Results 51 to 60 of about 12,500 (179)
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Rare but severe adverse events (AEs) associated with mRNA‐lipid nanoparticle (LNP) COVID‐19 vaccines, such as Comirnaty, include anaphylaxis and inflammatory organ disorders, but their underlying mechanisms are poorly understood. We aimed to develop an animal model to study these phenomena.
László Dézsi +13 more
wiley +1 more source
Impact of Thalamocortical Input on Barrel Cortex Development
Neuroscience, 2018 The development of cortical maps requires the balanced interaction between genetically determined programs and input/activity-dependent signals generated spontaneously or triggered from the environment. The somatosensory pathway of mice provides an excellent scenario to study cortical map development because of its highly organized cytoarchitecture ...
Martini, Francisco J. +4 more
openaire +4 more sources
Frontiers in Cellular Neuroscience, 2018 During development, activity in the somatosensory cortex is characterized by intermittent oscillatory bursts at gamma (early gamma-oscillations, EGOs) and alpha–beta (spindle-bursts, SBs) frequencies.
Dmitrii Suchkov +3 more
doaj +1 more source
The FEBS Journal, EarlyView.We investigated the potential of iloperidone as an activator of Sigma‐1 receptor (S1R) neuroprotective function in juvenile Huntington's disease (jHD). We tested iloperidone on cortical neurons differentiated from patient‐derived iPSCs, demonstrating that it acts as a S1R agonist, decreasing apoptosis, huntingtin aggregation, and oxidative stress ...
Ersilia Fornetti +11 more
wiley +1 more source
Transcriptomic profiling of subpopulations of mouse embryonic subplate neurons
Journal of Anatomy, EarlyView.To study gene expression in subpopulations of cortical subplate neurons (Lpar1‐EGFP‐positive and D1B‐positive SpN clusters), we applied gene expression profiling, including bulk microarray analysis, single‐cell RNA sequencing (scRNA‐seq), and Visium spatial transcriptomics, and identified both overlapping and unique gene expression signatures ...
Hitomi Achiwa +8 more
wiley +1 more source
Frontiers in Neuroanatomy, 2014 Research based on functional imaging and neuronal recordings in the barrel cortex subdivision of primary somatosensory cortex (SI) of the adult rat has revealed novel aspects of structure-function relationships in this cortex.
Jimmy eStehberg +4 more
doaj +1 more source
New Phytologist, EarlyView.Kimmerera cyanifera gen. et sp. nov. with associated cyanobacteria, holotype UWBM 116051. Summary Through symbiotic associations with microbes, mosses play many important ecological roles in terrestrial ecosystems, such as facilitating trophic interactions and nitrogen cycling.
Zane Walker +4 more
wiley +1 more source
eLife, 2016 Cortical blood flow can be modulated by local activity across a range of species; from barrel-specific blood flow in the rodent somatosensory cortex to the human cortex, where BOLD-fMRI reveals numerous functional borders.
Raya Eilam +3 more
doaj +1 more source
Plant, Cell &Environment, EarlyView.ABSTRACT Na+ can substitute K+ under K+ deficiency conditions, which is denominated as beneficial Na+. Despite its relevance at the physiological level and its interest in agriculture, the mechanisms allowing its uptake and use by plants remain unclear.
Jesús Amo +8 more
wiley +1 more source
Basic and Clinical Neuroscience, 2016 Introduction: Dimethyl sulfoxide (DMSO) is a chemical often used as a solvent for waterinsoluble drugs. In this study, we evaluated the effect of intracerebroventricular (ICV) administration of DMSO on neural response characteristics (in 1200 ...
Narjes Soltani +5 more
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