Results 11 to 20 of about 17,479 (167)

Barbiturate-refractory epilepsy: safe schedule for therapeutic substitution

open access: yesArquivos de Neuro-Psiquiatria, 1986
Barbiturates are considered first line antiepileptic drugs in third world countries due to traditional and economic reasons. This prospective uncontrolled study of 52 patients aged 15 to 64 years (mean 24) demonstrates that patients who become refractory
Ana Maria Gorz   +2 more
doaj   +2 more sources

Towards interlocked structures based on H-bonded barbiturate complexes [PDF]

open access: yes, 2010
Despite the privileged position of Hamilton’s barbiturate binding system in supramolecular chemistry, this motif has never been used in generating interlocked structures, such as rotaxanes or catenanes.
Rocher, Mathias
core   +7 more sources

ETHANOL AND BARBITURATE CONCENTRATIONS IN POSTMORTEM TISSUES.

open access: yes, 1972
ETHANOL AND BARBITURATE CONCENTRATIONS IN POSTMORTEM ...
GEORGE NICK. CHRISTOPOULOS (7983656)
core   +6 more sources

Barbiturate-related hospitalisations, drug treatment episodes, and deaths in Australia, 2000-2018.

open access: yes, 2022
OBJECTIVES: To determine the characteristics and population rates of barbiturate-related hospitalisations, treatment episodes, and deaths in Australia, 2000-2018.
Chrzanowska, Agata   +4 more
core   +1 more source

Crystal structure of 4-aminopyridinium 5-(5-chloro-2,4-dinitrophenyl)-1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-olate hemihydrate

open access: yesActa Crystallographica Section E, 2014
The title molecular salt, C5H7N2+·C12H8ClN4O7−·0.5H2O, crystallizes as a hemihydrate. The two rings in the barbiturate anion are not coplanar but make a dihedral angle of 43.17 (16)°. The two nitro groups deviate from the ring to which they are attached;
Manickkam Vaduganathan   +1 more
doaj   +1 more source

Butallylonal 1,4-dioxane hemisolvate

open access: yesActa Crystallographica Section E, 2010
The asymmetric unit of the title compound [systematic name: 5-(1-bromoprop-2-en-1-yl)-5-sec-butylpyrimidine-2,4,6-trione 1,4-dioxane hemisolvate], C11H15BrN2O3·0.5C4H8O2, contains one half-molecule of 1,4-dioxane and one molecule of butallylonal,
Ulrich J. Griesser   +2 more
doaj   +1 more source

Unexpected epileptogenic effect of lethal doses of pentobarbital: a case report [PDF]

open access: yesJournal of Neurocritical Care, 2023
Background Barbiturate poisoning is rare but potentially fatal. Case Report We reported a case of barbiturate poisoning in a 28-year-old woman who recovered from lethal pentobarbital deliberate self-poisoning.
Amélie Giudicelli-Bailly   +5 more
doaj   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

open access: yes, 2022
Hepatology, EarlyView.
Robert J. Fontana   +6 more
wiley   +1 more source

Crystal structure of the α-racemate of methohexital

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2015
Molecules of the title compound, C14H18N2O3 [systematic name: 5-allyl-5-(hex-3-yn-2-yl)-1-methylpyrimidine-2,4,6(1H,3H,5H)-trione in the (RbSh)/(SbRh) racemic form], are connected by mutual N—H...O=C hydrogen bonds in which the carbonyl group at the 2 ...
Thomas Gelbrich, Ulrich J. Griesser
doaj   +1 more source

Novel Barbiturate-Nitrate Compounds Inhibit the Upregulation of Matrix Metalloproteinase-9 Gene Expression in Intestinal Inflammation through a cGMP-Mediated Pathway

open access: yesBiomolecules, 2020
Matrix metalloproteinase-9 is upregulated in inflammatory bowel disease. Barbiturate nitrate hybrid compounds have been designed to inhibit MMP secretion and enzyme activity.
Shane O’Sullivan   +4 more
doaj   +1 more source

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