Results 91 to 100 of about 24,812 (221)
Chromatographic descriptors in QSAR study of barbiturates
, 2019 Barbiturate derivatives were evaluated for their parameters of biological activity by applying linear regression and two multivariate methods (Cluster analysis and Principal component analysis).
Vastag, Gyoengyi +4 more
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Affinities of barbiturates for the GABA-receptor complex and A\(_1\) adenosine receptors: A possible explanation of their excitatory effects [PDF]
, 1987 The effects of barbiturates on the GABA·receptor complex and the A\(_1\) adenosine receptor were studied. At the GABA-receptor complex the barbiturates inhibited the binding of [\(^{35}\)S]t-butylbicyclophosphorothionate [\(^{35}\)S]TBPT) and enhanced ...
Schwabe, U. +3 more
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Takotsubo Cardiomyopathy as an Early Complication of Drug-Induced Suicide Attempt
Case Reports in Medicine, 2013 Takotsubo cardiomyopathy typically presents in menopausal women following episodes of intense physical or mental stress. To our knowledge, the literature contains only two documented cases of Takotsubo cardiomyopathy arising following a suicide attempt ...
Massimo Romanò +3 more
doaj +1 more source
Synthesis and spectroscopic characterization of 5-diaminomethylidene barbiturates
Journal of the Brazilian Chemical Society, 2001 The reaction of amines with dithiocyclohexylidenes is a general reaction for the synthesis of diaminomethylidene barbiturates. When diamines of the type H2N-(CH2)n-NH 2 are used as nucleophiles bicyclic compounds are the major reaction products, with ...
Figueroa-Villar José D. +2 more
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Molecular simulation of the hydration Gibbs energy of barbiturates
, 2010 In the present work, molecular dynamics calculations of the Gibbs energy of hydration of 10 different substituted barbiturates in SPC/E water were performed using thermodynamic integration.
António J. Queimada +9 more
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High dose barbiturates in non-traumatic brain swelling: ICP reduction and effect on outcome.
, 1982 High dose barbiturates were used to treat intracranial hypertension in 15 patients with nontraumatic brain lesions; (3 hypertensive hemorrhage, 4 subarachnoid hemorrhage, 5 infarction, 2 global anoxia-ischemia and 2 encephalitis).
S K Kennedy, J Woodcock, A H Ropper
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TISSUE-LIPID SOLUBILITY AND "ADSORPTION" OF BARBITURATES
, 1959 Since the barbiturates comprise one of the most widely used drug groups in modern therapy, their mode of action is of considerable interest and importance.
Irwin, William Cantlon
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Drugs analysis using latex agglutination tests
Тонкие химические технологии, 2011 The method of latex agglutination was used to develop express diagnostics of the most extended groups of drugs (opiates, cannabinoides and barbiturates).
N. М. Solodukhina +3 more
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SYNTHESIS OF NEW PHASE- 1 METABOLITES OF TWO BARBITURATES [PDF]
Journal of Sciences, Islamic Republic of Iran, 1990 The new 4'- hydroxy and 3'- aldehyde phase- 1 metabolites of butobarbitone and pentobarbitone are fully synthesized for the first time. These metabolites were used to idenfity and quantify the natural metabolites in human urine after single and multiple ...
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