Results 101 to 110 of about 22,960 (244)
Molecular simulation of the hydration Gibbs energy of barbiturates
In the present work, molecular dynamics calculations of the Gibbs energy of hydration of 10 different substituted barbiturates in SPC/E water were performed using thermodynamic integration.
António J. Queimada +9 more
core +1 more source
ABSTRACT Podocarpus neriifolius, a widely distributed medicinal plant in South and Southeast Asia, has traditionally been used to treat rheumatism and joint pain. This study aimed to investigate the phytochemical profile and therapeutic potential of the ethanolic leaf extract of P.
Neamul Hoque +9 more
wiley +1 more source
Designing Tailored Molecular Cavities Using Calix[5]arenes as Building Blocks
This account focuses on the shape and dimensions of cavities formed by precisely designed molecular frameworks. It highlights our efforts to construct synthetically tailored cavities based on calix[5]arenes. This study examines the shapes and dimensions of cavities defined by well‐designed molecular structures.
Takehiro Hirao, Takeharu Haino
wiley +1 more source
Synthesis and spectroscopic characterization of 5-diaminomethylidene barbiturates
The reaction of amines with dithiocyclohexylidenes is a general reaction for the synthesis of diaminomethylidene barbiturates. When diamines of the type H2N-(CH2)n-NH 2 are used as nucleophiles bicyclic compounds are the major reaction products, with ...
Figueroa-Villar José D. +2 more
doaj
During the last decade, a new group of drugs, known as the barbiturates, has come into prominence in veterinary medicine as hypnotics and anesthetics. Today we find that these derivatives of barbituric acid are used quite extensively in human medicine ...
Peterson, I.
core
Affinities of barbiturates for the GABA-receptor complex and A\(_1\) adenosine receptors: A possible explanation of their excitatory effects [PDF]
The effects of barbiturates on the GABA·receptor complex and the A\(_1\) adenosine receptor were studied. At the GABA-receptor complex the barbiturates inhibited the binding of [\(^{35}\)S]t-butylbicyclophosphorothionate [\(^{35}\)S]TBPT) and enhanced ...
Schwabe, U. +3 more
core
ABSTRACT Aim This systematic review aims to systematically (1) synthesize factors of nurses’ adherence to double‐checking, (2) identify and describe strategies used to improve adherence, and (3) assess the reported effectiveness of these strategies. Introduction Medication administration errors are a major cause of adverse events.
Junyu Zhao +4 more
wiley +1 more source
Theoretical modeling of oral absorption of barbiturates
The structural characteristics governing gastric absorption of barbiturates were studied using QSAR methodology. The results showed that the gastric absorption rate constant could be modeled using the theoretical parameters, accessible surface area ...
Ghafourian, Taravat +3 more
core +1 more source
Drugs analysis using latex agglutination tests
The method of latex agglutination was used to develop express diagnostics of the most extended groups of drugs (opiates, cannabinoides and barbiturates).
N. М. Solodukhina +3 more
doaj
SYNTHESIS OF NEW PHASE- 1 METABOLITES OF TWO BARBITURATES [PDF]
The new 4'- hydroxy and 3'- aldehyde phase- 1 metabolites of butobarbitone and pentobarbitone are fully synthesized for the first time. These metabolites were used to idenfity and quantify the natural metabolites in human urine after single and multiple ...
doaj

