Results 61 to 70 of about 12,500 (179)
TMEM16A channel signalling microdomains in the regulation of vascular function
The Journal of Physiology, EarlyView.Abstract figure legend Schematic representation of TMEM16A channel signalling microdomains. Calcium influx or calcium release from the endoplasmic/sarcoplasmic reticulum (ER/SR) activates TMEM16A channels through interactions with regulatory proteins in vascular smooth muscle cells or endothelial cells. TMEM16A channel activation drives chloride efflux,
Fênix Araujo, Swapnil K. Sonkusare
wiley +1 more source
PLoS ONE, 2014 Studies utilizing general learning and memory tasks have suggested the importance of neocortical structural plasticity for memory consolidation. However, these learning tasks typically result in learning of multiple different tasks over several days of ...
Lily S Chau +4 more
doaj +1 more source
Müller Glia–Vasculature Interactions in the Developing Retina
Glia, Volume 74, Issue 10, October 2026.Retinal vascular layers form normally despite loss of cholinergic retinal waves. Müller glial processes contact endothelial tip cells early and form Aquaporin‐4‐enriched endfeet. Glial endfoot calcium signals are compartmentalized and occur largely independently of neural activity. ABSTRACT Coordinated signaling among neurons, glia, and the vasculature
Samira Monshietehadi +6 more
wiley +1 more source
Acta Ophthalmologica, Volume 104, Issue 6, Page 705-708, September 2026.Abstract Purpose Fania (Fanny) Kaplan (1890–1918), who was reportedly visually impaired, confessed to the attempted assassination of Soviet leader Vladimir Lenin (1870–1924) in 1918 by shooting him with a pistol. The precise nature of her visual loss is unknown and raises doubts about whether she had sufficient visual function to perform the act ...
Stephen G. Schwartz +3 more
wiley +1 more source
Real-Time Million-Synapse Simulation of Rat Barrel Cortex
Frontiers in Neuroscience, 2014 Simulations of neural circuits are bounded in scale and speed by available computing resources, and particularly by the differences in parallelism and communication patterns between the brain and high-performance computers.
Thomas eSharp +3 more
doaj +1 more source
British Journal of Pharmacology, Volume 183, Issue 18, Page 5586-5601, September 2026.Background and Purpose Sickle cell disease (SCD) is a hereditary blood disorder caused by mutation of β‐globin. In SCD, haemoglobin polymerization causes red blood cells to assume a rigid sickle‐shape leading to neurovascular alterations, including development of vascular dementia – characterized by cognitive impairment and reduced cerebral perfusion ...
Julia Zaccarelli‐Magalhães +11 more
wiley +1 more source
Protein kinase C in the barrel cortex
Acta Neurobiologiae Experimentalis, 2000 Rapid ...
openaire +2 more sources
Journal of Comparative Neurology, Volume 534, Issue 8, August 2026.Two lateral mouse brain sagittal sections labeled, respectively, for Lypd1 (A) and Kcnab3 (B). (A) Lypd1 labels positively cortical Layers 2 and 5 (less heavily), but only at limbic mesocortical sites, forming the limbic ring that separates the unlabeled isocortex (IsoCx) from the unlabeled hippocampal and olfactory allocortex (Hi, Sub, ERh; OlfCx ...
Luis Puelles, Elena Garcia‐Calero
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Early Developmental Neuronal Activity Impacts Oligodendrocyte Differentiation Through AMPA Receptors
Glia, Volume 74, Issue 8, August 2026.In early brain development, neuronal activity reduces OPC differentiation. Decreased neuronal activity changes oligodendrocyte gene expression, including upregulating glutamate receptor genes. AMPA signaling regulates the final stages of OPC differentiation.
Tessa E. Allen +4 more
wiley +1 more source
PLoS ONE, 2014 The rodent whisker-barrel system has been an ideal model for studying somatosensory representations in the cortex. However, it remains a challenge to experimentally stimulate whiskers with a given pattern under spatiotemporal precision.
Tatsuya Honjoh +9 more
doaj +1 more source