Results 101 to 110 of about 3,184,320 (288)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Depletion or over-expression of Sh3px1 results in dramatic changes in cell morphology

open access: yesBiology Open, 2015
The mammalian Sorting Nexin 9 (Snx9) family consists of three paralogs: Snx9, Snx18 and Snx33. Most of the published literature to date has centered on the role of Snx9 in clathrin-mediated endocytosis (CME). Snx9 contains an Sh3 domain at its N-terminus
Lawrence Hicks   +6 more
doaj   +1 more source

SNX9: An Unconventional Bar Domain Protein? [PDF]

open access: yesBiophysical Journal, 2021
Feng-Ching Tsai   +3 more
openaire   +1 more source

Lockwood Letter. (Toledo, Ohio), April 1986

open access: yes, 2019
The Lockwood Letter is a newspaper published by the Toledo Women's Bar Association published in part to "promote and advance the position of and opportunities available to women attorneys" in the Toledo ...
Toledo Women's Bar Association
core  

Coriolis effects and the thermal bar [PDF]

open access: yes, 2002
A model for the thermal bar system in the rotating frame that includes unsteady inertia is formulated. Asymptotic solutions are found to the initial value problem in the frictionless, small bottom slope limit.
Farrow, D.E.
core  

Syriac lexicon Hasan Bar Bahlul. Volume 2

open access: yes, 1886
The massive Syriac-Syriac/Arabic lexicon—actually more an encyclopedia than a mere lexicon—of Bar Bahlul (10th century) is one of two commonly cited Syriac dictionaries from the medieval period, the other being that of Bar Ali.

core   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

Proposed fault diagnostics of a broken rotor bar induction motor fed from PWM inverter

open access: yesJournal of Electrical Systems and Information Technology, 2016
This paper presents a fault diagnostics technique for a three-phase squirrel cage induction motor. The method is developed using a simplified model affected by bar resistance variation.
Faeka M.H. Khater   +3 more
doaj   +1 more source

Lockwood Letter. (Toledo, Ohio), Fall 1990

open access: yes, 2019
The Lockwood Letter is a newspaper published by the Toledo Women's Bar Association published in part to "promote and advance the position of and opportunities available to women attorneys" in the Toledo ...
Toledo Women's Bar Association
core  

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

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