Results 111 to 120 of about 35,038 (278)

Phenobarbital Bioequivalence in Chinese Population: Considering the Role of Food on Pharmacokinetics

open access: yesClinical Pharmacology in Drug Development, Volume 14, Issue 12, Page 925-933, December 2025.
Abstract Epilepsy is one of the most severe neurological disorders in the world, which might seriously endanger the lives of patients. Phenobarbital is an important medicine clinically used for the treatment of epilepsy, and it is irreplaceable in the treatment of generalized tonic–clonic seizures, focal seizures, status epilepticus, and pediatric ...
Wang Xinman   +3 more
wiley   +1 more source

Connections of the Mesencephalic Locomotor Region (MLR) in the Cat [PDF]

open access: yes, 1980
The cat entopeduncular nucleus (EN), which is the main output of the basal ganglia, is known to project to the mesencephalic tegmentum. We have been able to elicit antidromic responses in single EN neurons from the region of the mesencephalic locomotor ...
Garcia-Rill, E.   +2 more
core   +2 more sources

More on Barbiturate-related Hyperalgesia [PDF]

open access: bronze, 1995
Anand Tewari   +2 more
openalex   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Ion channels

open access: yesBritish Journal of Pharmacology, Volume 182, Issue S1, Page S152-S241, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander   +86 more
wiley   +1 more source

Prevalence and Duration of Potential Drug–Drug Interactions Among US Nursing Home Residents, 2018–2020

open access: yesJournal of the American Geriatrics Society, Volume 73, Issue 12, Page 3766-3777, December 2025.
ABSTRACT Background Nursing home (NH) residents are at increased risk of drug–drug interactions (DDIs) due to multimorbidity and polypharmacy. While prior research suggests that many DDIs lead to adverse drug events in older adults, the extent of exposure to potentially clinically relevant DDIs among United States (US) NH residents is largely unknown ...
Laura A. Reich   +9 more
wiley   +1 more source

Decompressive Craniectomy and Traumatic Brain Injury: A Review [PDF]

open access: yesBulletin of Emergency and Trauma, 2013
Intracranial hypertension is the largest cause of death in young patients with severe traumatic brain injury. Decompressive craniectomy is part of the second level measures for the management of increased intracranial pressure refractory to medical ...
Hernando Alvis-Miranda   +2 more
doaj  

In edition: artists’ multiples in an academic library [PDF]

open access: yes, 2004
The artist's multiple is difficult to define, but could be described as an original artwork produced in an edition of two or more. At Chelsea College of Art and Design, the artists' multiples collection was developed to give students first-hand ...
Kaplish, Lalita, Lawes, Elizabeth
core  

Oral KDS2010, a Monoamine Oxidase‐B (MAO‐B) Inhibitor, Slows the Deterioration of Motor Coordination in Genetic SCA1 Models by Inhibiting Astrocytic MAO‐B‐Mediated Inflammation

open access: yesJournal of Neurochemistry, Volume 169, Issue 12, December 2025.
Astrocytes play a critical role in neurodegenerative disease pathology by modulating inflammatory responses and clearing toxic protein aggregates. In this study, we evaluated the therapeutic potential of KDS2010, a reversible and selective MAO‐B inhibitor, in a mouse model of spinocerebellar ataxia type 1 (SCA1).
Dong Ho Woo   +7 more
wiley   +1 more source

Changes in Health Risks, Daily Activities, and Antipsychotic Use After Humanitude Care for People With Dementia: A Retrospective Study

open access: yesJournal of Clinical Nursing, Volume 34, Issue 12, Page 5350-5357, December 2025.
ABSTRACT Aim This study examined changes in health risk, daily activities and antipsychotic use after receiving Humanitude care for people with dementia. Design Retrospective study design. Methods A total of 67 people with dementia were admitted to two municipal nursing hospitals and were receiving Humanitude care.
Sungjun Kim   +3 more
wiley   +1 more source

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