Results 121 to 130 of about 3,963,937 (304)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Lockwood Letter. (Toledo, Ohio), August 1993
, 2019 The Lockwood Letter is a newspaper published by the Toledo Women's Bar Association published in part to "promote and advance the position of and opportunities available to women attorneys" in the Toledo ...
Toledo Women's Bar Association
core
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Lockwood Letter. (Toledo, Ohio), Summer 1987
, 2019 The Lockwood Letter is a newspaper published by the Toledo Women's Bar Association published in part to "promote and advance the position of and opportunities available to women attorneys" in the Toledo ...
Toledo Women's Bar Association
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Lockwood Letter. (Toledo, Ohio), April 1993
, 2019 The Lockwood Letter is a newspaper published by the Toledo Women's Bar Association published in part to "promote and advance the position of and opportunities available to women attorneys" in the Toledo ...
Toledo Women's Bar Association
core
Syriac lexicon Hasan Bar Bahlul. Volume 3
The massive Syriac-Syriac/Arabic lexicon—actually more an encyclopedia than a mere lexicon—of Bar Bahlul (10th century) is one of two commonly cited Syriac dictionaries from the medieval period, the other being that of Bar Ali.
core +1 more source
Coriolis effects and the thermal bar [PDF]
, 2002 A model for the thermal bar system in the rotating frame that includes unsteady inertia is formulated. Asymptotic solutions are found to the initial value problem in the frictionless, small bottom slope limit.
Farrow, D.E.
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Lockwood Letter. (Toledo, Ohio), March 1994
, 2019 The Lockwood Letter is a newspaper published by the Toledo Women's Bar Association published in part to "promote and advance the position of and opportunities available to women attorneys" in the Toledo ...
Toledo Women's Bar Association
core