Results 141 to 150 of about 3,963,937 (304)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Proceedings of the Grafton and Coös Counties Bar Association.
, 1887 Issued in parts, usually annually, with general title-pages and indexes at intervals of several years.Imprint varies.Title varies slightly.Issues for 1885/7-1897/8 called also v.
Grafton and Coös Bar Association.
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
, 1901 Mode of access: Internet.Later proceedings published in: Michigtan state bar journal.1901 bound with: Michigan State Bar Association. Official proceedings of the ...
Michigan State Bar Association.
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Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
An asymptotic model for the hydrodynamics of the thermal bar [PDF]
, 1995 An asymptotic solution is found for the temperature and circulation structure for an unsteady two-dimensional model of the thermal bar phenomenon. The non-rotating case considered here is relevant to laboratory models of the thermal bar.
Farrow, D.E.
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Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
A numerical model of the hydrodynamics of the thermal bar [PDF]
, 1995 The thermal bar phenomenon is modelled numerically by the natural convection of a fluid contained in a two-dimensional triangular domain. The non-rotating case considered here is appropriate to laboratory models of the thermal bar.
Farrow, D.E.
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Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source