Results 41 to 50 of about 5,409,824 (379)
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
Gender Equality Results Case Study - Bangladesh: Second Urban Primary Health Care Project [PDF]
, 2015 Development Aims and Impacts. The Urban Primary Health Care Project strengthened and expanded primary health care infrastructure and services with a focus on the urban poor.
Asian Development Bank
core +1 more source
Bank Networks from Text: Interrelations, Centrality and Determinants [PDF]
, 2015 In the wake of the still ongoing global financial crisis, bank interdependencies have come into focus in trying to assess linkages among banks and systemic risk. To date, such analysis has largely been based on numerical data.
Rönnqvist, Samuel, Sarlin, Peter
core +2 more sources
Bank Resolution and the Structure of Global Banks [PDF]
The Review of Financial Studies, 2018 We study the resolution of global banks by national regulators. Single-point-of-entry (SPOE) resolution, where loss-absorbing capital is shared across jurisdictions, is efficient but faces implementation constraints. First, when expected transfers across jurisdictions are too asymmetric, national regulators fail to set up SPOE resolution ex ante ...
Patrick Bolton +2 more
openaire +5 more sources
Molecular Oncology, EarlyView.B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez +17 more
wiley +1 more source
Obesity and cancer: the gammadelta T cell link
Exploration of Immunology, 2022 Obesity has become a worldwide scourge, affecting more than 10% of adults worldwide. While widely recognized to be associated with increased incidence of medical conditions such as diabetes mellitus and atherosclerosis, obesity also accounts for 9% of ...
Ilan Bank
doaj +1 more source
, 2013 Beneath the gloss of Asia’s newfound prosperity lies an unsettling reality. Rising inequality has denied the benefits of Asia’s economic growth to many millions of its citizens.
Asian Development Bank
core +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
Gender Equality Results Case Study - Nepal: Community-Based Water Supply and Sanitation Sector Project [PDF]
, 2015 Development Aims and Impacts. The Community-Based Water Supply and Sanitation Sector Project aimed at expanding the coverage of improved water supply and sanitation facilities to poor and remote areas, and improving health and hygiene practices related ...
Asian Development Bank
core +1 more source
Molecular Oncology, EarlyView.Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho +11 more
wiley +1 more source