Results 91 to 100 of about 16,002 (187)

Triethylammonium 1,3-dimethyl-5-(2,4,6-trinitrophenyl)barbiturate

open access: yesActa Crystallographica Section E, 2012
In the title molecular salt [systematic name: triethylammonium 1,3-dimethyl-2,6-dioxo-5-(2,4,6-trinitrophenyl)-1,2,3,6-tetrahydropyrimidin-4-olate], C6H16N+·C12H8N5O9−, the dihedral angle between the aromatic rings in the anion is 46 ...
Kulandaiya Rajamani   +1 more
doaj   +1 more source

Health, Social and Recidivism Outcomes Among People Who Have Been Incarcerated in New South Wales, Australia: Study Protocol and Cohort Profile for the Prison Outcomes STudy (POST)

open access: yesDrug and Alcohol Review, Volume 45, Issue 5, July 2026.
ABSTRACT Introduction We have been funded to examine post‐incarceration health and social outcomes for all people incarcerated in New South Wales, Australia, 2000–2022; assess treatment and services for drug dependence and serious mental illness; and project the impact of expanding intervention coverage. We will use a linked cohort, the Prison Outcomes
Louisa Degenhardt   +19 more
wiley   +1 more source

Coma Blisters

open access: yesCase Reports in Dermatology, 2009
Coma blisters are lesions that occur in the setting of a variety of neurological diseases. Although most commonly associated with barbiturate overdose, they can be seen in the setting of coma due to other etiologies.
Joana Rocha   +4 more
doaj   +1 more source

Suzetrigine as a novel treatment for headache disorders: A case series

open access: yesHeadache: The Journal of Head and Face Pain, Volume 66, Issue 7, Page 1644-1649, July/August 2026.
Abstract Suzetrigine is a selective voltage‐gated sodium channel blocker that was recently approved by the US Food and Drug Administration for the treatment of acute pain. We retrospectively evaluated the efficacy and tolerability of suzetrigine for the treatment of different headache disorders in patients refractory to standard treatments in an ...
Molly Fensterwald   +15 more
wiley   +1 more source

Interaction of Barbiturate Analogs with the Torpedo californica Nicotinic Acetylcholine Receptor Ion Channel [PDF]

open access: yes, 2001
Barbiturate-induced anesthesia is a complex mechanism that probably involves several ligand-gated ion channel superfami-lies. One of these superfamilies includes the archetypical nic-otinic acetylcholine receptor (nAChR), in which barbiturates act as ...
McCardy, Elizabeth A.   +7 more
core  

Electromechanical modelling and simulation of human‐induced pluripotent stem cell‐derived cardiomyocytes predict drug‐induced contractility effects

open access: yesThe Journal of Physiology, Volume 604, Issue 13, Page 5629-5662, 1 July 2026.
Abstract figure legend A study described in this paper describes a new tool for hiPSC‐CM electromechanical behaviour simulations using mathematical modelling. The model enables in silico assays making drug testing quick, comprehensive and accurate. New hiPSC‐CM models can be used as a platform to integrate in vitro and in silico findings.
Milda Folkmanaite   +9 more
wiley   +1 more source

Some drug effects influencing barbiturate facilitation of water ingestion

open access: yes, 1959
Pentobarbital was studied in combination with chlorpromazine and a stimulant barbiturate (5 ethyl, 5, 1, 3, dimethyl-2-butenyl barbituric acid) with respect to water intake in the rat. Each depressed water intake when administered alone.
H. Schmidt, S. J. Moak
core   +1 more source

Triethylammonium 2,4-dinitrophenylbarbiturate

open access: yesActa Crystallographica Section E, 2009
In the title molecular salt [systematic name: triethylammonium 5-(2,4-dinitrophenyl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-olate], C6H16N+·C10H5N4O7−, the cation and anion are linked by an N—H...O hydrogen bond.
Doraisamyraja Kalaivani   +1 more
doaj   +1 more source

Isotellurourea‐Catalyzed Enantioselective (4+2)‐Heterocycloadditions of But‐2‐ynoates and Michael Acceptors

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 24, 23 June 2026.
Isotelluroureas allow for the use of alkynoates for asymmetric (4+2)‐heterocycloadditions with different Michael acceptors. Alk‐2‐ynoates are readily available starting materials which, in principle, can be utilized for cycloadditions in analogy to structurally similar allenoates.
Anna Scheucher, Mario Waser
wiley   +1 more source

Evaluation of EMIT tox benzodiazepine and barbiturate assays on the Vitalab Viva analyser and FPIA on the Abbott ADx analyser

open access: yes, 2000
peer reviewedWe evaluated the performance of the Emit® tox benzodiazepine and barbiturate assays (Dade Behring) and fluorescence polarisation immunoassay (FPIA) (Abbott) for use with serum determinations in preliminary therapeutic drug monitoring or ...
Charlier, Corinne, Plomteux, Guy
core   +1 more source

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