Results 71 to 80 of about 1,202,492 (293)

INCLUSIVE TOURISM IN GERMANY: CREATING A BARRIER-FREE ENVIRONMENT

Market Infrastructure
The article analyzes the scientific foundations of inclusive tourism development in Germany, where the creation of a barrier-free environment is viewed as a crucial aspect of socially responsible tourism infrastructure. It has been established that inclusive tourism aligns with modern sustainability requirements, particularly the United Nations ...
Dina Turina, Nelli Leonenko
openaire   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Elucidating the NuclearQuantum Dynamics of Intramolecular Double Hydrogen Transfer in Porphycene [PDF]

, 2019
We address the double hydrogen transfer (DHT) dynamics of the porphycene molecule: A complex paradigmatic system where the making and breaking of H-bonds in a highly anharmonic potential energy surface requires a quantum mechanical treatment not only of ...
Kumagai, Takashi, Litman, Yair, Richardson, Jeremy O., Rossi, Mariana   +3 more
core   +3 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Searching for opportunities to adapt green infrastructure for creating a barrier-free environment in living nature sites

Інтродукція Рослин
This project focuses on adapting Ukraine’s nature reserve areas to meet modern societal challenges, ensuring barrier-free access to natural assets for visitors of all abilities.
Rаisa Matiashuk, Liubov Gubar, Olena Kolesnichenko, Yaroslav Krylov, Rostyslav Radionov, Tetiana Kozachuk, Iryna Tkachenko   +6 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Social interaction activities of older adults: a study based on the outdoor space of old apartment complexes in Tianjin, China

Journal of Asian Architecture and Building Engineering
In the academic community, there is a concern about the effect of neighborhood outdoor spatial design on the social interaction of older adults. However, little attention has been paid to exploring the way of enhancing the mobility and social interaction
Fei Chen, Haobo Zhao, Wei Zhao, Fangzhou Zhao   +3 more
doaj   +1 more source

CREATION OF A BARRIER-FREE ENVIRONMENT IN THE TRAINING OF DENTISTS

SWorld-Ger Conference proceedings, 2022
The growing demand for inclusive healthcare necessitates reforms in the training of future medical professionals, including dentists. This paper explores the formation of an inclusive culture and the readiness of dental students to contribute to a ...
openaire   +1 more source

Effect of grain disorientation on early fatigue crack propagation in face-centred-cubic polycristals: A three-dimensional dislocation dynamics investigation [PDF]

, 2013
Three-dimensional dislocation dynamics simulations are used to study micro-crack interaction with the first micro-structural barrier in face-centred cubic bi-crystals loaded in high cycle fatigue conditions. In the examined configuration, we assumed that
depres, christophe, Fivel, Marc, Reddy, Gv Prasad, Robertson, Christian   +3 more
core   +5 more sources

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source