Results 41 to 50 of about 13,944 (198)

Brain reward function in young people with cannabis use disorder: A functional magnetic resonance imaging study

Addiction, EarlyView.
Abstract Background and Aims Cannabis use disorder (CUD) affects ~50 million people globally. Neuroscientific theories suggest that a blunted neural response to non‐drug rewards is a hallmark of substance use disorders; however, this remains untested in CUD. The current study tested whether brain reward system responses to the anticipation and feedback
Martine Skumlien, Lisa‐Marie Greenwood, Arush Honnedevasthana Arun, Isabella Goodwin, Anastasia Paloubis, Tribikram Thapa Rana, Marianna Quinones Valera, Eugene McTavish, Gabrielle Abbott, Suraya Dunsford, Antonio Verdejo‐Garcia, Jessica Ramamurthy, Mark M. Schira, Nadia Solowij, Chao Suo, Valentina Lorenzetti   +15 more
wiley   +1 more source

Trimethylammonium 5-(2,4-dinitrophenyl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-olate 0.125-hydrate

Acta Crystallographica Section E, 2013
The asymmetric unit of the title salt C3H10N+·C10H5N4O7−·0.125H2O [trivial name: trimethylammonium 5-(2,4-dinitrophenyl)barbiturate 0.125-hydrate], contains two independent cations, two independent anions and a 0.25-occupancy solvent ...
Govindan Mangaiyarkarasi, Doraisamyraja Kalaivani   +1 more
doaj   +1 more source

Intermittent cocaine use patterns, not total intake, predict cue‐induced drug seeking in rats

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Cocaine‐associated cues trigger relapse to drug use in humans and animal models. In rats, long daily cocaine access (4–6 vs. 1–2 h) increases drug self‐administration and cue‐induced cocaine seeking, suggesting that greater intake promotes relapse.
Amélie Mainville‐Berthiaume, Hajer Algallal, Salomé Dupuis, Sema Abu Shamleh, Coralie Godbout, Vincent Jacquemet, Anne‐Noël Samaha   +6 more
wiley   +1 more source

N,N-Diethylanilinium 5-(2,4-dinitrophenyl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-olate

Acta Crystallographica Section E, 2013
The asymmetric unit of the title molecular salt, C10H16N+·C10H5N4O7− (trivial name: N,N-diethylanilinium 2,4-dinitrophenylbarbiturate), comprises two anion–cation units.
Govindan Mangaiyarkarasi, Doraisamyraja Kalaivani   +1 more
doaj   +1 more source

Is Hypercortisolism Treatable? Which Patients Should Be Treated and How—A Practical Guide for Clinicians

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim To provide a practical guide on when to suspect endogenous hypercortisolism, how to use the overnight 1‐mg dexamethasone suppression test (DST) for targeted case‐finding, and which patients are most likely to benefit from treatment.
Juan Pablo Frias
wiley   +1 more source

Drugs analysis using latex agglutination tests

Тонкие химические технологии, 2011
The method of latex agglutination was used to develop express diagnostics of the most extended groups of drugs (opiates, cannabinoides and barbiturates).
N. М. Solodukhina, Т. V. Abramenko, М. А. Myagkova, I. А. Gritskova   +3 more
doaj  

Step-down infusion of barbiturate improves neurofunction in a new rat model of rebleeding subarachnoid hemorrhage

Brain Hemorrhages
Objective: Rebleeding from a ruptured aneurysm is a risk factor for fatal prognosis in subarachnoid hemorrhage (SAH). A novel barbiturate treatment, step-down infusion of barbiturate (sd-B), was previously developed; it showed beneficial effects on ...
Sosho Kajiwara, Yu Hasegawa, Kana Fujimori, Motohiro Morioka   +3 more
doaj   +1 more source

A patient‐centered conceptual model and measurement framework for migraine experience developed by the Migraine Clinical Outcome Assessment System

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective To develop a comprehensive, evidence‐based, patient‐centered conceptual model of migraine and to derive a measurement framework for the development or selection of clinical outcome assessments used in clinical trials of treatments for migraine.
Rikki Mangrum, Alexandra L. Bryant, Carrie R. Houts, James S. McGinley, Dawn C. Buse, Richard B. Lipton, R. J. Wirth   +6 more
wiley   +1 more source

Beyond the Law: A Qualitative Socio‐Ecological Study of Substance Use Treatment Barriers and Adaptations in Ghana

Journal of Psychiatric and Mental Health Nursing, EarlyView.
ABSTRACT Background Ghana's response to substance use has long been dominated by criminalisation, yet limited research has examined how this policy environment shapes addiction treatment delivery. This study explored the perspectives of mental health nurses providing care to people who use drugs (PWUDs) using a socio‐ecological framework.
Evans F. Kyei, Dorothy Wilson, Grace K. Kyei, Rockson Ansong, Mercy N. Mumba   +4 more
wiley   +1 more source

5-[1-(1,3-Dimethyl-2,4,6-trioxohexahydropyrimidin-5-yl)-2-oxopropyl]-1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione

Acta Crystallographica Section E, 2013
The title compound, C15H18N4O7, is a product of the substitution reaction of 5,5-dibromo-1,3-dimethylbarbituric acid with sodium sulfide in aqueous acetone.
Manfred Steimann, Kamal Sweidan
doaj   +1 more source