Development and Therapy, 2018
Wanjun Yan, Xingcong Ma, Xiaoyao Zhao, Shuqun Zhang Department of Oncology, The Second Affiliated Hospital, Xi’an Jiaotong University, Xi’an, China Purpose: Baicalein, a widely used Chinese herbal medicine, has shown anticancer effects on ...
Yan W, Ma X, Zhao X, Zhang S
doaj  

Baicalein: unveiling the multifaceted marvel of hepatoprotection and beyond

Journal of Asian Natural Products Research
Flavonoids are bioactive compounds derived from plants that play a crucial role in human health. Baicalein is a prominent phytoconstituent with multifaceted therapeutic potential against various diseases. This review explores recent advancements in understanding baicalein’s hepatoprotective action against different toxicity models (acetaminophen ...
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Natural Flavonoids Genistein and Baicalein as Well-Tolerated Radiosensitizers to Enhance the Efficacy of ¹⁷⁷Lu-PSMA617 in Prostate Cancer: In Vitro and In Vivo Studies. [PDF]

Research (Wash D C)
He C, Shao Y, Bao Y, Li J, Si H, He J.
europepmc   +1 more source