Results 41 to 50 of about 4,718,015 (356)

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Az erőszak elmélete Leninnél és megvalósításának egyes fázisai a gyakorlatban

open access: yesAxis
Az erőszak az emberi történelemmel egyidős jelenség. Rengeteg formáját, megjelenését, típusát ismerjük, látjuk, halljuk és tapasztaljuk jelenünkben is.
Bank Barbara
doaj   +1 more source

Pacific Economic Monitor: Budget Analysis [PDF]

open access: yes, 2014
The Monitor provides an update of developments in Pacific economies and explores topical policy ...
Asian Development Bank
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Office of Anticorruption and Integrity: Annual Report 2013 [PDF]

open access: yes, 2014
[Excerpt] Corruption is not single-celled. It does not move in just one direction and has many causes and symptoms. It has no single cure and will continue to grow and fester unless addressed from multiple fronts.
Asian Development Bank
core   +1 more source

Keep walking? Geographical proximity, religion, and relationship banking [PDF]

open access: yes, 2018
We investigate the geographical proximity of firms to their relationship banks. We find that Islamic banks are more remote to their borrowers. We also find that the probability for a firm to connect to a bank substantially decreases in distance, but that
Beck, T.   +2 more
core   +2 more sources

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

TRATADOS INTERNACIONALES DE DERECHOS HUMANOS BAJO EL ORDENAMIENTO JURÍDICO ALEMÁN

open access: yesIus et Praxis, 2003
En el presente artículo el autor analiza la posición de los tratados internacionales en general, como asimismo, los tratados de derechos humanos y de integración en el sistema jurídico alemán, considerando la posición de la doctrina y la jurisprudencia ...
Roland Bank
doaj  

Good Banks and bad Banks, centralised Banks and local Banks and economic Growth

open access: yesEkonomiaz. Revista vasca de Economía, 2013
The on-going banking crisis has demonstrated the significance of banking for economic growth. While banks as creators of money are important for the functioning of the economy, bank lending to productive enterprises is necessary for economic activity.
Chick, Victoria   +2 more
openaire   +2 more sources

Contract Farming for Better Farmer-Enterprise Partnerships: ADB\u27s Experience in the People\u27s Republic of China [PDF]

open access: yes, 2015
[Excerpt] Agriculture should provide safe and nutritious food to people. In the People’s Republic of China (PRC ) and many other developing members of the Asian Development Bank (ADB), agriculture is also the main source of income for rural residents ...
Asian Development Bank
core   +1 more source

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