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Structure and function of the blood–brain barrier
Neurobiology of Disease, 2010 Neural signalling within the central nervous system (CNS) requires a highly controlled microenvironment. Cells at three key interfaces form barriers between the blood and the CNS: the blood–brain barrier (BBB), blood–CSF barrier and the arachnoid barrier.
N Joan Abbott +2 more
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Vesicular Trafficking, a Mechanism Controlled by Cascade Activation of Rab Proteins: Focus on Rab27
Biology, 2023 Vesicular trafficking is essential for the cell to internalize useful proteins and soluble substances, for cell signaling or for the degradation of pathogenic elements such as bacteria or viruses.
Camille Menaceur +4 more
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Appearance of claudin-5+ leukocyte subtypes in the blood and CNS during progression of EAE
Journal of Neuroinflammation, 2021 Background Tight junctions (TJs) are membrane specializations characteristic of barrier-forming membranes, which function to seal the aqueous pathway between endothelial cells or epithelial cells and, thereby, obstruct intercellular solute and cellular ...
Dylan Krajewski +4 more
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Cells, 2023 Within the neurovascular unit, brain pericytes (BPs) are of major importance for the induction and maintenance of the properties of the blood-brain barrier (BBB) carried by the brain microvessel endothelial cells (ECs).
Camille Menaceur +9 more
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The effect of long-term cigarette smoking on selected skin barrier proteins and lipids
Scientific Reports, 2023 The negative impact of cigarette smoking on the skin includes accelerated aging, pigmentation disorders, and impaired wound healing, but its effect on the skin barrier is not completely understood.
Kristýna Hergesell +5 more
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Microbiology Spectrum, 2023 The bacterial component of the gastrointestinal tract microbiome is comprised of hundreds of species, the majority of which live in symbiosis with the host.
Jacob K. Flynn +3 more
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Origine et destination du soin medical [PDF]
Ocula, 2019 Defining the user as both professional and beneficiary, I propose a systemic and participative modelling of project management. This means, in the field of medical care, that the patient is both at the beginning and at the end of the process and that he ...
Philippe Barrier
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Microbiology Spectrum, 2021 The vaginal microbiome composition in humans is categorized based upon the degree to which one of four species of Lactobacillus is dominant (Lactobacillus crispatus, community state type I [CST I], Lactobacillus gasseri, CST II, Lactobacillus iners, CST ...
Charlotte A. Langner +5 more
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Les engrenages de l’innovation. Partenariats industriels et concurrence dans la recherche publique
La Nouvelle Revue du Travail, 2023 This article focuses on the rise of university-industry research centers since the 2000s in France, in a context where national science policy has been increasingly driven by the belief that public research should support technological innovation ...
Julien Barrier
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Conceptual barriers to understanding physical barriers [PDF]
Seminars in Cell & Developmental Biology, 2015 The members of the large family of claudin proteins regulate ion and water flux across the tight junction. Many claudins, e.g. claudins 2 and 15, accomplish this by forming size- and charge-selective paracellular channels. Claudins also appear to be essential for genesis of tight junction strands and recruitment of other proteins to these sites.
Amulya, Lingaraju +4 more
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