Results 101 to 110 of about 22,960 (244)

Molecular simulation of the hydration Gibbs energy of barbiturates

open access: yes, 2010
In the present work, molecular dynamics calculations of the Gibbs energy of hydration of 10 different substituted barbiturates in SPC/E water were performed using thermodynamic integration.
António J. Queimada   +9 more
core   +1 more source

Investigating the Phytochemical Constituents, Anti‐Inflammatory, and Neuropharmacological Activities of Podocarpus neriifolius Leaves Through FT‐IR, GC–MS, Experimental Studies, Molecular Docking, and Molecular Dynamics Simulations

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Podocarpus neriifolius, a widely distributed medicinal plant in South and Southeast Asia, has traditionally been used to treat rheumatism and joint pain. This study aimed to investigate the phytochemical profile and therapeutic potential of the ethanolic leaf extract of P.
Neamul Hoque   +9 more
wiley   +1 more source

Designing Tailored Molecular Cavities Using Calix[5]arenes as Building Blocks

open access: yesThe Chemical Record, Volume 26, Issue 6, June 2026.
This account focuses on the shape and dimensions of cavities formed by precisely designed molecular frameworks. It highlights our efforts to construct synthetically tailored cavities based on calix[5]arenes. This study examines the shapes and dimensions of cavities defined by well‐designed molecular structures.
Takehiro Hirao, Takeharu Haino
wiley   +1 more source

Synthesis and spectroscopic characterization of 5-diaminomethylidene barbiturates

open access: yesJournal of the Brazilian Chemical Society, 2001
The reaction of amines with dithiocyclohexylidenes is a general reaction for the synthesis of diaminomethylidene barbiturates. When diamines of the type H2N-(CH2)n-NH 2 are used as nucleophiles bicyclic compounds are the major reaction products, with ...
Figueroa-Villar José D.   +2 more
doaj  

Barbiturates

open access: yes, 1944
During the last decade, a new group of drugs, known as the barbiturates, has come into prominence in veterinary medicine as hypnotics and anesthetics. Today we find that these derivatives of barbituric acid are used quite extensively in human medicine ...
Peterson, I.
core  

Affinities of barbiturates for the GABA-receptor complex and A\(_1\) adenosine receptors: A possible explanation of their excitatory effects [PDF]

open access: yes, 1987
The effects of barbiturates on the GABA·receptor complex and the A\(_1\) adenosine receptor were studied. At the GABA-receptor complex the barbiturates inhibited the binding of [\(^{35}\)S]t-butylbicyclophosphorothionate [\(^{35}\)S]TBPT) and enhanced ...
Schwabe, U.   +3 more
core  

Nurses’ Adherence to Double‐Checking: A Systematic Review of Influencing Factors, Improvement Strategies, and Their Effectiveness

open access: yesInternational Nursing Review, Volume 73, Issue 2, June 2026.
ABSTRACT Aim This systematic review aims to systematically (1) synthesize factors of nurses’ adherence to double‐checking, (2) identify and describe strategies used to improve adherence, and (3) assess the reported effectiveness of these strategies. Introduction Medication administration errors are a major cause of adverse events.
Junyu Zhao   +4 more
wiley   +1 more source

Theoretical modeling of oral absorption of barbiturates

open access: yes, 2002
The structural characteristics governing gastric absorption of barbiturates were studied using QSAR methodology. The results showed that the gastric absorption rate constant could be modeled using the theoretical parameters, accessible surface area ...
Ghafourian, Taravat   +3 more
core   +1 more source

Drugs analysis using latex agglutination tests

open access: yesТонкие химические технологии, 2011
The method of latex agglutination was used to develop express diagnostics of the most extended groups of drugs (opiates, cannabinoides and barbiturates).
N. М. Solodukhina   +3 more
doaj  

SYNTHESIS OF NEW PHASE- 1 METABOLITES OF TWO BARBITURATES [PDF]

open access: yesJournal of Sciences, Islamic Republic of Iran, 1990
The new 4'- hydroxy and 3'- aldehyde phase- 1 metabolites of butobarbitone and pentobarbitone are fully synthesized for the first time. These metabolites were used to idenfity and quantify the natural metabolites in human urine after single and multiple ...
doaj  

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