Results 11 to 20 of about 16,002 (187)

Barbiturate-refractory epilepsy: safe schedule for therapeutic substitution

open access: yesArquivos de Neuro-Psiquiatria, 1986
Barbiturates are considered first line antiepileptic drugs in third world countries due to traditional and economic reasons. This prospective uncontrolled study of 52 patients aged 15 to 64 years (mean 24) demonstrates that patients who become refractory
Ana Maria Gorz   +2 more
doaj   +2 more sources

An Interesting Case of Barbiturate Automatism and Review of Literature [PDF]

open access: yesCase Reports in Neurological Medicine, 2013
A 48 year old man with a diagnosis of HIV infection since 1993, on highly active anti-retro viral therapy (HAART) with stable CD4 count and undetectable viral load for years and seizure disorder presented with recurrent drowsiness. His seizures were well
Sankalp Gokhale, Ciro Ramos-Estebanez
doaj   +2 more sources

Barbiturate-related hospitalisations, drug treatment episodes, and deaths in Australia, 2000-2018.

open access: yes, 2022
OBJECTIVES: To determine the characteristics and population rates of barbiturate-related hospitalisations, treatment episodes, and deaths in Australia, 2000-2018.
Chrzanowska, Agata   +4 more
core   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

open access: yes, 2022
Hepatology, EarlyView.
Robert J. Fontana   +6 more
wiley   +1 more source

Butallylonal 1,4-dioxane hemisolvate

open access: yesActa Crystallographica Section E, 2010
The asymmetric unit of the title compound [systematic name: 5-(1-bromoprop-2-en-1-yl)-5-sec-butylpyrimidine-2,4,6-trione 1,4-dioxane hemisolvate], C11H15BrN2O3·0.5C4H8O2, contains one half-molecule of 1,4-dioxane and one molecule of butallylonal,
Ulrich J. Griesser   +2 more
doaj   +1 more source

Unexpected epileptogenic effect of lethal doses of pentobarbital: a case report [PDF]

open access: yesJournal of Neurocritical Care, 2023
Background Barbiturate poisoning is rare but potentially fatal. Case Report We reported a case of barbiturate poisoning in a 28-year-old woman who recovered from lethal pentobarbital deliberate self-poisoning.
Amélie Giudicelli-Bailly   +5 more
doaj   +1 more source

Crystal structure of the α-racemate of methohexital

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2015
Molecules of the title compound, C14H18N2O3 [systematic name: 5-allyl-5-(hex-3-yn-2-yl)-1-methylpyrimidine-2,4,6(1H,3H,5H)-trione in the (RbSh)/(SbRh) racemic form], are connected by mutual N—H...O=C hydrogen bonds in which the carbonyl group at the 2 ...
Thomas Gelbrich, Ulrich J. Griesser
doaj   +1 more source

Novel Barbiturate-Nitrate Compounds Inhibit the Upregulation of Matrix Metalloproteinase-9 Gene Expression in Intestinal Inflammation through a cGMP-Mediated Pathway

open access: yesBiomolecules, 2020
Matrix metalloproteinase-9 is upregulated in inflammatory bowel disease. Barbiturate nitrate hybrid compounds have been designed to inhibit MMP secretion and enzyme activity.
Shane O’Sullivan   +4 more
doaj   +1 more source

Diastereoselective and Enantioselective Synthesis of Barbiturate-Fused Spirotetrahydroquinolines via Chiral Palladium(0)/Ligand Complex Catalyzed [4 + 2] Cycloaddition of Vinyl Benzoxazinanones with Barbiturate-Based Olefins

open access: yes, 2018
Under the catalysis of chiral palladium(0)/ligand complex, the [4 + 2] cycloaddition between vinyl benzoxazinanones and barbiturate-based olefins proceeded readily and provided barbiturate-fused spirotetrahydroquinolines in up to 96% chemical yield with ...
Li-Ru Wang (5559320)   +6 more
core   +2 more sources

Quantitative burst suppression on serial intermittent EEG in refractory status epilepticus

open access: yesClinical Neurophysiology Practice, 2021
Objectives: In refractory status epilepticus (RSE), the optimal degree of suppression (EEG burst suppression or merely suppressing seizures) remains unknown.
Joseph Peedicail   +4 more
doaj   +1 more source

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