Results 81 to 90 of about 16,002 (187)

Protocol‐Based Management of Medication Confounders in Brain Death Determination: A Multi‐Institutional Review

open access: yesJACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, Volume 9, Issue 7, July 2026.
ABSTRACT Background Determination of death by neurologic criteria (DNC) relies on clinical examination, provided no confounding conditions affect reliability. Current guidelines require patients to be free of confounders before neurologic testing but do not specify how these confounders should be assessed or managed.
Alexander Nixon   +7 more
wiley   +1 more source

Barbiturate poisoning

open access: yes, 2016
Wstęp: Barbiturany to grupa leków o działaniu nasennym. Zatrucia nimi mogą być zarówno przewlekłe, jak i ostre. W zależności od dawki i przyjętego preparatu pierwsze objawy mogą wystąpić już po kilku minutach.
Ślęzak, Daniel   +3 more
core   +1 more source

Epilepsy: Epidemiology, Molecular Pathogenesis, and Clinical Management

open access: yesMedComm, Volume 7, Issue 7, July 2026.
Epilepsy is a heterogeneous and chronically evolving brain network disorder. This review integrates epidemiological burden, psychiatric comorbidities, and cyclic seizure patterns with multiscale pathogenic mechanisms, including ion‐channel dysfunction, synaptic transmission defects, neuroinflammation, metabolic and mitochondrial dysfunction, and ...
Jian Liu   +8 more
wiley   +1 more source

ETHANOL AND BARBITURATE CONCENTRATIONS IN POSTMORTEM TISSUES.

open access: yes, 1972
ETHANOL AND BARBITURATE CONCENTRATIONS IN POSTMORTEM ...
GEORGE NICK. CHRISTOPOULOS (7983656)
core  

Brain pH in Focal Cerebral Ischemia and the Protective Effects of Barbiturate Anesthesia

open access: yes, 1983
Intracellular brain pH was measured with a lipid-soluble, pH-sensitive fluorescent indicator in 16 squirrel monkeys. Eight of these were under halothane anesthesia and eight under barbiturate anesthesia.
Thoralf M. Sundt, Robert E. Anderson
core   +1 more source

A Historical Drug or a Current Problem? Determination of Methaqualone and Its Analogs in Biological Material via UHPLC-QqQ-MS/MS

open access: yesProceedings
Introduction: Methaqualone was introduced to the market in the 1960s as a sedative–hypnotic drug, intended as an alternative to compounds in the barbiturate group [...]
Kaja Tusiewicz   +2 more
doaj   +1 more source

State-Dependent Modulation of Slow Wave Motifs towards Awakening

open access: yesFrontiers in Cellular Neuroscience, 2017
Slow cortical waves that propagate across the cerebral cortex forming large-scale spatiotemporal propagation patterns are a hallmark of non-REM sleep and anesthesia, but also occur during resting wakefulness.
Thomas Knöpfel   +6 more
doaj   +1 more source

Preclinical models for evaluating psychedelics in the treatment of major depressive disorder

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 14, Page 3970-3991, July 2026.
Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander   +5 more
wiley   +1 more source

The effects of drugs on barbiturate withdrawal convulsions in the rat

open access: yes, 1970
The effects of drugs on barbitone withdrawal convulsions in rats have been examined. Morphine and mebanazine had no effect on audiogenically induced barbiturate withdrawal seizures.
P R E Norton
core   +1 more source

Artificial receptor-attached amphiphilic copolymer for barbiturate binding in aqueous media

open access: yes, 2004
A water-soluble self-associating amphiphilic copolymer was employed to provide a microenvironment for the solvation of a hydrogen-bonding barbiturate artificial receptor, to facilitate molecular recognition in water.
Zeinalipour-Yazdi, C.   +2 more
core   +2 more sources

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