Results 21 to 30 of about 20,980 (270)

Inhibitory effect of baicalin on Streptococcus mutans UA159 in vitro

口腔疾病防治, 2021
Objective To investigate the inhibitory effect of baicalin on Streptococcus mutans UA159 in vitro.Methods The minimum inhibitory concentration (MIC) of baicalin on Streptococcus mutans UA159 was determined by the liquid multiple dilution method combined ...
WU Ju, WANG Ling, LIU Xingrong
doaj   +1 more source

Baicalin Promotes Mammary Gland Development via Steroid-Like Activities

Frontiers in Cell and Developmental Biology, 2021
Baicalin, the main flavonoid component extracted from Scutellaria roots, has a variety of biological activities and is therefore used in the treatment of many kinds of diseases.
Weizhen Chen, Wei Wei, Liya Yu, Xin Zhang, Fujing Huang, Qiping Zheng, Qiping Zheng, Lingli Wang, Cheguo Cai, Cheguo Cai, Cheguo Cai   +10 more
doaj   +1 more source

Antiviral effect of baicalin on Marek’s disease virus in CEF cells

BMC Veterinary Research, 2020
Background Baicalin, the main metabolic component of Scutellaria baicalensis Georgi, has various pharmacological properties including anti-inflammatory, anti-oxidant, anti-apoptotic, anti-bactericidal and anti-viral.
Fan Yang, Chun Feng, Yongxiu Yao, Aijian Qin, Hongxia Shao, Kun Qian   +5 more
doaj   +1 more source

Chemoprotective effect of baicalin against cyclophosphamide induced ovarian toxicity in mice via inhibition of TGF-β

Heliyon, 2023
Ovarian toxicity is most common gynecologically related malignancy, arising for most cases owing to the advanced stage of diagnosis. The aim of the current study was to explore the anticancer potential of baicalin against cyclophosphamide (CP) induced ...
Xuefeng Li, Juan Yue, Yogesh Kumar, Yannan Ma   +3 more
doaj   +1 more source

Baicalin administration attenuates hyperglycemia-induced malformation of cardiovascular system [PDF]

, 2018
In this study, the effects of Baicalin on the hyperglycemia-induced cardiovascular malformation during embryo development were investigated. Using early chick embryos, an optimal concentration of Baicalin (6 μM), was identified which could prevent ...
A Dugaiczyk, A Ejdesjo, AC Tufan, C Li, CC Lin, CD Bortner, CZ Wang, D Henrique, D Song, E Maeno, EL Abel, F Tepekoy, F Wang, F Yin, G Wang, G Wang, HT Trinh, JS Baek, K Ishimaru, K Noh, KE Yutzey, KK Linask, L Xu, M Li-Weber, M Maroto, MJ Kang, MR Oliveira de, P Wang, R Haribalaganesh, S Patan, SC Chapman, SS Han, T Brand, T Khanal, TM Schultheiss, V Hamburger, X Cheng, X Qi, XY Tian, Y Hasegawa, Y Jin, Y Li, Y Li, Y Nakajima, Y Nakajima, YM Jin, YM Zhang, YQ He   +47 more
core   +4 more sources

Autophagy-induced RelB/p52 activation mediates tumour-associated macrophage repolarisation and suppression of hepatocellular carcinoma by natural compound baicalin [PDF]

, 2015
Open Access JournalThe plasticity of tumour-associated macrophages (TAMs) has implicated an influential role in hepatocellular carcinoma (HCC). Repolarisation of TAM towards M1 phenotype characterises an immune-competent microenvironment that favours ...
Che, CM, Feng, Y, Man, K, TAN, HY, Tsao, GSW, Wang, N   +5 more
core   +1 more source

Baicalin relieves hypoxia-aroused H9c2 cell apoptosis by activating Nrf2/HO-1-mediated HIF1α/BNIP3 pathway

Artificial Cells, Nanomedicine, and Biotechnology, 2019
Background Myocardial ischemia is the main reason for ischemic heart disease. Baicalin is a plant-derived flavonoid with cardio-protective activity.
Hailiang Yu, Bin Chen, Qi Ren
doaj   +1 more source

Baicalin Induces Apoptosis in SW620 Human Colorectal Carcinoma Cells in Vitro and Suppresses Tumor Growth in Vivo

Molecules, 2012
In the United States, colorectal cancer (CRC) is the second most frequent malignancy and the fourth most common cause of cancer death. Baicalin, a flavone derivative isolated and purified from the dry root of Scutellaria, was assessed for its antitumor ...
Yi-Shiuan Tzeng, Ying-Chieh Tsai, Tsu-Hsiang Kuo, Wen-Cheng Chen   +3 more
doaj   +1 more source

Baicalin regulates macrophages polarization and alleviates myocardial ischaemia/reperfusion injury via inhibiting JAK/STAT pathway

Pharmaceutical Biology, 2020
Context Baicalin is an active compound which demonstrates cardioprotection effects against myocardial ischaemia/reperfusion injury (MI/RI). Objective To investigate how baicalin protects against myocardial injury and to explore its potential mechanism ...
Ming Xu, XiaoYong Li, Laichun Song
doaj   +1 more source

Baicalin attenuates lipopolysaccharide-induced pro-inflammatory cytokine expression in murine macrophage cell line RAW264.7 through miR-124-STAT3 axis

European Journal of Inflammation, 2018
Baicalin, a flavonoid isolated from Scutellaria baicalensis Georgi, has shown a wide range of anti-inflammatory, antioxidative, antiviral, and antitumor properties.
Bin Tang, Xixi Wang, Yuqing Zhu, Xuhui Li, Shukun Yao   +4 more
doaj   +1 more source