Results 31 to 40 of about 17,479 (167)
Animal stroke models and outcome evaluation: A review
Animal Models and Experimental Medicine, EarlyView.Rodents are the preeminent stroke model species. Large animal models exist too, but are poorly standardized. Ischemic and hemorrhagic experimental models are available, with the intraluminal filament model being predominant. Outcomes are evaluated via quantifying subjects' sensorimotor impairment, cognitive memory faculties, degree of cellular ...
Solsa Cariba +2 more
wiley +1 more source
N,N-Diethylanilinium 2,4-dioxo-5-(2,4,6-trinitrophenyl)-1,2,3,4-tetrahydropyrimidin-6-olate
Acta Crystallographica Section E, 2011 In the crystal structure of the title molecular salt, C10H16N+·C10H4N5O9−, the components are linked through a N—H...O hydrogen bonds. R22(8) ring motifs are formed between inversion-related barbiturate residues.
Manickam Buvaneswari +1 more
doaj +1 more source
5,5-Dihydroxybarbituric acid 1,4-dioxane hemisolvate
Acta Crystallographica Section E, 2010 The asymmetric unit of the title compound,, C4H4N2O5·0.5C4H8O2, contains one molecule of 5,5-dihydroxybarbituric acid with a nearly planar barbiturate ring and half a molecule of 1,4-dioxane.
Thomas Gelbrich +2 more
doaj +1 more source
The Anatomical Record, EarlyView.Abstract The organization and function of reptilian excurrent ducts remain poorly characterized, particularly in Neotropical snakes. We provide the first integrative morphological, histochemical, immunohistochemical, and ultrastructural analysis of the proximal post‐testicular ducts of Crotalus durissus across reproductive stages.
Flávia Cappuccio de Resende +9 more
wiley +1 more source
Acta Crystallographica Section E, 2011 In the title molecular salt, C6H16NO+·C10H4N5O9−·2H2O, which crystallizes as a dihydrate, O—H...O hydrogen bonds link the barbiturate anion, the ethanaminium cation and the water molecules of crystallization.
Manickam Buvaneswari +1 more
doaj +1 more source
ChemElectroChem, 2023 A highly efficient, fast, catalyst‐free, and atom economical method was developed for the synthesis of 5‐benzylidenebarbiturates. Thus, reacting barbituric acid and aldehydes in water as a green solvent under electrochemical conditions afforded the ...
Dr. Yara S. El‐Dash +3 more
doaj +1 more source
Zuranolone: A case study in (regulatory) rush to judgement?
British Journal of Clinical Pharmacology, EarlyView.Abstract Sage, in collaboration with Biogen, submitted a new drug approval for zuranolone for postpartum depression (PPD) and major depressive disorder (MDD) in December 2022. In August 2023, the US Food and Drug Administration granted approval for PPD but denied approval for MDD.
Lisa Cosgrove +4 more
wiley +1 more source
Infrared and Thermal Analysis of Vanadyl(II) Barbiturate Complex [PDF]
, 2009 An usual method for the preparation of vanadyl(II) barbiturate complex was performed under the chemical reaction of vanadyl(II) sulfate with barbituric acid (H2L) and formulated as: [VO(HL)2].2H2O.
Refat, Moamen S. +3 more
core +1 more source
Trimethylammonium 2,6-dioxo-5-(2,4,6-trinitrophenyl)-1,2,3,6-tetrahydropyrimidin-4-olate
Acta Crystallographica Section E, 2012 In the title barbiturate salt (trivial name: trimethylammonium 2,4,6-trinitrophenylbarbiturate), C3H10N+·C10H4N5O9−, the asymmetric unit contains two sets of anion–cation moieties.
D. Kalaivani +2 more
doaj +1 more source
CYP3A5 genetic variability influences sildenafil and metabolite in pulmonary hypertension
British Journal of Clinical Pharmacology, EarlyView.Aim Interindividual variability in sildenafil response among pulmonary hypertension patients (PH) may be influenced by CYP3A5 polymorphisms. CYP3A5*3 allele reduces CYP3A5 activity and affects sildenafil metabolism. This study investigated the associations between CYP3A5 genotype and plasma concentrations of sildenafil and N‐desmethyl sildenafil, as ...
Pranisa Wongwien +7 more
wiley +1 more source