Results 91 to 100 of about 61,704 (277)

Population Pharmacokinetics and Dosing Simulations of Pentobarbital in the Pediatric Population

The Journal of Clinical Pharmacology, Volume 66, Issue 5, May 2026.
Abstract Pentobarbital is a barbiturate with sedative and anticonvulsant properties, occasionally used in pediatric patients for preoperative sedation, deep sedation during mechanical ventilation, and seizure control. Despite its long‐standing clinical use, age‐appropriate dosing remains challenging due to variability across studies and limited ...
Victoria Etges Helfer, Lorena Medina‐Aymerich, William J. Muller, Marisa Meyer, Amira Al‐Uzri, Russell McCulloh, Chi D. Hornik, Stephen J. Balevic, Rachel G. Greenberg, Daniel K. Benjamin Jr., Sarah G. Anderson, Daniel Gonzalez, the Best Pharmaceuticals for Children Act—Pediatric Trials Network Steering Committee   +12 more
wiley   +1 more source

Integration of thin layer chromatography and smartphone-based colorimetric analysis for the detection of barbiturates

Green Analytical Chemistry
Barbiturates, a key class of psychoactive drugs, present challenges in accurate detection due to their misuse and involvement in forensic investigations.
Keneuoe Letumanyane, Elisa Kalugendo
doaj   +1 more source

How are normal sleeping controls selected? A systematic review of cross-sectional insomnia studies, and a standardised method to select healthy controls for sleep research [PDF]

, 2008
There appears to be some inconsistency in how normal sleepers (controls) are selected and screened for participation in research studies for comparison with insomnia patients.
Louise Beattie, Colin A. Espie, Simon D. Kyle, Stephany M. Biello, Luyster, Edinger, Heffner, American Sleep Disorders Association, Buysse, Bastien, Ong, Bower, Ree, Barclay, Jones, Horne, Archer, Goel, Taillard, Phipps-Nelson, Carney, Vandewalle, Yoo, Ferguson, Buysse, Dahlgren, Carney, Buysse, Espie, Espie, Lund, Yiend, Espie, Harvey, Harvey, Kyle, Ellis, Ohayon, Barclay, Monk, Barclay, Monk, Wittmann, Roenneberg, Spiegel, Kyle, Lineberger, Wilson, Doghamji, Douglass, Baumann, Espie, Buysse, Meerlo, Kripke, Vgontzas, Kaplan, Van Dongen, Monk, Drake   +59 more
core   +5 more sources

Improving drug identification in overdose death surveillance by using clinical natural language processing models

Journal of Forensic Sciences, Volume 71, Issue 3, Page 1329-1337, May 2026.
Abstract The rising rate of drug‐related deaths in the United States, largely driven by fentanyl, requires timely and accurate surveillance. However, critical overdose data are often buried in free‐text coroner reports, leading to delays and information loss when coded into ICD (International Classification of Disease)‐10 classifications.
Arthur J. Funnell, Panayiotis Petousis, Fabrice Harel‐Canada, Ruby Romero, Alex A. T. Bui, Adam Koncsol, Hritika Chaturvedi, Chelsea Shover, David Goodman‐Meza   +8 more
wiley   +1 more source

Propofol‐Related Infusion Syndrome in Paediatrics—Cautious Consideration or Considered Caution? Case Report

Journal of Paediatrics and Child Health, EarlyView.
Michael A. Stokes, Mark A. J. Dexter, Stephen Jacobe, Jonathan R. Egan, Cindy G. Berrueta Rodriguez, Ashfaque Quadir   +5 more
wiley   +1 more source

A Scoping Review of Non‐Opioid Therapeutics for Opioid Withdrawal: Translational Relevance to Neonatal Opioid Withdrawal Syndrome (NOWS) Research

Clinical and Translational Science, Volume 19, Issue 5, May 2026.
ABSTRACT In the wake of the ongoing opioid epidemic, the incidence of neonatal opioid withdrawal syndrome (NOWS) has surged. While the short‐term effects of NOWS are well‐characterized, long‐term physiological and molecular consequences remain unclear.
Sara L. Mills‐Huffnagle, Oliver M. Lowden, Rhea E. Sullivan, Taryn E. McFadden, Jennifer E. Nyland   +4 more
wiley   +1 more source

Drug Possession Arrests Reported in Alaska, 1986–2017 [PDF]

, 2018
Underlying data is available in both Excel and PDF format. (Download below.)This fact sheet presents data on drug sale possession arrests reported by Alaska law enforcement agencies for the 32-year period 1986 to 2017. Overall, the drug possession arrest
Ervin, Benjamin
core  

Lack of neurosteroid selectivity at δ vs. γ2-containing GABAA receptors in dentate granule neurons [PDF]

, 2020
GAB
Lu, Xinguo, Mennerick, Steven, Zorumski, Charles F   +2 more
core   +1 more source

Identification of Barbiturates [PDF]

Nature, 1959
IN Great Britain the most common poisons at the present time are the 5 : 5′ disubstituted barbiturates. The longer-acting barbiturates, barbitone and phenobarbitone, can accumulate in the body when administered in relatively low therapeutic dosage, and concentrations of these drugs in the blood of about 5 mgm./100 ml. do not necessarily imply poisoning.
openaire   +2 more sources

Novel optimization of multi‐mechanistic approaches for the acute treatment of a migraine attack: A review

Headache: The Journal of Head and Face Pain, Volume 66, Issue 5, Page 1181-1192, May 2026.
Abstract Objective To highlight key factors required to optimize multi‐mechanistic approaches with oral combination treatments for the acute management of a migraine attack. Background Given the complex multi‐factorial nature of migraine, combining treatments with different mechanisms of action should improve outcomes compared to monotherapies, but ...
Stephen Silberstein, Alan M. Rapoport
wiley   +1 more source