Results 41 to 50 of about 106 (103)
Molecular Microbiology, EarlyView.The mitochondrial membrane‐shaping machinery MICOS is assembled surprisingly early during the life cycle of Trypanosoma brucei, before the mitochondrion acquires its mature architecture or full respiratory capacity. Our study also identifies two previously uncharacterized proteins associated with MICOS, providing new insight into the early organization
Michala Boudová +5 more
wiley +1 more source
Predicting membrane protein localization by deep learning on structure and chemistry
Protein Science, Volume 35, Issue 9, September 2026.Abstract It has been known since at least the 1980's that the structure and chemistry of membranes and membrane proteins are matched. Exploiting this fact, a graph neural network model of proteins was trained on experimentally determined membrane protein structures to predict the native membrane environment of transmembrane domains from their structure.
Bivek Pokhrel +3 more
wiley +1 more source
ChemMedChem, Volume 21, Issue 15, 14 August 2026.Temporins, among antimicrobial peptides, are short frog‐derived molecules with potent antibacterial activity. This review highlights chemical optimization strategies applied to temporins A–L, showing how sequence tuning modulates structure, stability, and selectivity, enabling improved activity against resistant pathogens.
Ida Boccino +2 more
wiley +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, Volume 16, Issue 8, Page 1537-1549, August 2026.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
From shaping to functionalization of micro-droplets and particles. [PDF]
Nanoscale Adv, 2021 Song R, Cho S, Shin S, Kim H, Lee J.
europepmc +1 more source
Macromolecular Materials and Engineering, Volume 311, Issue 8, August 2026.FDM‐fabricated PA12 thin‐walled tubes with five hexagonal architected designs (D1–D5) of increasing nodal connectivity were investigated to determine the effects of wall architecture, layer height, and print angle orientation on compressive performance, energy absorption, and dimensional accuracy.
Vigneshwaran Karupaiah +4 more
wiley +1 more source
Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 8, Page 1529-1540, August 2026.ABSTRACT BorF is a short‐chain flavin reductase from a desert soil bacterium that uses NADH to reduce FAD to FADH2, which is used by the tryptophan‐6‐halogenase BorH to chlorinate tryptophan in the biosynthetic pathway of borregomycin A. The X‐ray crystal structure of BorF bound to FAD was solved to 2.37 Å by molecular replacement.
Zheng Ma +3 more
wiley +1 more source
Gating and modulation of a hetero-octameric AMPA glutamate receptor. [PDF]
Nature, 2021 Zhang D +4 more
europepmc +1 more source
Crystal structure of endo‐β‐1,6‐galactanase from Streptomyces avermitilis
Acta Crystallographica Section D, Volume 82, Issue 8, Page 962-971, August 2026.The crystal structure of S. avermitilis endo‐β‐1,6‐galactanase belonging to GH30 subfamily 5 reveals the first structural framework for endo‐β‐1,6‐galactanase. The β‐1,6‐galactobiose‐bound complex identifies the catalytic subsites and a distal secondary sugar‐binding site, providing insight into β‐1,6‐galactan recognition.Endo‐β‐1,6‐galactanases ...
Zui Fujimoto +3 more
wiley +1 more source
Beat-by-Beat Cardiomyocyte T-Tubule Deformation Drives Tubular Content Exchange. [PDF]
Circ Res, 2021 Rog-Zielinska EA +10 more
europepmc +1 more source