Results 91 to 100 of about 3,228 (214)

Mitochondrial Dysfunction in Aristolochic Acid I-Induced Kidney Diseases: What We Know and What We Do Not Know

Applied Sciences
Aristolochic acids, compounds derived from Aristolochiaceae plant species, are associated with significant renal nephrotoxicity and carcinogenicity. Aristolochic acid I (AAI), the most predominant and potent of these compounds, is a primary etiological ...
Alexandra T. Lukinich-Gruia, Crenguta L. Calma, Flavia A. E. Szekely, Iustina-Mirabela Cristea, Maria-Alexandra Pricop, Alina-Georgiana Simina, Valentin L. Ordodi, Nikola M. Pavlović, Calin A. Tatu, Virgil Paunescu   +9 more
doaj   +1 more source

Dominant-Negative Effect of a Missense Variant in the TASK-2 (KCNK5) K+ Channel Associated with Balkan Endemic Nephropathy.

PLoS ONE, 2016
TASK-2, a member of the Two-Pore Domain (K2P) subfamily of K+ channels, is encoded by the KCNK5 gene. The channel is expressed primarily in renal epithelial tissues and a potentially deleterious missense variant in KCNK5 has recently been shown to be ...
Alan P Reed, Giovanna Bucci, Firdaus Abd-Wahab, Stephen J Tucker   +3 more
doaj   +1 more source

Endemic Nephropathy Around the World

Kidney International Reports, 2017
There have been several global epidemics of chronic kidney disease of unknown etiology (CKDu). Some, such as Itai-Itai disease in Japan and Balkan endemic nephropathy, have been explained, whereas the etiology of others remains unclear. In countries such
Fiona J. Gifford, Robert M. Gifford, Michael Eddleston, Neeraj Dhaun   +3 more
doaj   +1 more source

Poster Sessions

HemaSphere, Volume 9, Issue S1, June 2025.
wiley   +1 more source

Unambiguous detection of multiple TP53 gene mutations in AAN-associated urothelial cancer in Belgium using laser capture microdissection.

PLoS ONE, 2014
In the Balkan and Taiwan, the relationship between exposure to aristolochic acid and risk of urothelial neoplasms was inferred from the A>T genetic hallmark in TP53 gene from malignant cells.
Selda Aydin, Anne-France Dekairelle, Jérôme Ambroise, Jean-François Durant, Michel Heusterspreute, Yves Guiot, Jean-Pierre Cosyns, Jean-Luc Gala   +7 more
doaj   +1 more source

Geographic distribution and risk of upper urothelial carcinomas in Croatia, 2001–2011

BMC Cancer, 2019
Background Strong associations exist between Balkan endemic nephropathy (BEN) and upper urothelial carcinomas (UUCs). However, the common etiology between the two remains unclear and there are no studies to date that visualize UUC risks in Croatia.
Danira Medunjanin, Zdenko Sonicki, John E. Vena, Ante Cvitkovic, Sara Wagner Robb   +4 more
doaj   +1 more source

Nephroprotective role of resveratrol and ursolic acid in aristolochic acid intoxicated zebrafish [PDF]

[[incitationindex]]SCI[[booktype ...
[[corresponding]]Chen YH, Ding YJ, Sun CY, Wen CC, Chen YH   +1 more
core  

Results of mycological and mycotoxicological investigations of corn-based feed for dairy cow diet [PDF]

In this study, fungal contamination was determined as well as total aflatoxin B1(AB1), ochratoxin A (OTA) and zearalenon (ZEA) levels in corn-based feed samples obtained from four different farms in Serbia (n=35) during one year. Mycotoxins were
Blagojev Nevena, Gerić Tamara, Jakić-Dimić Dobrila, Vesković-Moračanin Slavica, Škrinjar Marija, Šošo Vladislava   +5 more
core   +1 more source

Values of Alpha 1 Microglobulin Does Not Differ between Individuals with and without Family History of Balkan Endemic Nephropathy

International Journal of Nephrology, 2014
Aim. The aim of this study was to compare urinary alpha 1 microglobulin (A1MG) in healthy individuals with and without family burden for Balkan endemic nephropathy (BEN) in an endemic village. Methods. Otherwise healthy inhabitants with microalbuminuria
Mirna Aleckovic-Halilovic, Enisa Mesic, Senaid Trnacevic, Emir Hodzic, Vildana Habul, Mirza Atic, Maida Dugonjic, Evlijana Hasanovic   +7 more
doaj   +1 more source

EHA2024 Hybrid Congress

HemaSphere, Volume 8, Issue S1, June 2024.
wiley   +1 more source