Results 41 to 50 of about 26,861 (248)

Bonding mechanism in the nitrides Ti2AlN and TiN: an experimental and theoretical investigation

, 2007
The electronic structure of nanolaminate Ti2AlN and TiN thin films has been investigated by bulk-sensitive soft x-ray emission spectroscopy. The measured Ti L, N K, Al L1 and Al L2,3 emission spectra are compared with calculated spectra using ab initio ...
A. Grechnev, C. Höglund, D. G. Watson, G. Hägg, J. M. Wills, J.-E. Sundgren, K. Ichikawa, L. Hultman, M. Beckers, M. Magnuson, M. Mattesini, M. Y. Gamarnik, O. Eriksson, R. Denecke, S. Li   +14 more
core   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

A family of balanced ternary designs with block size four [PDF]

Bulletin of the Australian Mathematical Society, 1986
This paper shows the existence of an infinite family of cyclic balanced ternary designs where the block size is 4, the index 2 and each block contains precisely one repeated element.
openaire   +2 more sources

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

The Multi‐Functional Third Acceptor Realizes the Synergistic Improvement in Photovoltaic Parameters and the High‐Ratio Tolerance of Ternary Organic Photovoltaics

Advanced Science
The ternary strategy proves effective for breakthroughs in organic photovoltaics (OPVs). Elevating three photovoltaic parameters synergistically, especially the proportion‐insensitive third component, is crucial for efficient ternary devices.
Yuhao Liu, Lingling Zhan, Zhongjie Li, Hang Jiang, Huayu Qiu, Xiaokang Sun, Hanlin Hu, Rui Sun, Jie Min, Jinyang Yu, Weifei Fu, Shouchun Yin, Hongzheng Chen   +12 more
doaj   +1 more source

Physico-mechanical and microstructural investigation of a fly ash-based geopolymer and an inorganic waste blend-reinforced fly ash-based geopolymer pastes: A comparative study

Next Materials
The high carbon emissions associated with ordinary Portland cement production have intensified the search for sustainable and low-impact alternatives in the construction sector.
Badr Aouan, Hamid Saufi, Marouane El Alouani, Mariem Ben Tourtit, Kawtar Boukaddour, Wafaa Ahmina, Fadoua El Makhoukhi, Saliha Alehyen   +7 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

CONSTRUCTION METHOD OF A-OPTIMAL CHEMICAL BALANCE WEIGHING DESIGNS

Acta Universitatis Lodziensis. Folia Oeconomica, 2015
Here, we study the design in that we determine unknown measurements of p objects by used of n measurement operations. For that reason we consider the chemical balance weighing design under assumption that the measurement errors are uncorrelated and they ...
Bronisław Ceranka, Małgorzata Graczyk
doaj  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source