Results 61 to 70 of about 13,944 (198)
Clonidine-Activation of Epileptic Foci
The effects of clonidine, an adrenergic a2 agonist hypotensive agent, and methoxital, a short-acting barbiturate anesthetic, on epileptiform discharges detected by presurgical magnetoencephalography (MEG) were investigated in 14 patients with medically ...
J Gordon Millichap
doaj +1 more source
ABSTRACT Background Complex regional pain syndrome type 1 (CRPS1) is a disabling pain syndrome whose treatment remains challenging. Mesotherapy is a therapeutic method involving the injection of low doses of active substances through the skin. No studies assessed mesotherapy in CRPS1 patients.
Philippe Lafuma +12 more
wiley +1 more source
Introduction: Methaqualone was introduced to the market in the 1960s as a sedative–hypnotic drug, intended as an alternative to compounds in the barbiturate group [...]
Kaja Tusiewicz +2 more
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State-Dependent Modulation of Slow Wave Motifs towards Awakening
Slow cortical waves that propagate across the cerebral cortex forming large-scale spatiotemporal propagation patterns are a hallmark of non-REM sleep and anesthesia, but also occur during resting wakefulness.
Thomas Knöpfel +6 more
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A MgBr2‐catalyzed (3+2) cycloaddition between N‐thioacyl amidines and donor–acceptor cyclopropanes provides rapid access to 2‐amidino‐thiolanes in good yields and with high diastereoselectivities. The method displays broad substrate scope and offers an efficient route to sulfur‐containing amidine scaffolds of potential biological relevance.
Laurine Tual +4 more
wiley +1 more source
Triethylammonium 1,3-dimethyl-5-(2,4,6-trinitrophenyl)barbiturate
In the title molecular salt [systematic name: triethylammonium 1,3-dimethyl-2,6-dioxo-5-(2,4,6-trinitrophenyl)-1,2,3,6-tetrahydropyrimidin-4-olate], C6H16N+·C12H8N5O9−, the dihedral angle between the aromatic rings in the anion is 46 ...
Kulandaiya Rajamani +1 more
doaj +1 more source
Recurrent Hypothermia and Autonomic Dysfunction Secondary to Shapiro Syndrome
ABSTRACT A 44‐year‐old man presented with recurrent hypothermia, diaphoresis and hypertension. Extensive investigation for infectious, inflammatory, metabolic and endocrine aetiologies was negative. MR scan of the brain demonstrated no lesions but revealed callosal dysgenesis, consistent with Shapiro syndrome.
Naveen Kumar +3 more
wiley +1 more source
Coma blisters are lesions that occur in the setting of a variety of neurological diseases. Although most commonly associated with barbiturate overdose, they can be seen in the setting of coma due to other etiologies.
Joana Rocha +4 more
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Identification of Barbiturates [PDF]
IN Great Britain the most common poisons at the present time are the 5 : 5′ disubstituted barbiturates. The longer-acting barbiturates, barbitone and phenobarbitone, can accumulate in the body when administered in relatively low therapeutic dosage, and concentrations of these drugs in the blood of about 5 mgm./100 ml. do not necessarily imply poisoning.
openaire +2 more sources
An enantioselective Mannich reaction using barbituric acids as nucleophiles provides access to chiral heterocycles bearing quaternary stereocenters. The transformation is catalyzed by a bifunctional thiourea with high selectivity. An immobilized catalyst enables recycling and application under continuous‐flow conditions, offering an efficient and ...
Rodrigo Sánchez‐Molpeceres +4 more
wiley +1 more source

