Results 71 to 80 of about 9,962 (180)
Obesity Science &Practice, Volume 12, Issue 4, August 2026.In this study, we explore the effects of Modified Lingguizhugan Decoction (MLGZGD) on obesity and lipid metabolism in mice, using a multi‐omics approach. Our results show that MLGZGD modulates gut microbiota composition, including beneficial genera like Akkermansia, and improves lipid metabolism by regulating triglyceride and phosphatidylcholine levels.
Fufu Li +9 more
wiley +1 more source
Acta Crystallographica Section C, Volume 82, Issue 8, Page 414-426, August 2026.The tendency for alkaloid–flavonoid cocrystal formation is found to be markedly different for theophylline (Tph) compared to its 8‐halo analogues. Through screening with 13 common flavonoids, Tph is found to form cocrystals with six flavonoids, whereas 8‐Cl‐Tph and 8‐Br‐Tph each form cocrystals with just two, myricetin and kaempferol.
Weijian Ye +2 more
wiley +1 more source
Baicalein Prevents 6-Hydroxydopamine-Induced Dopaminergic Dysfunction and Lipid Peroxidation in Mice
Journal of Pharmacological Sciences, 2005 The effects of baicalein on 6-hydroxydopamine (6-OHDA)-induced neurotoxicity were evaluated. Intracerebroventricularly (i.c.v.) injection of 6-OHDA was done to young mice. Baicalein was administered intraperitoneally 30 min before and 90 min after i.c.v.
Heh-In Im +5 more
doaj +1 more source
Chemokines in Alzheimer's Disease: Early Defence, Late Damage and the Impact of Sex and Infection
Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 2, August 2026.ABSTRACT Chemokines constitute a versatile signalling network maintaining homeostasis and glia–neuron communication in the healthy brain but become progressively dysregulated during aging and Alzheimer's disease (AD). This review examines how chemokine systems transition from tightly regulated homeostatic signals to drivers of chronic neuroinflammation
Blanca I. Aldana, Kristine Freude
wiley +1 more source
Interaction of baicalin and baicalein with antibiotics in the gastrointestinal tract
Journal of Pharmacy and Pharmacology, 2005 Abstract To clarify the absorption mechanism of baicalin and to investigate the interaction between baicalin and antibiotics, the pharmacokinetics of baicalin and its aglycone baicalein in normal rats and in antibiotic-treated (with a mixture of neomycin and streptomycin) rats were investigated.
Jie, Xing +4 more
openaire +2 more sources
Baicalein improves renal interstitial fibrosis by inhibiting the ferroptosis in vivo and in vitro
HeliyonEvidence indicates that Baicalein can ameliorate renal interstitial fibrosis by inducing myofibroblast apoptosis and inhibit the RLS3-induced ferroptosis in melanocytes.
Guo-qiang Liang, Wei Mu, Chun-bo Jiang
doaj +1 more source
Drug Design, Development and Therapy, 2022 Dongli Guo, Jing Jin, Jianghui Liu, Yingying Wang, Daojuan Li, Yutong He Cancer Institute, Fourth Hospital of Hebei Medical University, Shijiazhuang, People’s Republic of ChinaCorrespondence: Yutong He, Fourth Hospital of Hebei Medical University, No. 12,
Guo D, Jin J, Liu J, Wang Y, Li D, He Y
doaj
Frontiers in Pharmacology, 2018 The dermis of human skin contains large numbers of fibroblasts that are responsible for the production of the extracellular matrix (ECM) that supporting skin integrity, elasticity and wound healing.
Chien-Liang Fang +3 more
doaj +1 more source
Open Life SciencesGestational diabetes mellitus (GDM) is a common metabolic disorder during pregnancy characterized by glucose intolerance, which poses risks to both maternal and fetal health. Baicalein, a flavonoid derived from the roots of Scutellaria baicalensis Georgi,
Yao Jun +4 more
doaj +1 more source
Frontiers in Pharmacology, 2019 Introduction: Ulcerative colitis (UC) is an inflammatory bowel disease with a high incidence rate and a difficult treatment regimen. Recently, significant advances in the treatment of intestinal diseases, particularly UC, have been made with the use of ...
Shuai Liang +10 more
doaj +1 more source