Results 101 to 110 of about 48,209 (275)
Food Frontiers, Volume 7, Issue 1, January 2026.The protective effects of Medulla Tetrapanacis (MT) water extract on dextran sulfate sodium‐induced ulcerative colitis (UC) were examined both in vivo (mouse and zebrafish) and in vitro. The effect of MT on UC was mediated by regulating macrophage polarization, ameliorating oxidative stress, and preserving an intact intestinal barrier. The effect of MT
Yanfen Cheng +10 more
wiley +1 more source
Characterization of \([^3H]\)Phenobarbital Binding to Rat Brain Membranes [PDF]
, 1984 The binding of \([^3H]\)phenobarbital to rat brain membranes was studied in order to determine its characteristics and specificity. The binding reaction was rapid and occurred at sites of low affinity. \((K_d = 700 μM)\) and very high density \((B_{max} =
Klotz, K.-N. +3 more
core
Heroin Adulterated with the Novel Synthetic Cannabinoid, 5F-MDMB-PINACA: A Case Series [PDF]
, 2020 Introduction: Heroin can be adulterated with various substances that may or may not have pharmacological effects. Here we report a case series of 8 patients who presented to the emergency department after overdose with intravenous heroin preparation ...
Arnold, Ryan +5 more
core
Studies with Thiohexital, an Anesthetic Barbiturate Metabolized with Unusual Rapidity in Man [PDF]
, 1968 Lester C. Mark +3 more
openalex +1 more source
Drug and Alcohol Review, Volume 45, Issue 1, January 2026.ABSTRACT Issues From extracting insights from large‐scale, multimodal data to prevention and support, there is growing interest in the applications and implications of recent advances in Artificial Intelligence (AI) within the fields of addiction, substance use and mental health, which we refer to as ASUM.
Loïs Vanhée, Simone Scarpa
wiley +1 more source
Takotsubo Cardiomyopathy as an Early Complication of Drug-Induced Suicide Attempt
Case Reports in Medicine, 2013 Takotsubo cardiomyopathy typically presents in menopausal women following episodes of intense physical or mental stress. To our knowledge, the literature contains only two documented cases of Takotsubo cardiomyopathy arising following a suicide attempt ...
Massimo Romanò +3 more
doaj +1 more source
Editorial: Glutethimide--an unsafe alternative to barbiturate hypnotics. [PDF]
, 1976 openalex +1 more source
Advanced Science, Volume 12, Issue 47, December 18, 2025.Refractory status epilepticus (RSE) is a life‐threatening neurological emergency with high rates of death and long‐term disability, but treatments for it are often based on limited evidence. RSE is now understood to involve neuroinflammation, which has led to the exploration of anti‐inflammatory and immunomodulatory agents like Tocilizumab. Traditional
Shanika Samarasekera +12 more
wiley +1 more source
Carbogen Inhalation Therapy for Epileptic Seizures: Mechanisms, Evidence, and Future Directions
CNS Neuroscience &Therapeutics, Volume 31, Issue 12, December 2025.Carbogen, a low‐dose CO2/O2 mixture, modulates brain pH to suppress hyperexcitability through rapid and reversible pH‐dependent mechanisms distinct from conventional antiseizure medications (ASMs). Preclinical and small clinical studies show efficacy in focal and absence seizures, whereas variable responses in other types highlight the need for ...
Li Wang +5 more
wiley +1 more source
Multimodal Machine Learning for Automated ICD Coding
, 2019 This study presents a multimodal machine learning model to predict ICD-10 diagnostic codes. We developed separate machine learning models that can handle data from different modalities, including unstructured text, semi-structured text and structured ...
Band, Charlotte +11 more
core