Results 11 to 20 of about 13,944 (198)

Efficacy of Step-down Infusion Method of a Novel Barbiturate Therapy for Severe Subarachnoid Hemorrhage with Intracerebral Hematoma [PDF]

Neurologia Medico-Chirurgica
Currently, there is no effective treatment for elevated intracranial pressure in the acute phase of subarachnoid hemorrhage. Recently, we developed “step-down infusion of barbiturate,” a therapeutic strategy for severe traumatic brain injury, which ...
Jin KIKUCHI, Yu HASEGAWA, Sosho KAJIWARA, Yusuke OTSU, Tetsuya NEGOTO, Kimihiko ORITO, Osamu TAKASU, Masaru HIROHATA, Motohiro MORIOKA   +8 more
doaj   +2 more sources

2-Amino-5-chloropyridin-1-ium barbiturate dihydrate [PDF]

IUCrData
In the title hydrated salt, C5H6ClN2+·C4H3N2O3−·2H2O, the asymmetric unit contains two cations, two anions and four water molecules of crystallization. In the extended structure, the barbiturate (2,4,6-trioxo-1,3-diazinan-5-ide) anions form a wave-like ...
Thankappan Ramalakshmi Anantheeswary, Sundaramoorthy Gomathi, Jeyaraman Selvaraj Nirmalram, Franc Perdih   +3 more
doaj   +2 more sources

Sodium Amytal – No Longer Prescribed, but Still Relevant (And Dangerous!) [PDF]

BJPsych Open
Aims: Sodium amytal is a barbiturate medication, first synthesised in Germany in the 1920s to treat anxiety and sleep disorders; as well as being used as an anaesthetic.
Conor Brown
doaj   +2 more sources

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Novel Barbiturate-Nitrate Compounds Inhibit the Upregulation of Matrix Metalloproteinase-9 Gene Expression in Intestinal Inflammation through a cGMP-Mediated Pathway

Biomolecules, 2020
Matrix metalloproteinase-9 is upregulated in inflammatory bowel disease. Barbiturate nitrate hybrid compounds have been designed to inhibit MMP secretion and enzyme activity.
Shane O’Sullivan, Jun Wang, Marek W. Radomski, John F. Gilmer, Carlos Medina   +4 more
doaj   +1 more source

Quantitative burst suppression on serial intermittent EEG in refractory status epilepticus

Clinical Neurophysiology Practice, 2021
Objectives: In refractory status epilepticus (RSE), the optimal degree of suppression (EEG burst suppression or merely suppressing seizures) remains unknown.
Joseph Peedicail, Neil Mehdiratta, Shenghua Zhu, Paulina Nedjadrasul, Marcus C. Ng   +4 more
doaj   +1 more source

Crystal structure and biological evaluation of 4-methylmorpholin-4-ium 1,3-dimethyl-2,6-dioxo-5-(2,4,6-trinitrophenyl)-1,2,3,6-tetrahydropyrimidin-4-olate

Acta Crystallographica Section E: Crystallographic Communications, 2015
The title molecular salt, C5H12NO+·C12H8N5O9− [common name: 4-methylmorpholin-4-ium 1,3-dimethyl-5-(2,4,6-trinitrophenyl)barbiturate], possesses noticeable anticonvulsant and hypnotic activity.
Jeganathan Gomathi, Doraisamyraja Kalaivani   +1 more
doaj   +1 more source

Barbiturat dan Obat Pelumpuh Otot: Masih Bermanfaat untuk Menangani Hipertensi Intrakranial?

Jurnal Neuroanestesi Indonesia, 2013
Hipertensi intrakranial dapat menyebabkan cedera otak sekunder dan meningkatkan morbiditas serta mortalitas. Untuk mempertahankan tekanan intrakranial agar senantiasa dalam batas normal, maka cairan serebrospinal dan darah mempunyai kemampuan untuk ...
M. Sofyan Harahap
doaj   +1 more source

Delayed post−hypoxic leukoencephalopathy following barbiturate overdose: A case report

Journal of Acute Disease, 2022
Rationale: Delayed post-hypoxic leukoencephalopathy (DPHL) is usually an overlooked condition, which arises as a result of a multitude of reversible and irreversible conditions.
Arshi Syal, Samiksha Gupta, Monica Gupta, Gautam Jesrani, Yajur Arya   +4 more
doaj   +1 more source

Barbiturate AEDS, EEG and Cognitive Performance

Pediatric Neurology Briefs, 1997
Neuropsychological performance and quantitative EEGs were studied in 11 epileptic children, aged 7 to 14 years, both during treatment and without phenobarbital and mephobarbital, and in comparison to 13 matched controls, at Tulane University Medical ...
J Gordon Millichap
doaj   +1 more source