Bypassing BamD essentiality by mutations in a non-essential substrate [PDF]
The β-barrel assembly machinery (Bam) is essential for assembling all transmembrane β-barrel outer membrane proteins in gram-negative bacteria. The Bam complex consists of the central β-barrel protein BamA and accessory Bam lipoproteins, including the ...
Santosh Kumar, Anna Konovalova
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Targeting Proteus mirabilis BAM Complex Proteins for Development of Novel Antibiotics [PDF]
Urinary tract infections (UTIs) are frequent hospital-acquired infection, with Escherichia coli and Proteus mirabilis accounting for 90% of complicated UTIs. Emergence of multidrug-resistant (MDR) bacteria have complicated the treatment UTIs. P. mirabilis related UTIs has been associated with the production of urinary stones and long-term infections in
Raphael Abban +4 more
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Native β-barrel substrates pass through two shared intermediates during folding on the BAM complex. [PDF]
Dos Santos TMA +5 more
europepmc +3 more sources
Outer membrane protein assembly mediated by BAM-SurA complexes [PDF]
AbstractThe outer membrane is a formidable barrier that protects Gram-negative bacteria against environmental threats. Its integrity requires the correct folding and insertion of outer membrane proteins (OMPs) by the membrane-embedded β-barrel assembly machinery (BAM).
Katherine Fenn +8 more
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Structure of a nascent membrane protein as it folds on the BAM complex. [PDF]
Mitochondria, chloroplasts and Gram-negative bacteria are encased in a double layer of membranes. The outer membrane contains proteins with a β-barrel structure1,2. β-Barrels are sheets of β-strands wrapped into a cylinder, in which the first strand is hydrogen-bonded to the final strand. Conserved multi-subunit molecular machines fold and insert these
Tomasek D +6 more
europepmc +5 more sources
Performance Analysis of a Novel Cross-flow Solar Air Heater with Square Perforated Absorber Plate: An Experimental Study [PDF]
The current study introduces and analyzes a novel square cross-flow perforated solar air heater (SAH). Since the convection mechanism in SAHs is weak, numerous methods have been suggested to address this problem and improve thermal efficiency ...
H. Farzan +2 more
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Bacterial Outer Membrane Proteins Are Targeted to the Bam Complex by Two Parallel Mechanisms. [PDF]
Proteins that are embedded in the outer membrane of Gram-negative bacteria (OMPs) play an important role in protecting the cell from harmful chemicals. OMPs share a architecture and often contain a conserved sequence motif (β motif) of unknown function.
Wang X, Peterson JH, Bernstein HD.
europepmc +4 more sources
Performance of New Absorber Coating Strategy in Solar Air Heaters: An Experimental Case Study [PDF]
Asphalt materials commonly have high absorption coefficients, and their surface temperature reaches as high as 80 oC during daytime hours since their surfaces are exposed to solar radiation for long periods.
M. Mahmoudi, H. Farzan, E. Hasan Zaim
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An Investigating the effect of economic and social factors on Iran's ecological footprint Using the Markov switching- Error Correction Model [PDF]
Todays, environmental pollution is one of the main challenges of the world and global economic growth is causing environmental degradation. Therefore, considering the purpose of economic growth and its impact on ecological footprint, it is important to ...
Maryam Ziaabadi +2 more
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Identification and Strategic Planning for Entrepreneurship Skills of Biotechnology Graduates Case Study: Shahid Bahonar University of Kerman [PDF]
Objective Biotechnology is one of the most important technologies in particular novelty ones that has many applications in entrepreneurship and knowledge-based businesses.
Salimeh Ghanbari, Maryam Ziaabadi
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