Results 71 to 80 of about 17,479 (167)

Distinctive neurophysiological correlates of sound onset and offset perception in humans

The Journal of Physiology, EarlyView.
Abstract figure legend Electroencephalography (EEG) recordings were obtained from participants listening to successive pairs of 1‐2 s noises in a silent background (Study 1) or successive pairs 1‐2 s silent gaps in a noise background (Study 2). Participants heard the same stimuli in the context of either a duration discrimination task (identifying ...
Fatima Ali, Gabriela Bury, Adèle Simon, Jennifer F. Linden   +3 more
wiley   +1 more source

Potentiometric Membrane Sensors for the Selective Determination of Memantine Hydrochloride in Pharmaceutical Preparations

International Journal of Electrochemical Science, 2012
Three potentiometric sensors responsive to Memantine HCl (MEM) drug are described, characterized, compared and used for drug assessment. The sensors are based on the use of the ion-association complex of (MEM) cation with Flavianate (FA), 5-Nitro ...
Rasha M. El Nashar, Aliaa S.M. El-Tantawy, Saad S.M. Hassan   +2 more
doaj   +1 more source

Integrated Phytochemical Characterisation, Pharmacological Evaluation and Computational Investigation of Acampe papillosa Stem Extract

Analytical Science Advances, Volume 7, Issue 2, December 2026.
The pharmacological potential of the methanolic stem extract of Acampe papillosa is evaluated using in vivo and in silico approaches. The extract demonstrates significant anxiolytic, sedative, anti‐inflammatory, and antipyretic activities in experimental models, while molecular docking supports the observed biological effects through favorable ...
Qurratul Ain Sadia, Sadia Tamanna Tamim, Faruq Mohammed Tashriq, Nasir Uddin, Fatematus Zhohara Alam Hima, Ulfat Sobha Surat, Mily Khastagir, Muhammad Abdul Jalil, Md. Hossain Rasel, Arman Ullah Rafi, S. M. Moazzem Hossen   +10 more
wiley   +1 more source

Graphene oxide enhances SBA-15 ability towards preconcentration as well as determination of barbiturate drug in real samples

Kuwait Journal of Science, 2019
In this study, a simple, sensitive, and high performance method was employed to extract and preconcentration of trace amount of sodium barbiturate drug by using mesoporous silica (SBA-15) modified by graphene oxide (GO).
Ali Shokuhi Rad, Ali Mirabi, Sadaf Ahmadizadeh   +2 more
doaj  

Clonidine-Activation of Epileptic Foci

Pediatric Neurology Briefs, 1998
The effects of clonidine, an adrenergic a2 agonist hypotensive agent, and methoxital, a short-acting barbiturate anesthetic, on epileptiform discharges detected by presurgical magnetoencephalography (MEG) were investigated in 14 patients with medically ...
J Gordon Millichap
doaj   +1 more source

Acute Pain During Intensive Care: Prevalence, Predisposing Factors and Pain Trajectories. A Prospective Multicenter Observational Study

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 9, October 2026.
ABSTRACT Background A considerable proportion of patients in the intensive care unit (ICU) experience pain. The objective of this prospective observational cohort study was to investigate the prevalence of pain, factors associated with pain and pain trajectories in ICU patients.
Aleksandra E. Wlodarczyk‐Abou Elseoud, Maija‐Liisa Kalliomäki, Otto Mäkinen, Annika Laukkanen, Minna Bäcklund, Mitja Lääperi, Katri Hamunen, Anna‐Maria Kuivalainen   +7 more
wiley   +1 more source

Intermittent cocaine use patterns, not total intake, predict cue‐induced drug seeking in rats

British Journal of Pharmacology, Volume 183, Issue 20, Page 6094-6112, October 2026.
Abstract Background and Purpose Cocaine‐associated cues trigger relapse to drug use in humans and animal models. In rats, long daily cocaine access (4–6 vs. 1–2 h) increases drug self‐administration and cue‐induced cocaine seeking, suggesting that greater intake promotes relapse.
Amélie Mainville‐Berthiaume, Hajer Algallal, Salomé Dupuis, Sema Abu Shamleh, Coralie Godbout, Vincent Jacquemet, Anne‐Noël Samaha   +6 more
wiley   +1 more source

A Historical Drug or a Current Problem? Determination of Methaqualone and Its Analogs in Biological Material via UHPLC-QqQ-MS/MS

Proceedings
Introduction: Methaqualone was introduced to the market in the 1960s as a sedative–hypnotic drug, intended as an alternative to compounds in the barbiturate group [...]
Kaja Tusiewicz, Marcin Zawadzki, Paweł Szpot   +2 more
doaj   +1 more source

State-Dependent Modulation of Slow Wave Motifs towards Awakening

Frontiers in Cellular Neuroscience, 2017
Slow cortical waves that propagate across the cerebral cortex forming large-scale spatiotemporal propagation patterns are a hallmark of non-REM sleep and anesthesia, but also occur during resting wakefulness.
Thomas Knöpfel, Thomas Knöpfel, Thomas Knöpfel, Thomas Knöpfel, Daisuke Shimaoka, Daisuke Shimaoka, Chenchen Song   +6 more
doaj   +1 more source

Beyond the Law: A Qualitative Socio‐Ecological Study of Substance Use Treatment Barriers and Adaptations in Ghana

Journal of Psychiatric and Mental Health Nursing, Volume 33, Issue 5, Page 766-779, October 2026.
ABSTRACT Background Ghana's response to substance use has long been dominated by criminalisation, yet limited research has examined how this policy environment shapes addiction treatment delivery. This study explored the perspectives of mental health nurses providing care to people who use drugs (PWUDs) using a socio‐ecological framework.
Evans F. Kyei, Dorothy Wilson, Grace K. Kyei, Rockson Ansong, Mercy N. Mumba   +4 more
wiley   +1 more source